Histopathological pattern recognition of cresty neck in horses in Spain

The aim of this study was to describe patterns of histopathological recognition of the cresty neck in Horses in Spain. A total of 250 horses were studied in Andalusia and Extremadura, Spain. Seventy-six percent of horses present cresty neck. The damage of the cresty neck in horses was categorized as Grade 0 - Muscle fibers are observed, no fat vacuoles are observed (24% of the horses). Grade 1 - Scarce adipose deposit was observed. An unaltered muscle tissue is observed (21% of the horses). Grade 2 - fat vacuoles are evident in muscle tissue intermyofibrillar space and prone to coalescence (23% of the horses). Grade 3 - Abundant fat vacuoles in the intermyofibrillar space, with tendency to coalesce, and low fat infiltration in muscle tissue (moderate lipomatosis) (16% of the horses). Grade 4 - Abundant fat vacuoles in the intermyofibrillar space, with tendency to coalesce, and fatty infiltration in muscle tissue (marked lipomatosis) (8% of the horses). Grade 5 - Only fat vacuoles are observed, without muscle tissue (severe lipomatosis) (8% of the horses). The results for desmin antibody (1: 100 dilution) was positive (++) in grades 0-2, and negative (-) in grades 3-5. These results suggest that as fat/lipomatosis infiltration increases (progresses in grades 3, 4 and 5), the intercellular space (intermyofibrillar) increases and therefore the cell cytoskeleton is lost, with loss of the bands Z, so the negative response to this antibody. Inconclusion, we describe histopathological pattern recognition of cresty neck in horses in Spain.

Histopathological pattern recognition of cresty neck in horses in Spain

The aim of this study was to describe patterns of histopathological recognition of the cresty neck in Horses in Spain. A total of 250 horses were studied in Andalusia and Extremadura, Spain. Seventy-six percent of horses present cresty neck. The damage of the cresty neck in horses was categorized as Grade 0 - Muscle fibers are observed, no fat vacuoles are observed (24% of the horses). Grade 1 - Scarce adipose deposit was observed. An unaltered muscle tissue is observed (21% of the horses). Grade 2 - fat vacuoles are evident in muscle tissue intermyofibrillar space and prone to coalescence (23% of the horses). Grade 3 - Abundant fat vacuoles in the intermyofibrillar space, with tendency to coalesce, and low fat infiltration in muscle tissue (moderate lipomatosis) (16% of the horses). Grade 4 - Abundant fat vacuoles in the intermyofibrillar space, with tendency to coalesce, and fatty infiltration in muscle tissue (marked lipomatosis) (8% of the horses). Grade 5 - Only fat vacuoles are observed, without muscle tissue (severe lipomatosis) (8% of the horses). The results for desmin antibody (1: 100 dilution) was positive (++) in grades 0-2, and negative (-) in grades 3-5. These results suggest that as fat/lipomatosis infiltration increases (progresses in grades 3, 4 and 5), the intercellular space (intermyofibrillar) increases and therefore the cell cytoskeleton is lost, with loss of the bands Z, so the negative response to this antibody. Inconclusion, we describe histopathological pattern recognition of cresty neck in horses in Spain.(AU)

Infiltrative Lipomatosis in the Neck and Colon of a Spanish Pure Breed Horse

The aim of this study was to report a case of infiltrative lipomatosis in the neck and colon in a horse. A 12-year-old male Spanish Pure Breed Horse with deformation of dorsal neck, weighing 650 kg, with a history of acute colic for approximately 24 hours. Euthanasia was undertaken. A necropsy revealed general excessive lipid accumulation in subcutaneous tissue in the dorsal neck. The pelvic flexure of the large colon was found to be displaced into the right cranial abdomen. A large multinodular and multifocal infiltrative fatty mass coalescing was present in a 1.5 m segment of colon with severed lipomatosis; the small intestine proximal to this lesion was moderately distended with fluid. Lipomatosis in the dorsal neck was observed, characterized by diffuse thickening of the subcutis by mature adipose tissue. In conclusion we report a case of severed infiltrative lipomatosis intestinal in large colon and neck.

Infiltrative Lipomatosis in the Neck and Colon of a Spanish Pure Breed Horse

The aim of this study was to report a case of infiltrative lipomatosis in the neck and colon in a horse. A 12-year-old male Spanish Pure Breed Horse with deformation of dorsal neck, weighing 650 kg, with a history of acute colic for approximately 24 hours. Euthanasia was undertaken. A necropsy revealed general excessive lipid accumulation in subcutaneous tissue in the dorsal neck. The pelvic flexure of the large colon was found to be displaced into the right cranial abdomen. A large multinodular and multifocal infiltrative fatty mass coalescing was present in a 1.5 m segment of colon with severed lipomatosis; the small intestine proximal to this lesion was moderately distended with fluid. Lipomatosis in the dorsal neck was observed, characterized by diffuse thickening of the subcutis by mature adipose tissue. In conclusion we report a case of severed infiltrative lipomatosis intestinal in large colon and neck.(AU)

Obstrução intestinal por necrose massiva de gordura abdominal (lipomatose) em uma vaca Jersey / Intestinal obstruction due to massive fat necrosis (lipomatosis) in a Jersey cow

Uma fêmea da raça Jersey com 9 anos de idade apresentou cólicas e dificuldade de defecação progressiva que evoluiu até completa obstrução intestinal. O animal morreu uma semana após uma tentativa infrutífera de corrigir cirurgicamente a obstrução. Na necropsia, as alças intestinais estavam distendidas por acúmulo de cont aeúdo fecal e havia massas de gordura necrótica circundando o segmento final do intestino. Os achados histológicos foram necrose da gordura associada à fibrose intersticial, inflamação crônica com células gigantes tipo corpo estranho, fendas de colesterol e mineralização.(AU)

A 9 year-old Jersey cow showed a clinical picture that initiated with colic, small amounts of feces, and progressed to the complete obstruction of the intestinal passage. The cow died one week after an unsuccessful cirurgic attempt to correct obstruction. At necropsy, the intestinal loops were distended by content accumulation and there were masses of necrotic fat surrounding the final segment of the intestine. The histological findings were fatty necrosis associated with interstitial fibrosis, chronic inflammation with foreign body type giant cells, cholesterol clefts and mineralization.(AU)