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1.
Acta sci. vet. (Impr.) ; 50(supl.1): Pub. 794, 2022. ilus
Artigo em Português | VETINDEX | ID: biblio-1401204

Resumo

Background: Eye neoplasms are infrequent in felines and usually affect the eyelids. Squamous cell carcinoma (SCC) is a neoplasm that occurs owing to recurrent lesions caused by solar radiation and affects the margins of the ears, eyelids, nose and lips of animals with light-colored coat. The clinical signs consist of ulcerated, crusty lesions that may form masses. The diagnosis is established by means of histopathological analysis, and the prognosis depends on the area affected and tumor infiltration. This work aimed to describe a case of SCC in the eyelid with invasion of the eye and its adnexa in a cat, highlighting clinical aspects and the importance of the anatomopathological examination. Case: A female mixed breed senile cat that had been rescued from the streets was brought in for examination. Dehydration and a low body condition score were observed at the general clinical examination. A physical inspection revealed the presence of an ulcerated periocular lesion on the eyelid; the right eye exhibited increased size and loss of definition of its internal structures. The presence of malodorous cerumen in the right ear canal, a tilted head, and walking in circles to the right were also noted. A dysplastic epithelium along with neutrophilic inflammation was observed at the cytopathological analysis. The treatment instituted consisted of administration of antibacterial and anti-inflammatory drugs, and cleaning of the ear. On the follow-up appointment, 2 days later, the patient's condition had worsened and in spite of the supportive therapy administered, the animal died. An anatomopathological study of the body identified, in addition to the alterations in the eyelid and the eye mentioned above, a traumatic lesion with perforation of the mandibular bone, and presence of a brownish content with caseous consistency in the right ear canal. After visualization of the microscopic alterations, the diagnosis established was squamous cell carcinoma of the eyelid with metastases in the optical nerve and choroid blood vessels. Discussion: Squamous cell carcinoma is one of the most common epithelial neoplasms in felines, and can occur in any region of the face; however, the eyelids and the eyes are less frequently affected, which confirms that the case reported here is uncommon. SCC has a higher incidence in female cats older than 10 years of age with light-colored coat and highly exposed to ultraviolet radiation. The case reported here exhibited these characteristics, as the patient had been rescued from the streets where exposition to sunlight is intense. The clinical presentation was consistent with that described in other works, with ulcerated crusty lesions on the eyelid and the nose. Vestibular syndrome, as inferred from the tilted head and circular gait (walking in circles to the right), could be explained by internal otitis, which was observed at necropsy. The cytological analysis of the eye lesion demonstrated the presence of a neutrophilic inflammatory process along with a dysplastic or immature squamous epithelium, which prompted for therapy using antimicrobial and anti-inflammatory drugs. The definitive diagnosis was established with basis on the histopathological analysis, which revealed a pattern of neoplastic cells arranged in clusters or strands connected to the epidermal surface, and the presence of "keratin pearls" consistent with SCC affecting not only the eyelid and the eye, but also invading the optical nerve and the choroid blood vessels. The prognosis was unfavorable owing to the advanced stage of the tumor and concomitant diseases. Even though the development of SCC in the eyelid is relatively common, the occurrence of metastasis in the eye adnexa is rare in felines. An anatomopathological study was required to establish the diagnosis of SCC as the patient's clinical history data were scarce.


Assuntos
Animais , Feminino , Gatos , Carcinoma de Células Escamosas/veterinária , Neoplasias Palpebrais/veterinária , Metástase Neoplásica
2.
Braz. J. Vet. Res. Anim. Sci. (Online) ; 59: e191917, fev. 2022. ilus
Artigo em Inglês | VETINDEX | ID: biblio-1400034

Resumo

Intraocular melanocytic neoplasms are common in dogs. However, the choroidal location of these neoplasms and their infiltration into the optic nerve are unusual. This paper reports a case of primary choroidal melanoma in a 12-year-old male Dachshund. On the first examination, the animal presented left eye blepharospasm, protrusion of the nictitating membrane, conjunctival hyperemia, moderate congestion, hyphema, and intraocular hypertension. Opacity hindered the performance of fundoscopy in the affected eye. The ocular ultrasound examination revealed a cupuliform mass in the choroid. Due to suspected intraocular neoplasia, an exenteration was performed. Histopathological examination revealed primary choroidal melanoma with scleral and optic nerve invasion.(AU)


Neoplasias melanocíticas intraoculares são comuns em cães, contudo, a localização destas neoplasias na coroide e a infiltração delas no nervo óptico são pouco frequentes. O presente trabalho relata um caso de melanoma de coroide primário em um cão da raça Dachshund, com 12 anos de idade. O animal ao primeiro exame apresentou blefaropasmo no olho esquerdo, protrusão da terceira pálpebra, hiperemia conjuntival, congestão moderada, hifema e pressão intraocular elevada. Opacidade de meios transparentes impediu a realização de fundoscopia no olho acometido. O exame ultrassonográfico ocular revelou massa cupuliforme na coroide. Em razão da suspeita de neoplasia intraocular foi realizada exenteração. No exame histopatológico foi diagnosticado melanoma primário em coroide com invasão escleral e do nervo óptico.(AU)


