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1.
Braz. J. Vet. