Utilização da ozonioterapia como tratamento da endometrite em égua / Use of ozone therapy as endometritis treatment in mare

Conformações perineais inadequadas estão frequentemente associadas à pneumovagina, predispondo animais a processos inflamatórios vaginais e uterinos. Dentre as patologias reprodutivas que acometem éguas, a endometrite é a que ocorre com maior frequência, com forte impacto negativo sobre os índices reprodutivos de um criatório. Para essa afecção, a ozonioterapia se apresenta como tratamento em potencial. Assim, este estudo objetiva relatar um caso de endometrite em égua Quarto de Milha, multípara, de 17 anos de idade, atendida no Hospital Veterinário Sylvio Barbosa Cardoso, da Universidade Estadual de Ceará. Durante a avaliação ginecológica, observou-se alterações na conformação vulvar e teste de Windsucker positivo, indicando pneumovagina. Foram coletadas amostras endometriais para exames laboratoriais, os quais apresentaram citologia com contagem de neutrófilos polimorfonucleares ≥30% e cultura negativa para fungos e bactérias. O exame histopatológico revelou fibrose intersticial endometrial crônica acentuada. Diante do diagnóstico de endometrite, iniciou-se o tratamento com lavagem uterina usando solução ringer lactato ozonizada, seguido por insuflação uterina com ozônio. O animal foi submetido à técnica cirúrgica de Caslick para correção da má conformação vulvar. Após o tratamento, a égua foi inseminada, resultando na coleta de dois embriões viáveis. Diante do exposto, o caso reforça a efetividade da ozonioterapia associada à Caslick para o tratamento de endometrite em éguas.

Dysfunctional perineal conformations are often associated with pneumovagina, predisposing animals to vaginal and uterine inflammatory processes. Among the reproductive pathologies that affect mares, endometritis is the most frequent, with a strong negative impact on the reproductive indices of a farm. For this condition, ozone therapy presents itself as a potential treatment. The study aimed to report a case of endometritis in a 17-year-old multiparous quarter-mile mare, which was attended at the Veterinary Hospital Sylvio Barbosa Cardoso located in the State University of Ceará. During the gynecological evaluation, changes in vulvar conformation and a positive Windsucker test were observed, indicating pneumovagina. Endometrial samples were collected for laboratory exams, resulting in cytology with polymorphonuclear neutrophil count ≥30% and negative culture for fungi and bacteria. The histopathological examination revealed severe chronic endometrial interstitial fibrosis. Regarding the diagnosis of endometritis, the treatment with uterine lavage using ozonated ringer lactate solution was initiated followed by uterine insufflation with ozone. The animal was submitted to Caslick's surgical technique to correct the vulvar malformation. After treatment, the mare was inseminated, resulting in the collection of two viable embryos. In view of the above, the case reinforces the effectiveness of ozone therapy associated with Caslick`s technique for endometritis treatment in mares.

Acute effect of whole-body vibration in a female dog with metritis

Background: Whole-body vibration is a modality of exercise used in humans for therapeutic purposes or to increase physical performance. In veterinary medicine there are only a few reports on the use of this technology. The Whole-body vibration derivate from vibrating rhythmic movements caused by vibrating platforms. Vibrating platforms are used over 30 years in the treatment and prevention of injuries and other debilitating conditions in humans. This paper aims to describe the first report of a possible spontaneous opening of the cervix in a female dog with purulent metritis by Whole-body vibration using a platform vibration.Case: A sexually intact female American Pit Bull Terrier dog showed an acute effect after a single session of Wholebody vibration training. Physical examination and physiological parameters were within normal. Slight edema of the vulva was observed without signs of discharge. Complete blood cell count, serum chemistry and urinalysis yielded no significant abnormal findings. An enlarged uterus with content was observed during a transabdominal ultrasound. Despite this, a vibrating-platform session was performed during 15 min. A purulent vulvar discharge was observed 6 min. after Whole-body vibration exercise and remained continuous through session. After the Whole-body vibration exercise, the dog was treated with cephalexin for 15 days. Escherichia coli were [...]

Acute effect of whole-body vibration in a female dog with metritis

Background: Whole-body vibration is a modality of exercise used in humans for therapeutic purposes or to increase physical performance. In veterinary medicine there are only a few reports on the use of this technology. The Whole-body vibration derivate from vibrating rhythmic movements caused by vibrating platforms. Vibrating platforms are used over 30 years in the treatment and prevention of injuries and other debilitating conditions in humans. This paper aims to describe the first report of a possible spontaneous opening of the cervix in a female dog with purulent metritis by Whole-body vibration using a platform vibration.Case: A sexually intact female American Pit Bull Terrier dog showed an acute effect after a single session of Wholebody vibration training. Physical examination and physiological parameters were within normal. Slight edema of the vulva was observed without signs of discharge. Complete blood cell count, serum chemistry and urinalysis yielded no significant abnormal findings. An enlarged uterus with content was observed during a transabdominal ultrasound. Despite this, a vibrating-platform session was performed during 15 min. A purulent vulvar discharge was observed 6 min. after Whole-body vibration exercise and remained continuous through session. After the Whole-body vibration exercise, the dog was treated with cephalexin for 15 days. Escherichia coli were [...](AU)

Células Tronco Mesenquimais De Tecido Adiposo Bovino: Uma Opção De Tratamento Para Endometrite? / Mesenchymal Stem Cells From Bovine Adipose Tissue: A Treatment Option For Endometritis? / Células Troncal Mesenquimales De Tejido Adiposo Bovino: Una Opción De Tratamiento Para Endometritis?