Assuntos
Animais , Cães , Neoplasias da Coroide/diagnóstico por imagem , Doenças Raras/veterinária , Melanoma/diagnóstico por imagem , Cães
3.
Ci. Rural ; 51(4)2021. ilus
Artigo em Inglês | VETINDEX | ID: vti-31147

Resumo

This is a case of medulloepithelioma in a 14-year-old mixed breed gelding horse, presenting a large abnormal mass of tissue involving the entire extension of the right eye. Ophthalmic examination showed deformation and swelling of the eye. The animal showed signs of pain on palpation of the organ, but the specific examination of the systems did not reveal any other changes. Due to the extension of the apparently neoplastic mass and the discomfort experienced by the animal, transpalpebral enucleation procedure was decided. The excised tissue was sent for histopathological analysis, wherein a neoplastic proliferation of neuroectodermal cells was noted. The neoplasm was poorly delimited, unencapsulated, infiltrative, sustained by moderate fibrovascular stroma, and formed cords and rosettes with cells arranged in palisades around the luminal structures (Flexner-Wintersteiner rosettes), suggestive of medulloepithelioma. The immunohistochemical profile was also performed, confirming the diagnosis. The neoplastic cells were immunolabeled to vimentin, S100 protein (S100), and specific neuro enolase (NSE), but not for pan cytokeratin (AE1AE3), glial fibrillary acidic protein (GFAP), and cytokeratin 8/18 (CK8/18). Five months postoperatively, the animal was healthy, without any relapse or evidence of metastasis.(AU)


Esse é um caso de meduloepitelioma em um equino sem raça definida, castrado, de 14 anos de idade, que chegou ao atendimento apresentando grande massa de tecido envolvendo toda a extensão do olho direito. No exame oftálmico, foi observada deformação e aumento de volume ocular. O animal manifestou sinais de dor na palpação do órgão, mas o exame específico dos sistemas não revelou demais alterações. Devido à extensão da massa aparentemente neoplásica e o desconforto experimentado pelo equino foi decidida a realização da enucleação transpalpebral. O tecido excisado foi enviado para exame histopatológico, no qual observou-se proliferação neoplásica de células neuroectodérmicas, de forma mal delimitada, não encapsulada, infiltrativa, sustentada por estroma fibrovascular moderado, e formação de cordões e rosetas, com células dispostas em paliçadas ao redor de estruturas luminais (rosetas de Flexner-Wintersteiner), sugestivo de meduloepitelioma. O perfil imunohistoquímico também foi realizado, confirmando o diagnóstico. As células neoplásicas foram imunomarcadas para vimentina, proteína S100 (S100) e neuro enolase específica (NSE), mas não para pan citoqueratina (AE1AE3), proteína glial fibrilar ácida (GFAP) e citoqueratina 8/18 (CK8 / 18). Após cinco meses da realização do procedimento cirúrgico o animal apresentava-se saudável, sem recidiva ou evidência de metástase.(AU)


Assuntos
Animais , Masculino , Adulto , Neoplasias Oculares/veterinária , Neoplasias Oculares/diagnóstico , Neoplasias Oculares/reabilitação
4.
Acta sci. vet. (Impr.) ; 49(suppl.1): Pub.648-Jan 4, 2021. ilus
Artigo em Português | VETINDEX | ID: biblio-1458510

Resumo

Background: Extramedullary plasmacytoma is a neoplasm originating from plasmacytes with benign behavior, althoughit can present malignant characteristics such as local invasion and metastases in some cases. Primary extramedullary plasmacytoma in the third eyelid is rare in humans and animals and has not yet been described in cats. Thus, the goal of thepresent study is to describe the cytological and histopathological findings of an extramedullary plasmacytoma in a cat’sthird eyelid.Case: A 5-year-old female feline patient with a history of ocular alteration for approximately 30 days was referred tothe ophthalmology service. Upon ophthalmic examination of the left eye, an increase in volume with tissue proliferationwas identified in the third eyelid’s conjunctiva. A collection of material for cytopathological examination was performed.Numerous plasmocytes and atypical lymphocytes with anisocytosis and anisokaryosis were observed, with a possible neoplastic injury being suggested and referred to the patient for surgical removal of the third eyelid. In the histopathologicalanalysis, it was possible to observe several plasma cells and vascular neoformation along the entire conjunctive marginbelow the epithelium. The glands, serous and mucous, present in the fragment, revealed areas of intervening plasmacyticinfiltrate and a large area close to the hyaline cartilage containing intense plasmacytic inflammatory infiltrate with rareneutrophils and macrophages. There was also a structural breakdown of glandular components and lymphocyte cells withmitosis figures and discrete cellular pleomorphism.Discussion: Plasmacytoma is a rare neoplasm in both dogs and cats. The anatomical regions most frequently affected arethe digits, lips, and pinna. Concerning the 3rd eyelid tumor involvement, numerous...


Assuntos
Feminino , Animais , Gatos , Doenças Palpebrais/veterinária , Membrana Nictitante/patologia , Neoplasias Oculares/veterinária , Plasmocitoma/veterinária , Doenças do Gato , Mitomicina/uso terapêutico , Prednisolona/uso terapêutico
5.
Acta sci. vet. (Online) ; 49(suppl.1): Pub. 648, 30 maio 2021. ilus
Artigo em Português | VETINDEX | ID: vti-764708

Resumo

Background: Extramedullary plasmacytoma is a neoplasm originating from plasmacytes with benign behavior, althoughit can present malignant characteristics such as local invasion and metastases in some cases. Primary extramedullary plasmacytoma in the third eyelid is rare in humans and animals and has not yet been described in cats. Thus, the goal of thepresent study is to describe the cytological and histopathological findings of an extramedullary plasmacytoma in a catsthird eyelid.Case: A 5-year-old female feline patient with a history of ocular alteration for approximately 30 days was referred tothe ophthalmology service. Upon ophthalmic examination of the left eye, an increase in volume with tissue proliferationwas identified in the third eyelids conjunctiva. A collection of material for cytopathological examination was performed.Numerous plasmocytes and atypical lymphocytes with anisocytosis and anisokaryosis were observed, with a possible neoplastic injury being suggested and referred to the patient for surgical removal of the third eyelid. In the histopathologicalanalysis, it was possible to observe several plasma cells and vascular neoformation along the entire conjunctive marginbelow the epithelium. The glands, serous and mucous, present in the fragment, revealed areas of intervening plasmacyticinfiltrate and a large area close to the hyaline cartilage containing intense plasmacytic inflammatory infiltrate with rareneutrophils and macrophages. There was also a structural breakdown of glandular components and lymphocyte cells withmitosis figures and discrete cellular pleomorphism.Discussion: Plasmacytoma is a rare neoplasm in both dogs and cats. The anatomical regions most frequently affected arethe digits, lips, and pinna. Concerning the 3rd eyelid tumor involvement, numerous...(AU)


Assuntos
Animais , Feminino , Gatos , Plasmocitoma/veterinária , Neoplasias Oculares/veterinária , Membrana Nictitante/patologia , Doenças Palpebrais/veterinária , Doenças do Gato , Prednisolona/uso terapêutico , Mitomicina/uso terapêutico
6.
Pesqui. vet. bras ; 37(10): 1125-1132, out. 2017. tab, ilus
Artigo em Português | LILACS, VETINDEX | ID: biblio-895349

Resumo

Objetivou-se realizar a caracterização clínica e histopatológica de bulbos oculares de cães e gatos, removidos cirurgicamente por indicação clínica, no período entre 2005-2015. Foram realizados 101 procedimentos de remoção do bulbo ocular, 93 enucleações (92%) e 8 exenterações (8%). Os procedimentos foram realizados em 80 cães, (79% dos casos) e em 21 gatos (21% dos casos). Os cães submetidos à intervenção cirúrgica apresentavam perfurações oculares (n=31, 39%), glaucoma (n=19, 24%), protrusão ocular (n=13, 16%), diagnósticos sugestivos de neoplasia (n=10, 12,5%) e outros (n=3, 2,97%). Dentre os gatos os diagnósticos clínicos compreenderam perfuração ocular (n=9, 49%), glaucoma (n=3, 14,2%), microftalmia (n=3, 14,2%), sugestivo de neoplasia (n=2, 9,5%), protrusão ocular (n=2, 9,5%) e outros (n=2, 9,5%). Vinte e sete amostras de bulbos oculares foram submetidas para avaliação histopatológica, sendo 23 provenientes de cães e quatro de gatos. Dentre as amostras de origem canina, sete exibiram achados histopatológicos compatíveis com glaucoma, sete perfurações oculares, seis neoplasias intraoculares, duas panoftalmites e um quadro de Phthisis bulbi. Nos bulbos oculares de gatos foram diagnosticadas duas neoplasias intraoculares, uma microftalmia e uma perfuração ocular. Constatou-se que o glaucoma secundário, as neoplasias e as perfurações oculares estão entre as principais causas de enucleação em cães, e associadas a alterações primárias como a ceratoconjuntivite seca e as uveítes. Estas afecções, diferentemente das neoplasias, podem ter êxito terapêutico mediante diagnóstico e tratamento precoces, prevenindo a cegueira e a remoção do bulbo ocular.(AU)


