Survival and disease-free interval of cats with mammary carcinoma treated with chain mastectomy

Background: Mammary tumors are extremely common in cats and have high metastatic rates with poor prognosis. The main objective of the present study was to evaluate the disease free interval and survival in cats undergoing radical mastectomy as sole therapy. Materials, Methods & Results: Twenty cats with mammary tumors and no evidence of distant metastasis were studied. General health and concomitant diseases were assessed by clinical and hematological examination. Thoracic radiographs and abdominal ultrasonography were performed to evaluate thoracic and abdominal metastases. All cats underwent chain mastectomy, which was unilateral when tumor was present in one mammary chain, and bilateral in steps if tumors were present in both mammary chains. Intact cats were spayed. An elliptical incision was made around the mammary chain with a three centimeter margin around tumor. Regional lymph node was removed. Mean age was ten years, and 14 cats were mixed breed, three were Persian and two were Siamese. Fifteen cats were spayed at tumor diagnosis, but only three had been spayed before one year old. The inguinal mammary glands were the most affected, followed by abdominal and thoracic glands. Histopathology diagnosed well-differentiated adenocarcinoma in eight cases, moderately differentiated adenocarcinoma in nine cases, poorly differentiated adenocarcinoma in two cases [...](AU)

Survival and disease-free interval of cats with mammary carcinoma treated with chain mastectomy

Background: Mammary tumors are extremely common in cats and have high metastatic rates with poor prognosis. The main objective of the present study was to evaluate the disease free interval and survival in cats undergoing radical mastectomy as sole therapy. Materials, Methods & Results: Twenty cats with mammary tumors and no evidence of distant metastasis were studied. General health and concomitant diseases were assessed by clinical and hematological examination. Thoracic radiographs and abdominal ultrasonography were performed to evaluate thoracic and abdominal metastases. All cats underwent chain mastectomy, which was unilateral when tumor was present in one mammary chain, and bilateral in steps if tumors were present in both mammary chains. Intact cats were spayed. An elliptical incision was made around the mammary chain with a three centimeter margin around tumor. Regional lymph node was removed. Mean age was ten years, and 14 cats were mixed breed, three were Persian and two were Siamese. Fifteen cats were spayed at tumor diagnosis, but only three had been spayed before one year old. The inguinal mammary glands were the most affected, followed by abdominal and thoracic glands. Histopathology diagnosed well-differentiated adenocarcinoma in eight cases, moderately differentiated adenocarcinoma in nine cases, poorly differentiated adenocarcinoma in two cases [...]

Utilização de imiquimode creme 5% no tratamento de placa aural em um equino: relato de caso / Use of Imiquimod 5% cream in the treatment of aural plaque in a horse: case report / Utilización de imiquimode crema 5% en el tratamiento de la placa aural en um equino: estudio de caso

A placa aural é uma lesão de pele que acomete a face interna da orelha de equinos, independente de raça, idade ou sexo. São lesões bem delimitadas, esbranquiçadas, únicas ou múltiplas, com hiperqueratose.É causada pelo Equus caballus papillomavírus tipos 3 e 4. Os animais podem apresentar-se sem sintomatologia clínica. O tratamento é indicado quando há presença de sensibilidade da orelha ao toque e à colocação de cabrestos e freios e animais destinados à provas de morfologia. O Imiquimode é um imunomodulador que induz uma reação inflamatória caracterizada pela liberação de mediadores químicos. Este trabalho tem por objetivo descrever a utilização de imiquimode creme 5% no tratamento da placa aural de um equino. Houve remissão total em uma orelha e recidiva na outra. O tratamento foi seguro, apesar das recidivas apresentadas.

Aural plaque is a skin disease that affects the internal face of equine ears, independently of breed,age or sexoThey are well delimited, white colored, single or multiple lesions with hiper keratosis. It is caused by Equus caballus papillomavirus types 3 and 4. In Brazil, there is a low prevalence of the disease, differently ofthe prevalence found in Europe that is about of 15%. No treatment is required if animais are asymptomatic butin those for exhibitions, it may be performed. Treatment is indicated for animais that have sensible ears andshow reluctance in wearing halters and brakes. Imiquimod is an immune response modifier, used in humanmedicine, that induces an inflammatory reaction characterized by release of chemical mediators. The aim of the present study was to describe the use of Imiquimod 5% cream in the treatment of aural plaque oin one equine. There was total remission in one ear and recurrence in another. Treatment with Imiquimod 5% creamwas safe, although recurrence was observed.