A endometrite em bovinos possui grande prevalência na bovinocultura brasileira, gerando aumento no intervalo entre partos, diminuindo produtividade e causando prejuízos no setor agropecuário. O uso de terapia celular é de grande utilidade na medicina regenerativa e biotecnologia animal. Avanços nesta esfera abrangem cada vez mais áreas de atuação desta terapia. O objetivo deste trabalho foi revisar a literatura acerca de endometrite em bovinos e a possível aplicabilidade de células tronco mesenquimais oriundas de tecido adiposo como terapia. Conclui-se que a terapia celular em casos de endometrite em bovinos é um campo promissor, capaz de agir na imunomodulação local.(AU)

Endometritis in cattle has a high prevalence in Brazilian cattle farming, increasing the interval between calving, reducing productivity and causing losses in the agricultural sector. The use of cell therapy is of great utility in regenerative medicine and animal biotechnology. Advances in this sphere cover more and more areas of action of this therapy. The objective of this work was to review the literature on endometritis in cattle and the possible applicability of mesenchymal stem cells derived from adipose tissue as therapy. It is concluded that the cell therapy in cases of endometritis in cattle is a promising field, capable of acting in the local immunomodulation.(AU)

La endometritis en bovinos posee gran prevalencia en la bovinocultura brasileña, generando aumento en el intervalo entre partos, disminuyendo productividad y causando perjuicios en el sector agropecuario. El uso de terapia celular es de gran utilidad en la medicina regenerativa y la biotecnología animal. Los avances en esta esfera abarca cada vez más áreas de actuación de esta terapia. El objetivo de este trabajo fue revisar la literatura acerca de endometritis en bovinos y la posible aplicabilidad de células madre mesenquimales oriundas de tejido adiposo para terapia. Se concluye que la terapia celular en casos de endometritis en bovinos es un campo prometedor, capaz de actuar en la inmunomodulación local.(AU)

Células Tronco Mesenquimais De Tecido Adiposo Bovino: Uma Opção De Tratamento Para Endometrite? / Mesenchymal Stem Cells From Bovine Adipose Tissue: A Treatment Option For Endometritis? / Células Troncal Mesenquimales De Tejido Adiposo Bovino: Una Opción De Tratamiento Para Endometritis?

A endometrite em bovinos possui grande prevalência na bovinocultura brasileira, gerando aumento no intervalo entre partos, diminuindo produtividade e causando prejuízos no setor agropecuário. O uso de terapia celular é de grande utilidade na medicina regenerativa e biotecnologia animal. Avanços nesta esfera abrangem cada vez mais áreas de atuação desta terapia. O objetivo deste trabalho foi revisar a literatura acerca de endometrite em bovinos e a possível aplicabilidade de células tronco mesenquimais oriundas de tecido adiposo como terapia. Conclui-se que a terapia celular em casos de endometrite em bovinos é um campo promissor, capaz de agir na imunomodulação local.

Endometritis in cattle has a high prevalence in Brazilian cattle farming, increasing the interval between calving, reducing productivity and causing losses in the agricultural sector. The use of cell therapy is of great utility in regenerative medicine and animal biotechnology. Advances in this sphere cover more and more areas of action of this therapy. The objective of this work was to review the literature on endometritis in cattle and the possible applicability of mesenchymal stem cells derived from adipose tissue as therapy. It is concluded that the cell therapy in cases of endometritis in cattle is a promising field, capable of acting in the local immunomodulation.

La endometritis en bovinos posee gran prevalencia en la bovinocultura brasileña, generando aumento en el intervalo entre partos, disminuyendo productividad y causando perjuicios en el sector agropecuario. El uso de terapia celular es de gran utilidad en la medicina regenerativa y la biotecnología animal. Los avances en esta esfera abarca cada vez más áreas de actuación de esta terapia. El objetivo de este trabajo fue revisar la literatura acerca de endometritis en bovinos y la posible aplicabilidad de células madre mesenquimales oriundas de tejido adiposo para terapia. Se concluye que la terapia celular en casos de endometritis en bovinos es un campo prometedor, capaz de actuar en la inmunomodulación local.

Therapeutics for Infectious Endometritis: A Clinical Perspective / Opções terapêuticas nas endometrites infecciosas

There are multiple options for treatment of infections endometritis. For simple acute cases of bacterialendometritis simple intrauterine antibiotic therapy is often effective. However in chronic cases of bacterial andfungal endometritis the use of both systemic and local therapy can help with clearance of these difficultinfections.(AU)

Therapeutics for Infectious Endometritis: A Clinical Perspective / Opções terapêuticas nas endometrites infecciosas

There are multiple options for treatment of infections endometritis. For simple acute cases of bacterialendometritis simple intrauterine antibiotic therapy is often effective. However in chronic cases of bacterial andfungal endometritis the use of both systemic and local therapy can help with clearance of these difficultinfections.