This study aimed to carry out the clinical and histopathologic characterization of ocular bulbs from dogs and cats, surgical removed as clinical indication between 2005-2015. Hundred-one procedures were performed, 93 enucleations (92%) and 8 exenterantions (8%). The procedures were performed on 80 dogs (79% of cases) and 21 cats (21% of cases). The dogs underwent to surgery had ocular perfuration (n=31, 39%), glaucoma (n=19, 24%), ocular protrusion (n=13, 16%), diagnosis suggestive of neoplasia (n=10, 12, 5%) and other (n=3, 2.97%). Among the clinical diagnosis cats comprise ocular perforation (n=9, 49%), glaucoma (n=3, 14.2%), microphthalmia (n=3, 14.2%), suggestive of neoplasia (n=2, 9.5%), ocular protrusion (n=2, 9.5%) and other (n=2, 9.5%). Twenty-seven samples of ocular bulbs were sent for histopathologic evaluation in Veterinary Pathology Laboratory, being 23 from dogs and four cats. Among the samples of dogs, seven exhibited histopathologic findings compatible with glaucoma, seven ocular perforations, six had intraocular neoplasias, two panoftalmites and condition of Phthisis bulbi. The ocular bulbs of cats received the diagnosis of two intraocular neoplasias, one microphthalmia and ocular perforation. It was found that the secondary glaucoma and ocular perforations are among the leading causes of enucleation in dogs, and associated with primary disorders such as keratoconjunctivitis sicca and uveitis. These disorders, unlike neoplasia, may have therapeutic success through early diagnosis and treatment, preventing blindness and removal of the eyeball.(AU)


Assuntos
Animais , Gatos , Cães , Enucleação Ocular/veterinária , Gatos/cirurgia , Exenteração Orbitária/veterinária , Cães/cirurgia , Uveíte/veterinária , Glaucoma/veterinária , Ceratoconjuntivite Seca/veterinária , Doenças da Córnea/veterinária , Oftalmopatias/veterinária , Neoplasias Oculares/veterinária
7.
Pesqui. vet. bras ; 37(10): 1125-1132, out. 2017. tab, ilus
Artigo em Português | VETINDEX | ID: vti-19299

Resumo

Objetivou-se realizar a caracterização clínica e histopatológica de bulbos oculares de cães e gatos, removidos cirurgicamente por indicação clínica, no período entre 2005-2015. Foram realizados 101 procedimentos de remoção do bulbo ocular, 93 enucleações (92%) e 8 exenterações (8%). Os procedimentos foram realizados em 80 cães, (79% dos casos) e em 21 gatos (21% dos casos). Os cães submetidos à intervenção cirúrgica apresentavam perfurações oculares (n=31, 39%), glaucoma (n=19, 24%), protrusão ocular (n=13, 16%), diagnósticos sugestivos de neoplasia (n=10, 12,5%) e outros (n=3, 2,97%). Dentre os gatos os diagnósticos clínicos compreenderam perfuração ocular (n=9, 49%), glaucoma (n=3, 14,2%), microftalmia (n=3, 14,2%), sugestivo de neoplasia (n=2, 9,5%), protrusão ocular (n=2, 9,5%) e outros (n=2, 9,5%). Vinte e sete amostras de bulbos oculares foram submetidas para avaliação histopatológica, sendo 23 provenientes de cães e quatro de gatos. Dentre as amostras de origem canina, sete exibiram achados histopatológicos compatíveis com glaucoma, sete perfurações oculares, seis neoplasias intraoculares, duas panoftalmites e um quadro de Phthisis bulbi. Nos bulbos oculares de gatos foram diagnosticadas duas neoplasias intraoculares, uma microftalmia e uma perfuração ocular. Constatou-se que o glaucoma secundário, as neoplasias e as perfurações oculares estão entre as principais causas de enucleação em cães, e associadas a alterações primárias como a ceratoconjuntivite seca e as uveítes. Estas afecções, diferentemente das neoplasias, podem ter êxito terapêutico mediante diagnóstico e tratamento precoces, prevenindo a cegueira e a remoção do bulbo ocular.(AU)


This study aimed to carry out the clinical and histopathologic characterization of ocular bulbs from dogs and cats, surgical removed as clinical indication between 2005-2015. Hundred-one procedures were performed, 93 enucleations (92%) and 8 exenterantions (8%). The procedures were performed on 80 dogs (79% of cases) and 21 cats (21% of cases). The dogs underwent to surgery had ocular perfuration (n=31, 39%), glaucoma (n=19, 24%), ocular protrusion (n=13, 16%), diagnosis suggestive of neoplasia (n=10, 12, 5%) and other (n=3, 2.97%). Among the clinical diagnosis cats comprise ocular perforation (n=9, 49%), glaucoma (n=3, 14.2%), microphthalmia (n=3, 14.2%), suggestive of neoplasia (n=2, 9.5%), ocular protrusion (n=2, 9.5%) and other (n=2, 9.5%). Twenty-seven samples of ocular bulbs were sent for histopathologic evaluation in Veterinary Pathology Laboratory, being 23 from dogs and four cats. Among the samples of dogs, seven exhibited histopathologic findings compatible with glaucoma, seven ocular perforations, six had intraocular neoplasias, two panoftalmites and condition of Phthisis bulbi. The ocular bulbs of cats received the diagnosis of two intraocular neoplasias, one microphthalmia and ocular perforation. It was found that the secondary glaucoma and ocular perforations are among the leading causes of enucleation in dogs, and associated with primary disorders such as keratoconjunctivitis sicca and uveitis. These disorders, unlike neoplasia, may have therapeutic success through early diagnosis and treatment, preventing blindness and removal of the eyeball.(AU)