La placa aural es una afección de Ia face interna de Ias orejas de equinos, independiente de Iaraza, edad o sexo. Son lesiones bien definidas, de color blanco, únicas o múltiplas, y hiperkeratosis. Laafección es causada por 105Equus caballus papillomavírus tipos 3 y 4. Algunos caballos pueden no presentar sintomatología clínica y portanto, no se hace tratamiento, solo para animales asignados a Ias pruebas debelleza y conformación. EI tratamiento es indicado para animales sensibles a colocación de cabestros y frenos. EI imiquimode es un imunomodulador, utilizado hace mucho tiempo en Ia medicina humana, e inducea una reacción inflamatoria caracterizada por Ia liberación de mediadores químicos quimiotácticos. EI objetivo dei presente trabajo es describir Ia utilización de imiquimode crema 5% en el tratamiento de Ia placa aural. Hubo remisión total en una oreja y recaída en outra. EI tratamiento de placa aural utilizándose imiquimode crema 5% es seguro, a pesar de Ias recaídas presentadas.

Utilização de imiquimode creme 5% no tratamento de placa aural em um equino: relato de caso / Use of Imiquimod 5% cream in the treatment of aural plaque in a horse: case report / Utilización de imiquimode crema 5% en el tratamiento de la placa aural en um equino: estudio de caso

A placa aural é uma lesão de pele que acomete a face interna da orelha de equinos, independente de raça, idade ou sexo. São lesões bem delimitadas, esbranquiçadas, únicas ou múltiplas, com hiperqueratose.É causada pelo Equus caballus papillomavírus tipos 3 e 4. Os animais podem apresentar-se sem sintomatologia clínica. O tratamento é indicado quando há presença de sensibilidade da orelha ao toque e à colocação de cabrestos e freios e animais destinados à provas de morfologia. O Imiquimode é um imunomodulador que induz uma reação inflamatória caracterizada pela liberação de mediadores químicos. Este trabalho tem por objetivo descrever a utilização de imiquimode creme 5% no tratamento da placa aural de um equino. Houve remissão total em uma orelha e recidiva na outra. O tratamento foi seguro, apesar das recidivas apresentadas.(AU)

Aural plaque is a skin disease that affects the internal face of equine ears, independently of breed,age or sexoThey are well delimited, white colored, single or multiple lesions with hiper keratosis. It is caused by Equus caballus papillomavirus types 3 and 4. In Brazil, there is a low prevalence of the disease, differently ofthe prevalence found in Europe that is about of 15%. No treatment is required if animais are asymptomatic butin those for exhibitions, it may be performed. Treatment is indicated for animais that have sensible ears andshow reluctance in wearing halters and brakes. Imiquimod is an immune response modifier, used in humanmedicine, that induces an inflammatory reaction characterized by release of chemical mediators. The aim of the present study was to describe the use of Imiquimod 5% cream in the treatment of aural plaque oin one equine. There was total remission in one ear and recurrence in another. Treatment with Imiquimod 5% creamwas safe, although recurrence was observed.(AU)

La placa aural es una afección de Ia face interna de Ias orejas de equinos, independiente de Iaraza, edad o sexo. Son lesiones bien definidas, de color blanco, únicas o múltiplas, y hiperkeratosis. Laafección es causada por 105Equus caballus papillomavírus tipos 3 y 4. Algunos caballos pueden no presentar sintomatología clínica y portanto, no se hace tratamiento, solo para animales asignados a Ias pruebas debelleza y conformación. EI tratamiento es indicado para animales sensibles a colocación de cabestros y frenos. EI imiquimode es un imunomodulador, utilizado hace mucho tiempo en Ia medicina humana, e inducea una reacción inflamatoria caracterizada por Ia liberación de mediadores químicos quimiotácticos. EI objetivo dei presente trabajo es describir Ia utilización de imiquimode crema 5% en el tratamiento de Ia placa aural. Hubo remisión total en una oreja y recaída en outra. EI tratamiento de placa aural utilizándose imiquimode crema 5% es seguro, a pesar de Ias recaídas presentadas.(AU)