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1.
Acta sci. vet. (Impr.) ; 47(suppl.1): Pub.383-2019. ilus
Artigo em Inglês | VETINDEX | ID: biblio-1458147

Resumo

Background: Deep fungal infections of the orbit and nasal passages causing rhinitis and ulcerative keratomycosis areuncommonly reported in cats. Hyalohyphomycetes and phaeohyphomycetes have rarely been associated with this disorder.Sino-orbital fungal diseases are emerging and more invasive than sino-nasal fungal diseases with poor response to therapyand a worse prognosis. Brachycephalic feline breeds seem to be at increased risk for development of upper respiratoryfungal diseases. Diagnosis is based on the demonstration of fungal hyphae by cytology or histology and definitive confirmation by fungal culture and molecular methods. This is the first case report of a cat with clinical mixed fungal ball withAspergillus and Scopulariopsis in Brazil.Case: A 3-year-old male Persian cat, in São José city, Santa Catarina, Brazil, was presented with exophthalmos and corneal ulcer of the left eye and protrusion, hyperemia, quemosis and fibroses of the left third eyelid. The retropulsion of theglobe was negative in this eyeball and a presumptive diagnosis of a retrobulbar mass was made. The patient underwenta surgical procedure for inspection and collection of samples for bacterial and mycological culture. Culture revealed nobacterial growth, however, unique and abundant growth of Aspergillus spp. was present. A subconjunctival enucleation ofthe left eye was made and the mass was sent for histopathology examination. Histology showed inflammatory proliferativenecrotizing pyogranulomatous reaction; with the presence of severe fungal infection evidenced by large number of hyalineseptated regular and irregular mold hyphae. Molecular identification was performed using panfungal primers (ITS3-F /ITS4-R). Patient was treated with systemic itraconazole associated with amphotericin B and topical clotrimazole. A massstarted to grow rapidly in the left pterygopalatine fossa and was surgically removed, but recurrence occurred seven daysafter...


Assuntos
Animais , Gatos , Aspergillus , Bulbo Olfatório/patologia , Micoses/veterinária , Scopulariopsis , Órbita/patologia , Doenças Respiratórias/veterinária
2.
Acta sci. vet. (Online) ; 47(suppl.1): Pub. 383, Apr. 10, 2019. ilus
Artigo em Inglês | VETINDEX | ID: vti-19114

Resumo

Background: Deep fungal infections of the orbit and nasal passages causing rhinitis and ulcerative keratomycosis areuncommonly reported in cats. Hyalohyphomycetes and phaeohyphomycetes have rarely been associated with this disorder.Sino-orbital fungal diseases are emerging and more invasive than sino-nasal fungal diseases with poor response to therapyand a worse prognosis. Brachycephalic feline breeds seem to be at increased risk for development of upper respiratoryfungal diseases. Diagnosis is based on the demonstration of fungal hyphae by cytology or histology and definitive confirmation by fungal culture and molecular methods. This is the first case report of a cat with clinical mixed fungal ball withAspergillus and Scopulariopsis in Brazil.Case: A 3-year-old male Persian cat, in São José city, Santa Catarina, Brazil, was presented with exophthalmos and corneal ulcer of the left eye and protrusion, hyperemia, quemosis and fibroses of the left third eyelid. The retropulsion of theglobe was negative in this eyeball and a presumptive diagnosis of a retrobulbar mass was made. The patient underwenta surgical procedure for inspection and collection of samples for bacterial and mycological culture. Culture revealed nobacterial growth, however, unique and abundant growth of Aspergillus spp. was present. A subconjunctival enucleation ofthe left eye was made and the mass was sent for histopathology examination. Histology showed inflammatory proliferativenecrotizing pyogranulomatous reaction; with the presence of severe fungal infection evidenced by large number of hyalineseptated regular and irregular mold hyphae. Molecular identification was performed using panfungal primers (ITS3-F /ITS4-R). Patient was treated with systemic itraconazole associated with amphotericin B and topical clotrimazole. A massstarted to grow rapidly in the left pterygopalatine fossa and was surgically removed, but recurrence occurred seven daysafter...(AU)