Assuntos
Animais , Gatos , Cães , Enucleação Ocular/veterinária , Gatos/cirurgia , Exenteração Orbitária/veterinária , Cães/cirurgia , Uveíte/veterinária , Glaucoma/veterinária , Ceratoconjuntivite Seca/veterinária , Doenças da Córnea/veterinária , Oftalmopatias/veterinária , Neoplasias Oculares/veterinária
8.
Acta sci. vet. (Impr.) ; 44(supl): 01-05, 2016. ilus
Artigo em Português | VETINDEX | ID: biblio-1457552

Resumo

Background: The third eyelid neoplasms are uncommon in cats. The squamous cell carcinoma are easily found in head and neck of same species, although is unusual in eye region. The more common localization is eyelid and eyeball, being 60 and 15%, respectively. It could be diagnosed by citology, histopathology, imunohistochemistry and molecular biology. The surgery is more effective treatment, because the tumor can be totally removed and it must available surgical margin. The aim of this study was to report a case of squamous cell carcinoma in third eyelid of a cat and show how it was treated with radical surgery.Case: A 11-year-old spayed female domestic short-haired white and black colored cat was presented for evaluation at Maria Dias Teixeira Hospital of Amazonia Federal Rural University (UFRA), of an red ocular mass fast growth in the left eye for 2 months. Physical exam was within normal limits. The animal presented discomfort on the region, when it was manipulated. The mass was ulcerated and blood-tinged ocular discharge, had 3.3 x 2 cm, beginning on third eyelid and overlay all the eyeball. Blood was collated to make exams. Complete blood count and serum chemistry profiles were within normal ranges, but leukocytes were increased and it was treated with Amoxicillin (22 mg/kg). It was performed biopsy to histopathology and immunohistochemistry diagnose, and radiography and [...]


Assuntos
Animais , Gatos , Carcinoma de Células Escamosas/veterinária , Enucleação Ocular/veterinária , Membrana Nictitante/cirurgia , Membrana Nictitante/patologia , Imuno-Histoquímica/veterinária
9.
Acta sci. vet. (Online) ; 44(supl): 01-05, 2016. ilus
Artigo em Português | VETINDEX | ID: vti-483727

Resumo

Background: The third eyelid neoplasms are uncommon in cats. The squamous cell carcinoma are easily found in head and neck of same species, although is unusual in eye region. The more common localization is eyelid and eyeball, being 60 and 15%, respectively. It could be diagnosed by citology, histopathology, imunohistochemistry and molecular biology. The surgery is more effective treatment, because the tumor can be totally removed and it must available surgical margin. The aim of this study was to report a case of squamous cell carcinoma in third eyelid of a cat and show how it was treated with radical surgery.Case: A 11-year-old spayed female domestic short-haired white and black colored cat was presented for evaluation at Maria Dias Teixeira Hospital of Amazonia Federal Rural University (UFRA), of an red ocular mass fast growth in the left eye for 2 months. Physical exam was within normal limits. The animal presented discomfort on the region, when it was manipulated. The mass was ulcerated and blood-tinged ocular discharge, had 3.3 x 2 cm, beginning on third eyelid and overlay all the eyeball. Blood was collated to make exams. Complete blood count and serum chemistry profiles were within normal ranges, but leukocytes were increased and it was treated with Amoxicillin (22 mg/kg). It was performed biopsy to histopathology and immunohistochemistry diagnose, and radiography and [...](AU)


Assuntos
Animais , Gatos , Carcinoma de Células Escamosas/veterinária , Membrana Nictitante/patologia , Membrana Nictitante/cirurgia , Enucleação Ocular/veterinária , Imuno-Histoquímica/veterinária
10.
Acta sci. vet. (Online) ; 43(supl): 1-5, July 27, 2015. ilus
Artigo em Português | VETINDEX | ID: vti-13972

