Resumo

Background: Digestive disturbances in ruminants are associated with forage shortages during periods of dry weather. Foodsavailable at this time are generally of poor quality and low digestibility, which makes it necessary to pursue alternativefood sources where available. Grain-heavy diets; concentrated rations rich in rapidly fermenting carbohydrates; and whey,tubers and fruits high in starch and glucose, contribute to ruminal acidosis. Here we report a case of ruminal acidosis dueto excessive ingestion of the mango fruit (Mangifera indica), “manguita” cultivate, by an adult bovine.Case: In the municipality of Boa Vista, Roraima, during December, a Dutch female bovine adult, weighing approximately600 kg, was observed showing signs of apathy for two days with diarrhea. The animal had a rumenostomy with flexiblecannula in the left paralumbar fossa and was in the final third of gestation. During clinical examination, the animal was inseason, and an increase in the volume of the left dorsal region and changes in physiological variables were observed (lightlypale mucosa, capillary filling time of 4 s, heart rate [HR] of 82 beats per min; respiratory rate (f) of 30 moments per min;absence of ruminal movements and rectal temperature [RT] of 39.5°C). Upon removal of the cannula lid, a considerableamount of liquid and a large quantity of mango (Mangifera indica), “manguita” cultivate, were observed. Blood sampleand ruminal fluid were collected and ruminal contents weighing approximately 40 kg were evacuated. Physical-chemicalanalysis of the ruminal liquid (pH = 4.0, brown color, aqueous consistency and characteristic fruit odor) resulted in adiagnosis of ruminal acidosis. Treatment included administration of fluid therapy (Lactate Ringer; 2 mL/kg/h), hepatoprotector (1 mL/20 kg), antimicrobial (Ampicillin Sodium; 10 mg/kg/IV and Sulfadoxine; 30 mg/kg/IV) and non-steroidalanti-inflammatory (Meloxicam; 0.5 mg/kg/IV) drugs, associated with evacuation...

Resumo

Foram utilizados seis novilhos, providos de cânula ruminal, em delineamento experimental cross-over, para comparar a eficiência de soluções de bicarbonato de sódio e lactato-L de sódio na correção da acidose metabólica sistêmica (AMS), causada pela acidose láctica ruminal (ALR). Vinte horas após, quando apresentavam intensa AMS, os animais foram distribuídos aleatoriamente e tratados com cinco litros de 150mMol/l de bicarbonato de sódio ou de lactato-L de sódio, infundidas por via intravenosa, nas quatro horas seguintes. Amostras de sangue, para hemogasometria, foram coletadas no decorrer da infusão a zero, 1, 2, 3, 4, 6 e 8 horas. Ambos os tratamentos elevaram o pH sangüíneo já na primeira hora pós-infusão, corrigindo adequadamente a AMS. O tratamento com lactato-L de sódio aumentou as concentrações de bicarbonato, TCO2 e EAB sangüíneos já na segunda hora pós-infusão; com o bicarbonato essa elevação ocorreu a partir da terceira hora. Não houve diferenças entre tratamentos para pH sangüíneo, bicarbonato, TCO2 e excesso de base. Vinte e quatro horas após o tratamento todos os novilhos apresentaram plena recuperação. O lactato-L pode substituir o bicarbonato na correção da AMS em novilhos com ALR

The efficiency of sodium bicarbonate or l-lactate for correcting systemic metabolic acidosis (SMA) caused by rumen lactic acidosis (RLA) was evaluated using six rumen-cannulated steers in a cross-over experimental design. RLA was induced by administration of sucrose, intraruminally. Twenty hours later when the animals developed an intense SMA, the steers were randomly distributed and treated intravenously either with 5l of 15 mMol/l sodium bicarbonate or L-lactate solution, infused throughout 4h. Blood samples were colleted throughout the infusion at zero, 1, 2, 3, 4, 6 and 8h, for blood gas analysis. After 1hour, both sodium bicarbonate and L-lactate solutions increased blood pH and corrected adequately the SMA. Blood bicarbonate, TCO2 and base excess concentrations were also increased at the 2nd hour with L-lactate and at the 3rd hour with bicarbonate. No differences between treatments were observed for blood pH, bicarbonate, TCO2 and base excess concentrations. Treated steers after twenty-four hours showed an effective clinical recovery. L-lactate can adequately replace bicarbonate in the correction of SMA in steers with RLA

Resumo

Seis novilhos mestiços, com cerca de 250kg e um ano de idade, foram infundidos, no decorrer de quatro horas, com cinco litros de diferentes soluções isotônicas de sais sódicos, com 150mM/l de bicarbonato, acetato, propionato, lactato L, lactato racêmico e cloreto (controle), em delineamento em quadrado latino (6x6). Análises hemogasométricas e do pH urinário foram determinadas no decorrer da infusão - zero, primeira e quatro horas - e após o seu término, na oitava hora. O pH do sangue foi maior nos animais infundidos com os tampões que nos infundidos com cloreto; teores mais elevados de bicarbonato e de excesso de ácido-base sanguíneos foram obtidos na quarta e oitava hora nos infundidos com bicarbonato e lactato; o mesmo ocorreu com a pressão de CO2 na oitava hora. Os resultados indicam que os tratamentos com Bicarbonato e lactato proporcionam acúmulo de tampões no sangue e geram discreta alcalose metabólica, compensada organicamente por leve retenção de CO2. a infusão com bicarbonato de sódio causa elevação do pH urinário

Six healthy crossbred yearling 250kg steers were infused intravenously, during four hours, with five liters of each of the six different isotonic solutions of sodium salts containing 150 mMol/l of the bicarbonate, acetate, propionate, L-lactate, D and L-lactate and chloride in a 6 x 6 latin square experimental design. Blood was collected from the jugular vein, anaerobically, for blood gas analysis, samples were obtained at different times throughout the infusion (zero, 1st, 4th and 8th h ). Urine was collect for determining the pH at the same schedule. Higher blood pH was found in cattle infused with all buffers than the chloride infused animals; higher level of blood bicarbonate and base excess were obtained at 4th and 8th h with bicarbonate and L-lactate, as well as with pCO2 at the 8th h. These results show that treatments with B and L lead to a slight accumulation of buffers in the blood, and generate a discrete metabolic alkalosis compensated organically by a small retention of CO2. Best alkalinizing effects are obtained by bicarbonate and L-lactato infusions. Bicarbonate infusions causes a high urinary pH