Assuntos
Animais , Gatos , Aspergillus , Scopulariopsis , Micoses/veterinária , Órbita/patologia , Bulbo Olfatório/patologia , Doenças Respiratórias/veterinária
3.
Acta sci. vet. (Online) ; 43(supl): 1-5, July 27, 2015. ilus
Artigo em Português | VETINDEX | ID: vti-13972

Resumo

Background: The squamous cell carcinoma (SCC) is the second most common cancer in the oral epithelium of dogs and rarely involves the retrobulbar area. The diagnosis is confirmed with cytological and histopathological exam. Faced with the unusual occurrence of retrobulbar tumors in dogs, we report a case of SCC in the left maxilla, with ipsilateral retrobulbar metastasis, and also highlight clinical aspects of the neoplasia, exams, early diagnosis and therapeutic possibilities.Case: A male dog, 17 years old, with a history of visual loss, enlargement of left eye and prostration after 25 days of a dental treatment. The patient had exophthalmia of the left eye with mild lateral deviation, meibomitis, lagophthalmos, moderate conjunctival hyperemia and episcleral congestion, protrusion of the third eyelid, epiphora, moderate purulent discharge, paracentral corneal degeneration, absence of pupillary reflex to light (direct and consensual) and presence of immature cataract. The Schirmer test and intraocular pressure were normal, as well as complete blood count and biochemical profile. Due to the testy temperament of the animal, the intraoral examination was limited to two-thirds of the jaw in the first appointment. Ocular vitreous ultrasound was performed showing moderate amount of membranous and punctate echoes, as well as medium-high reflectivity were present in all meridians...(AU)


O carcinoma de células escamosas (CCE) é considerado a segunda neoplasia oral não odontogênica, maligna, mais frequente em cães [6] e raramente acomete a região retrobulbar nesta espécie [3,11]. Neoplasias retrobulbares têm representatividade de 4% quando comparadas as de outras estruturas oculares [2] e em 74% das vezes, representam metástases [8].Diante da ocorrência incomum de neoplasias na região retrobulbar em cães, objetivou-se relatar o caso de CCE na maxila esquerda, com metástase retrobulbar ipsilateral, não obstante, ressaltar importantes aspectos da neoplasia que auxiliem no rápido diagnóstico e na escolha terapêutica...(AU)


Assuntos
Animais , Cães , Carcinoma de Células Escamosas/veterinária , Neoplasias Maxilares/veterinária , Exoftalmia/veterinária , Hiperemia/veterinária , Metástase Neoplásica , ética , Doenças do Aparelho Lacrimal/veterinária
4.
Acta sci. vet. (Impr.) ; 43(supl): 1-5, Aug. 14, 2015. ilus
Artigo em Português | VETINDEX | ID: biblio-1457386

Resumo

Background: The squamous cell carcinoma (SCC) is the second most common cancer in the oral epithelium of dogs and rarely involves the retrobulbar area. The diagnosis is confirmed with cytological and histopathological exam. Faced with the unusual occurrence of retrobulbar tumors in dogs, we report a case of SCC in the left maxilla, with ipsilateral retrobulbar metastasis, and also highlight clinical aspects of the neoplasia, exams, early diagnosis and therapeutic possibilities.Case: A male dog, 17 years old, with a history of visual loss, enlargement of left eye and prostration after 25 days of a dental treatment. The patient had exophthalmia of the left eye with mild lateral deviation, meibomitis, lagophthalmos, moderate conjunctival hyperemia and episcleral congestion, protrusion of the third eyelid, epiphora, moderate purulent discharge, paracentral corneal degeneration, absence of pupillary reflex to light (direct and consensual) and presence of immature cataract. The Schirmer test and intraocular pressure were normal, as well as complete blood count and biochemical profile. Due to the testy temperament of the animal, the intraoral examination was limited to two-thirds of the jaw in the first appointment. Ocular vitreous ultrasound was performed showing moderate amount of membranous and punctate echoes, as well as medium-high reflectivity were present in all meridians...


O carcinoma de células escamosas (CCE) é considerado a segunda neoplasia oral não odontogênica, maligna, mais frequente em cães [6] e raramente acomete a região retrobulbar nesta espécie [3,11]. Neoplasias retrobulbares têm representatividade de 4% quando comparadas as de outras estruturas oculares [2] e em 74% das vezes, representam metástases [8].Diante da ocorrência incomum de neoplasias na região retrobulbar em cães, objetivou-se relatar o caso de CCE na maxila esquerda, com metástase retrobulbar ipsilateral, não obstante, ressaltar importantes aspectos da neoplasia que auxiliem no rápido diagnóstico e na escolha terapêutica...