Resumo

Background: The squamous cell carcinoma (SCC) is the second most common cancer in the oral epithelium of dogs and rarely involves the retrobulbar area. The diagnosis is confirmed with cytological and histopathological exam. Faced with the unusual occurrence of retrobulbar tumors in dogs, we report a case of SCC in the left maxilla, with ipsilateral retrobulbar metastasis, and also highlight clinical aspects of the neoplasia, exams, early diagnosis and therapeutic possibilities.Case: A male dog, 17 years old, with a history of visual loss, enlargement of left eye and prostration after 25 days of a dental treatment. The patient had exophthalmia of the left eye with mild lateral deviation, meibomitis, lagophthalmos, moderate conjunctival hyperemia and episcleral congestion, protrusion of the third eyelid, epiphora, moderate purulent discharge, paracentral corneal degeneration, absence of pupillary reflex to light (direct and consensual) and presence of immature cataract. The Schirmer test and intraocular pressure were normal, as well as complete blood count and biochemical profile. Due to the testy temperament of the animal, the intraoral examination was limited to two-thirds of the jaw in the first appointment. Ocular vitreous ultrasound was performed showing moderate amount of membranous and punctate echoes, as well as medium-high reflectivity were present in all meridians...(AU)


O carcinoma de células escamosas (CCE) é considerado a segunda neoplasia oral não odontogênica, maligna, mais frequente em cães [6] e raramente acomete a região retrobulbar nesta espécie [3,11]. Neoplasias retrobulbares têm representatividade de 4% quando comparadas as de outras estruturas oculares [2] e em 74% das vezes, representam metástases [8].Diante da ocorrência incomum de neoplasias na região retrobulbar em cães, objetivou-se relatar o caso de CCE na maxila esquerda, com metástase retrobulbar ipsilateral, não obstante, ressaltar importantes aspectos da neoplasia que auxiliem no rápido diagnóstico e na escolha terapêutica...(AU)


Assuntos
Animais , Cães , Carcinoma de Células Escamosas/veterinária , Neoplasias Maxilares/veterinária , Exoftalmia/veterinária , Hiperemia/veterinária , Metástase Neoplásica , ética , Doenças do Aparelho Lacrimal/veterinária
11.
Acta sci. vet. (Impr.) ; 43(supl): 1-5, Aug. 14, 2015. ilus
Artigo em Português | VETINDEX | ID: biblio-1457386

Resumo

Background: The squamous cell carcinoma (SCC) is the second most common cancer in the oral epithelium of dogs and rarely involves the retrobulbar area. The diagnosis is confirmed with cytological and histopathological exam. Faced with the unusual occurrence of retrobulbar tumors in dogs, we report a case of SCC in the left maxilla, with ipsilateral retrobulbar metastasis, and also highlight clinical aspects of the neoplasia, exams, early diagnosis and therapeutic possibilities.Case: A male dog, 17 years old, with a history of visual loss, enlargement of left eye and prostration after 25 days of a dental treatment. The patient had exophthalmia of the left eye with mild lateral deviation, meibomitis, lagophthalmos, moderate conjunctival hyperemia and episcleral congestion, protrusion of the third eyelid, epiphora, moderate purulent discharge, paracentral corneal degeneration, absence of pupillary reflex to light (direct and consensual) and presence of immature cataract. The Schirmer test and intraocular pressure were normal, as well as complete blood count and biochemical profile. Due to the testy temperament of the animal, the intraoral examination was limited to two-thirds of the jaw in the first appointment. Ocular vitreous ultrasound was performed showing moderate amount of membranous and punctate echoes, as well as medium-high reflectivity were present in all meridians...


O carcinoma de células escamosas (CCE) é considerado a segunda neoplasia oral não odontogênica, maligna, mais frequente em cães [6] e raramente acomete a região retrobulbar nesta espécie [3,11]. Neoplasias retrobulbares têm representatividade de 4% quando comparadas as de outras estruturas oculares [2] e em 74% das vezes, representam metástases [8].Diante da ocorrência incomum de neoplasias na região retrobulbar em cães, objetivou-se relatar o caso de CCE na maxila esquerda, com metástase retrobulbar ipsilateral, não obstante, ressaltar importantes aspectos da neoplasia que auxiliem no rápido diagnóstico e na escolha terapêutica...


Assuntos
Animais , Cães , Carcinoma de Células Escamosas/veterinária , Exoftalmia/veterinária , Hiperemia/veterinária , Metástase Neoplásica , Neoplasias Maxilares/veterinária , Ética , Doenças do Aparelho Lacrimal/veterinária
12.
Acta sci. vet. (Impr.) ; 38(2): 197-200, 2010.
Artigo em Inglês | VETINDEX | ID: biblio-1456772

Resumo

Squamous cell carcinoma (SCC) is a neoplastic disease of the squamous epithelial cells that has been rarely described in the literature. This neoplasm affects the eyelid, conjunctiva and third eyelid, as well as the cornea. Corneal SCC is a neoplastic lesion characterized by a pink, typically irregular mass protruding from the epithelial surface of the cornea. Canine corneal SCC has been associated with chronic keratoconjunctivitis sicca, or keratitis secondary to exophthalmia and is common in humans, horses and cows. The treatment is surgical with excision of the lesion of the ocular surface. This paper reported a study of a dog with corneal SCC, which was successfully treated with a superficial lamellar keratectomy excision combined with cryosurgery.


