Ocorrência de adenocarcinoma endometrial em Oryctolagus cuniculus (Linnaeus, 1758): Relato de caso / Occurrence of endometrial adenocarcinoma in Oryctolagus cuniculus (Linnaeus, 1758): Case report

Endometrial adenocarcinoma is often view in rabbits at older age, disabling them for reproduction. Thepresente work aim to report the occurrence of endometrial adenocarcinoma in Oryctolagus cuniculus, in the cityof Belém, Pará. The animal come to death and it was referred for the performance of its necropsy, thereproductive tract was fixed in formaldehyde to continue the histopathological examination. Grossly, it wasverified that the uterine horn exhibited a dilated segment, vascularised and with friable tissue. Microscopicallyit was noticed tubular pattern formation with luminal expansion, anisocytosis, anisonucleosis and low mitoticrates. Then, due to the pathological characteristics, it suggests an occurrence of endometrial adenocarcinomain rabbits.(AU)

Ocorrência de adenocarcinoma endometrial em Oryctolagus cuniculus (Linnaeus, 1758): Relato de caso / Occurrence of endometrial adenocarcinoma in Oryctolagus cuniculus (Linnaeus, 1758): Case report

Endometrial adenocarcinoma is often view in rabbits at older age, disabling them for reproduction. Thepresente work aim to report the occurrence of endometrial adenocarcinoma in Oryctolagus cuniculus, in the cityof Belém, Pará. The animal come to death and it was referred for the performance of its necropsy, thereproductive tract was fixed in formaldehyde to continue the histopathological examination. Grossly, it wasverified that the uterine horn exhibited a dilated segment, vascularised and with friable tissue. Microscopicallyit was noticed tubular pattern formation with luminal expansion, anisocytosis, anisonucleosis and low mitoticrates. Then, due to the pathological characteristics, it suggests an occurrence of endometrial adenocarcinomain rabbits.

Adenocarcinoma endometrial em uma coelha (Oryctolagus cuniculus) / Endometrial adenocarcinoma in a rabbit (Oryctolagus cuniculus)

Background: Uterine tumors are classified according to their origin, epithelial or mesenchymal. These neoplasms are uncommon in most animal species, but are considered as important causes of reproductive disorders. In rabbits, the occurrence of these tumors increase with development of the animals and, although the numbers indicate a high occurrence of this disease in rabbits, reports are scarce. Therefore, this paper has the objective to describe a case of endometrial adenocarcinoma in a rabbit, emphasizing their histological features as well as provide a brief discussion about the epidemiological, clinical, pathological and prevention forms and treatment. Case: A 4-years old New Zealand rabbit breed, from a group of animals maintained only for breeding, had low fertility. The rabbit was twice covered by proven fertile animals, but no pregnancy, becoming unfit reproduction and subjected to euthanasia. At necropsy, tissue samples were collected, subsequently fixed in 10% formalin and then were processed routinely and stained with hematoxylin and eosin for histopathological analysis. Grossly, there was swelling of the uterine body, characterized by two masses that protruded from the endometrium, with rounded and soft look, and the court had cystic cavity filled with whitish gelatinous consistency of content. Microscopic cancer cells that originated from the endometrial...(AU)

Adenocarcinoma endometrial em uma coelha (Oryctolagus cuniculus) / Endometrial adenocarcinoma in a rabbit (Oryctolagus cuniculus)

Background: Uterine tumors are classified according to their origin, epithelial or mesenchymal. These neoplasms are uncommon in most animal species, but are considered as important causes of reproductive disorders. In rabbits, the occurrence of these tumors increase with development of the animals and, although the numbers indicate a high occurrence of this disease in rabbits, reports are scarce. Therefore, this paper has the objective to describe a case of endometrial adenocarcinoma in a rabbit, emphasizing their histological features as well as provide a brief discussion about the epidemiological, clinical, pathological and prevention forms and treatment. Case: A 4-years old New Zealand rabbit breed, from a group of animals maintained only for breeding, had low fertility. The rabbit was twice covered by proven fertile animals, but no pregnancy, becoming unfit reproduction and subjected to euthanasia. At necropsy, tissue samples were collected, subsequently fixed in 10% formalin and then were processed routinely and stained with hematoxylin and eosin for histopathological analysis. Grossly, there was swelling of the uterine body, characterized by two masses that protruded from the endometrium, with rounded and soft look, and the court had cystic cavity filled with whitish gelatinous consistency of content. Microscopic cancer cells that originated from the endometrial...