Assuntos
Animais , Cães , Carcinoma de Células Escamosas/veterinária , Exoftalmia/veterinária , Hiperemia/veterinária , Metástase Neoplásica , Neoplasias Maxilares/veterinária , Ética , Doenças do Aparelho Lacrimal/veterinária
5.
Ci. Rural ; 44(8): 1431-1436, Aug. 2014. ilus
Artigo em Inglês | VETINDEX | ID: vti-27027

Resumo

The effects of sildenafil on retrobulbar and retinal circulation were studied in 18 adult male, albino, homozygous rabbits, of the New Zealand White breed, randomly divided into 3 groups of 6 animals, for drug treatment at a dose of 3.5mg kg-1 every 24 hours, for 7, 15 and 30 days. Nine animals used for control were treated with saline solution at 0.9%. It was evaluated intraocular pressure (IOP), mean arterial pressure (MAP), ocular perfusion pressure (PPO), B-mode ultrasonography and fluorescein angiography before and at the end of treatments. A slight decrease in results of IOP, MAP and PPO after treatment with sildenafil was evident, however, there was no statistical significance. It was observed significant increased diameter of the ophthalmic artery after 7 and 30 days of treatment and decreased mean arterial pressure after 7, 15 and 30 days of treatment, with no statistical difference. On fluorescein angiography, it was observed that the arterial, arteriovenous and venous stages initiated more rapidly in animals after treatment, with significant difference on the arteriovenous stage at the 7th and 15th days. It was possible to admit that the sildenafil citrate improves blood circulation in the retina of rabbits, by increasing the speed of blood flow and decreasing the perfusion pressure.(AU)


Os efeitos do sildenafil sobre a circulação retrobulbar e a retiniana foram estudados em 18 coelhos machos adultos, albinos, homozigotos, da raça Nova Zelândia Branco, distribuídos aleatoriamente em 3 grupos de 6 animais, para tratamento com o fármaco na dose de 3,5mg kg-1 a cada 24 horas, por 7, 15 e 30 dias. Nove animais foram utilizados para controle, tratados com solução fisiológica a 0.9%. Foram avaliadas a pressão intraocular (PIO), a pressão arterial média (PAM) e a pressão de perfusão ocular (PPO), ultrassonografia em modo-B e a angiografia fluoresceínica, antes e ao término dos tratamentos. Evidenciou-se discreta diminuição nos resultados da PIO, da PAM e da PPO após tratamento com sildenafil, entretanto não houve significância estatística. Observou-se aumento significativo do diâmetro da artéria oftálmica após 7 e 30 dias de tratamento e diminuição da pressão arterial média após 7, 15 e 30 dias de tratamento, sem diferença estatística. À angiografia fluoresceínica, observou-se que as fases arterial, artério-venosa e venosa iniciaram-se mais rapidamente nos animais após o tratamento, com diferença significativa na fase artério-venosa ao 7o e 15o dias. Foi possível admitir que o citrato de sildenafil melhora a circulação de sangue na retina de coelhos, através do aumento da velocidade do fluxo de sangue e diminuição da pressão de perfusão.(AU)


Assuntos
Animais , Masculino , Coelhos , Citrato de Sildenafila/administração & dosagem , Citrato de Sildenafila/uso terapêutico , Retina/efeitos dos fármacos , Circulação Sanguínea/efeitos dos fármacos
6.
Tese em Português | VETTESES | ID: vtt-213462