Assuntos
Animais , Carcinoma/patologia , Cães/classificação , Crioterapia , Córnea/anatomia & histologia
13.
Acta sci. vet. (Online) ; 38(2): 197-200, 2010.
Artigo em Inglês | VETINDEX | ID: vti-5005

Resumo

Squamous cell carcinoma (SCC) is a neoplastic disease of the squamous epithelial cells that has been rarely described in the literature. This neoplasm affects the eyelid, conjunctiva and third eyelid, as well as the cornea. Corneal SCC is a neoplastic lesion characterized by a pink, typically irregular mass protruding from the epithelial surface of the cornea. Canine corneal SCC has been associated with chronic keratoconjunctivitis sicca, or keratitis secondary to exophthalmia and is common in humans, horses and cows. The treatment is surgical with excision of the lesion of the ocular surface. This paper reported a study of a dog with corneal SCC, which was successfully treated with a superficial lamellar keratectomy excision combined with cryosurgery.(AU)


Assuntos
Animais , Cães/classificação , Carcinoma/patologia , Córnea/anatomia & histologia , Crioterapia
14.
Artigo em Inglês, Espanhol, Português | VETINDEX | ID: biblio-1480953

Resumo

Muitos tumores intraoculares são reportados nos animais, porém o meduloepitelioma teratoide maligno é um tumor intraocular originário do epitélio medular primitivo, raro tanto nos animais quanto em seres humanos. Sua presença ocorre geralmente na infância; entretanto, alguns trabalhos têm relatado seu aparecimento em idosos. Seu crescimento é lento, e sua invasão local agressiva, porém seu caráter metastático é baixo. O presente artigo relata um caso de meduloepitelioma teratoide maligno em um cão sem raça definida, macho, de doze anos, com histórico de glaucoma buftálmico, tratado com terapia medicamentosa havia cinco anos, que retornou com a presença de uma massa intraocular. Após a enucleação, o material foi encaminhado para exame histopatológico e posterior imuno-histoquímica para confirmação do diagnóstico. Após um ano o animal encontra-se bem e sem recorrências de metástase.


Although there are several intraocular tumors reported in animals, the malignant teratoid medulloepithelioma is an intraocular tumor which originates from the primitive medullary epithelium and it is rare both in animals and humans. This tumor usually occurs during childhood; nonetheless, some reports have shown its occurrence in the elderly. This tumor development is slow and it is locally aggressive, but its metastatic character is low. This article describes the case of a malignant intraocular medulloepithelioma in a twelve-year-old male stray dog with a history of buphthalmic glaucoma, which had been treated medically five years before, and returned with an intraocular mass. After enucleation, the material was sent to histopatological examination and subsequent immunohistochemistry to confirm the diagnosis. A year after the procedure the animal is healthy and there are no metastases.


Existe una gran cantidad de tumores intraoculares en animales. El meduloepitelioma teratoide maligno representa un tipo de tumor intraocular originado en el epitelio medular primitivo, de rara presentación tanto en animales como en seres humanos. Suele aparecer generalmente en la infancia, aunque hay algunos trabajos relatando su presentación en ancianos. Su crecimiento es lento y es agresivo localmente, aunque posee baja capacidad de metástasis. Este trabajo relata un caso de meduloepitelioma teratoide maligno en un perro mestizo, macho de doce años, con una historia de glaucoma y buftalmia, que había sido tratado con medicamentos cinco años antes. Este paciente retornó para consulta presentando una masa intra ocular. Después de realizarse la enucleación, fueron enviadas muestras para examen histopatológico e inmunohistoquímica, donde se confirmó el diagnóstico del tumor. Un año después el animal se encuentra en buenas condiciones y sin presencia de metástasis.


Assuntos
Animais , Cães , Metástase Neoplásica , Neoplasias/patologia , Olho/anatomia & histologia , Cães/classificação
15.
Clín. Vet. ; 19(108): 80-85, 2014.
Artigo em Inglês, Espanhol, Português | VETINDEX | ID: vti-10362

Resumo

Muitos tumores intraoculares são reportados nos animais, porém o meduloepitelioma teratoide maligno é um tumor intraocular originário do epitélio medular primitivo, raro tanto nos animais quanto em seres humanos. Sua presença ocorre geralmente na infância; entretanto, alguns trabalhos têm relatado seu aparecimento em idosos. Seu crescimento é lento, e sua invasão local agressiva, porém seu caráter metastático é baixo. O presente artigo relata um caso de meduloepitelioma teratoide maligno em um cão sem raça definida, macho, de doze anos, com histórico de glaucoma buftálmico, tratado com terapia medicamentosa havia cinco anos, que retornou com a presença de uma massa intraocular. Após a enucleação, o material foi encaminhado para exame histopatológico e posterior imuno-histoquímica para confirmação do diagnóstico. Após um ano o animal encontra-se bem e sem recorrências de metástase.(AU)


