Polycystic kidney disease in rough toothed dolphins (Steno bredanensis) found in the Paraná coast, southern Brazil

Background: Renal cystic diseases (RCD) are characterized by cystic structures on renal parenchyma associated withobstructive lesions, membranous disruptions, and/or growth disturbances. The polycystic kidney disease (PKD) showsspecific pathological characteristics, related to mutations on PKD1 and/or PKD2 chromosome locus on humans. In Persiancats and bull terriers the condition is like the human “adult-onset” PKD, while in Perendale sheep the “childhood”-like isdescribed. In cetaceans, RCD are reported, however the characterization of PKD is scarcely described. This report aimsto describe two cases of PKD and one of RCD in stranded Steno bredanensis, and to discuss the disease associated factors.Cases: Four rough-toothed-dolphins were found stranded in the Paraná coast, southern Brazil between 2016 to 2018,through the Santos Basin Beach Monitoring Project (PMP-BS), one of the systematic monitoring programs required byBrazilian Institute of Environment and Renewable Natural Resources (IBAMA) for the environmental licensing processof oil production and transport by Petrobras in the presalt province. In three animals histological sampling was performed.One of them (animal 3) was found alive, presenting altered buoyancy with lateralization to the right and signs of pneumonia. The blood analysis showed anemia and leukocytosis. The animal showed poor clinical prognosis, and even withsupportive treatment, come to death four days after the rescue. Routine autopsies were performed on all animals. Animals1 and 2 presented macroscopically enlarged kidneys containing disseminated cystic...

Polycystic kidney disease in rough toothed dolphins (Steno bredanensis) found in the Paraná coast, southern Brazil

Background: Renal cystic diseases (RCD) are characterized by cystic structures on renal parenchyma associated withobstructive lesions, membranous disruptions, and/or growth disturbances. The polycystic kidney disease (PKD) showsspecific pathological characteristics, related to mutations on PKD1 and/or PKD2 chromosome locus on humans. In Persiancats and bull terriers the condition is like the human “adult-onset” PKD, while in Perendale sheep the “childhood”-like isdescribed. In cetaceans, RCD are reported, however the characterization of PKD is scarcely described. This report aimsto describe two cases of PKD and one of RCD in stranded Steno bredanensis, and to discuss the disease associated factors.Cases: Four rough-toothed-dolphins were found stranded in the Paraná coast, southern Brazil between 2016 to 2018,through the Santos Basin Beach Monitoring Project (PMP-BS), one of the systematic monitoring programs required byBrazilian Institute of Environment and Renewable Natural Resources (IBAMA) for the environmental licensing processof oil production and transport by Petrobras in the presalt province. In three animals histological sampling was performed.One of them (animal 3) was found alive, presenting altered buoyancy with lateralization to the right and signs of pneumonia. The blood analysis showed anemia and leukocytosis. The animal showed poor clinical prognosis, and even withsupportive treatment, come to death four days after the rescue. Routine autopsies were performed on all animals. Animals1 and 2 presented macroscopically enlarged kidneys containing disseminated cystic...(AU)

Gastric Braunina cordiformis and a review of helminth parasitism in the finless porpoise (Neophocaena phocaenoides)

A pregnant adult female finless porpoise (Neophocaena phocaenoides) stranded off the coast of Phuket, Thailand and died during attempted rehabilitation. The cadaver was frozen for use in a Marine mammal stranding training event. During necropsy, the animal was observed to have approximately 60% of the gastric mucosa embedded with exophytic, heart shaped digenean trematodes interpreted to be Braunina cordiformis. Tissue samples were collected from the stomach to include the embedded parasites and these were evaluated histopathologically, confirming the diagnosis. This is the first report of Braunina cordiformis trematodes in Asian waters and the first report of the parasite in a finless porpoise.

Gastric Braunina cordiformis and a review of helminth parasitism in the finless porpoise (Neophocaena phocaenoides)

A pregnant adult female finless porpoise (Neophocaena phocaenoides) stranded off the coast of Phuket, Thailand and died during attempted rehabilitation. The cadaver was frozen for use in a Marine mammal stranding training event. During necropsy, the animal was observed to have approximately 60% of the gastric mucosa embedded with exophytic, heart shaped digenean trematodes interpreted to be Braunina cordiformis. Tissue samples were collected from the stomach to include the embedded parasites and these were evaluated histopathologically, confirming the diagnosis. This is the first report of Braunina cordiformis trematodes in Asian waters and the first report of the parasite in a finless porpoise.(AU)