Resumo

Os bloqueios anestésicos concomitantes à anestesia inalatória são protocolos seguros para o controle da dor na Medicina Veterinária. A utilização da ultrassonografia para guiar a agulha nos bloqueios anestésicos retrobulbares é necessária a fim de atingir o local correto da deposição do anestésico local e evitar possíveis traumas ao bulbo ocular. Neste trabalho, foi realizada a abordagem da agulha dentro do plano ultrassonográfico com deposição de dois volumes de solução corante. Foi realizado um estudo anatômico em cadáveres caninos para compreensão das estruturas anatômicas envolvidas. Foi aplicado corante com dois volumes distintos (0,05 e 0,1 mL/cm de distância entre o osso occipital e incisura frontomaxilar) no espaço intraconal. Os resultados observados após ressecção das estruturas oculares com o corante mostraram-se semelhantes nos dois volumes, com diferença apenas na forma da dispersão no interior no cone óptico. Como a dispersão do corante no espaço intraconal foi semelhante nos dois volumes, pode-se esperar acinesia e analgesia do bulbo óptico em situações clínicas com menores volumes. Contudo, a redução dos volumes utilizados em bloqueios anestésicos só é possível quando há o correto posicionamento da agulha e, nesse caso, a ultrassonografia permite a visualização em tempo real da dispersão do anestésico no interior do cone óptico.


Anesthetic blocks concomitant with inhalational anesthesia are currently safe protocols for pain control in veterinary medicine. The use of ultrasonography to guide the needle into retrobulbar blocks is necessary to achieve the correct site to deposition of local anesthetic and to avoid possible trauma to the ocular bulb. In this study, the needle approach was performed within the plane of the ultrasonographic plane with deposition of two volumes of dye solution. Initially an anatomical study of canine corpses was performed to understand the anatomical structures involved. Subsequently, the dye was applied with two distinct volumes (0.1 and 0.05 mL / cm of distance between the occipital bone and the frontomaxillary fissure) in the intraconal space. The results observed after resection of the ocular structures with the dye were similar in both volumes, with difference only in the way of the dispersion inside the optical cone. We concluded that, as the dye dispersion in the intraconal space was similar in both volumes, akinesia and analgesia of the optic bulb could be expected in clinical situations with lower volumes. However, reduction of volumes used in anesthetic blocks is only possible when the needle is correctly positioned and, in this case, the ultrasound allows real-time visualization of the dispersion of the anesthetic in the optical cone

7.
Arq. bras. med. vet. zootec ; 65(4): 1017-1023, Aug. 2013. ilus
Artigo em Inglês | VETINDEX | ID: vti-9790

Resumo

A 12-year-old male English Pointer was examined due to a soft-tissue swelling at the medial canthus of the right orbital region, which was causing facial deformity. The dog had epiphora, purulent nasal discharge, epistaxis, dyspnea, and progressive weight loss. An intraoral mass was observed near the right maxillary premolars. Neoplastic disease was diagnosed based on ancillary tests, which included blood work, skull and intraoral radiographs, ocular ultrasonography and computed tomography. Histopathology revealed transitional carcinoma involving the nasal and oral cavities, maxilla, bony orbit and retrobulbar space. Nasal tumors represent approximately 2% of all tumors diagnosed in this species. Transitional carcinoma is the second most common type of malignant epithelial tumor in the nasal sinuses. This case illustrates the extensive destruction of the soft and bony tissues of the face, including the bony orbit that this type of tumor can cause.(AU)


Um cão da raça Pointer Inglês, de 12 anos de idade, foi encaminhado para avaliação clínica por apresentar aumento de volume no canto temporal (medial) da órbita direita, o qual estava causando deformidade facial. O cão apresentava epífora, secreção nasal mucopurulenta, epistaxe, dispnésia e perda de peso progressiva. Uma massa foi observada na cavidade oral, próxima aos dentes pré-molares, do lado direito da face. Suspeitou-se de proliferação neoplásica baseando-se nos testes auxiliares, entre os quais: radiografia craniana e oral, ultrassonografia ocular e tomografia computadorizada. A análise histopatológica da massa revelou tratar-se de carcinoma transicional envolvendo as cavidades oral e nasal, os ossos da maxila e da órbita, além do espaço retrobulbar. Os tumores da cavidade nasal representam aproximadamente 2% de todos os tumores diagnosticados nessa espécie. O carcinoma transicional é o segundo tipo de neoplasia epitelial maligna mais comum nos seios nasais de cães. Este trabalho descreve a destruição extensiva dos tecidos moles e dos ossos da face e chama atenção para o fato de que esse tipo de neoplasia deve ser considerado nas doenças da órbita.(AU)


Assuntos
Animais , Carcinoma/patologia , Neoplasias , Doenças Respiratórias/patologia , Osso e Ossos/anatomia & histologia , Cães , Tomografia
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