Although there are several intraocular tumors reported in animals, the malignant teratoid medulloepithelioma is an intraocular tumor which originates from the primitive medullary epithelium and it is rare both in animals and humans. This tumor usually occurs during childhood; nonetheless, some reports have shown its occurrence in the elderly. This tumor development is slow and it is locally aggressive, but its metastatic character is low. This article describes the case of a malignant intraocular medulloepithelioma in a twelve-year-old male stray dog with a history of buphthalmic glaucoma, which had been treated medically five years before, and returned with an intraocular mass. After enucleation, the material was sent to histopatological examination and subsequent immunohistochemistry to confirm the diagnosis. A year after the procedure the animal is healthy and there are no metastases.(AU)


Existe una gran cantidad de tumores intraoculares en animales. El meduloepitelioma teratoide maligno representa un tipo de tumor intraocular originado en el epitelio medular primitivo, de rara presentación tanto en animales como en seres humanos. Suele aparecer generalmente en la infancia, aunque hay algunos trabajos relatando su presentación en ancianos. Su crecimiento es lento y es agresivo localmente, aunque posee baja capacidad de metástasis. Este trabajo relata un caso de meduloepitelioma teratoide maligno en un perro mestizo, macho de doce años, con una historia de glaucoma y buftalmia, que había sido tratado con medicamentos cinco años antes. Este paciente retornó para consulta presentando una masa intra ocular. Después de realizarse la enucleación, fueron enviadas muestras para examen histopatológico e inmunohistoquímica, donde se confirmó el diagnóstico del tumor. Un año después el animal se encuentra en buenas condiciones y sin presencia de metástasis.(AU)


Assuntos
Animais , Cães , Neoplasias/patologia , Olho/anatomia & histologia , Metástase Neoplásica , Cães/classificação
16.
Acta sci. vet. (Online) ; 38(2): 197-200, 2010.
Artigo em Português | VETINDEX | ID: vti-733558

Resumo

Background:  :  :  Squamous cell carcinoma (SCC) is a neoplastic disease of the squamous epithelial cells that has been rarely described in the literature. This neoplasm affects the eyelid, conjunctiva and third eyelid, as well as the cornea. Corneal SCC is a neoplastic lesion characterized by a pink, typically irregular mass protruding from the epithelial surface of the cornea. Canine corneal SCC has been associated with chronic keratoconjunctivitis sicca, or keratitis secondary to exophthalmia and is common in humans, horses and cows. The treatment is surgical with excision of the lesion of the ocular surface. This paper reported a study of a dog with corneal SCC, which was successfully treated with a superficial lamellar keratectomy excision combined with cryosurgery. Case: An 8-year-old male English bulldog was presented for the evaluation of a red mass on its left eye that had progressively grown over a 1-year period. The mass was approximately 6mm in diameter and it was elevated from 3 to 4 mm above the corneal surface with no expansion onto bulbar conjunctiva. At physical examination it was normal except for the ocular disease. A complete blood cell count and serum chemical profiles were unremarkable. The radiographic evaluation did not demonstrate any evidence of metastasis. The mass was excised by a superficial lamellar keratectomy and the surgical bed was frozen with

17.
Acta sci. vet. (Online) ; 38(2): 197-200, 2010.
Artigo em Português | VETINDEX | ID: vti-732229

Resumo

Background:  :  :  Squamous cell carcinoma (SCC) is a neoplastic disease of the squamous epithelial cells that has been rarely described in the literature. This neoplasm affects the eyelid, conjunctiva and third eyelid, as well as the cornea. Corneal SCC is a neoplastic lesion characterized by a pink, typically irregular mass protruding from the epithelial surface of the cornea. Canine corneal SCC has been associated with chronic keratoconjunctivitis sicca, or keratitis secondary to exophthalmia and is common in humans, horses and cows. The treatment is surgical with excision of the lesion of the ocular surface. This paper reported a study of a dog with corneal SCC, which was successfully treated with a superficial lamellar keratectomy excision combined with cryosurgery. Case: An 8-year-old male English bulldog was presented for the evaluation of a red mass on its left eye that had progressively grown over a 1-year period. The mass was approximately 6mm in diameter and it was elevated from 3 to 4 mm above the corneal surface with no expansion onto bulbar conjunctiva. At physical examination it was normal except for the ocular disease. A complete blood cell count and serum chemical profiles were unremarkable. The radiographic evaluation did not demonstrate any evidence of metastasis. The mass was excised by a superficial lamellar keratectomy and the surgical bed was frozen with

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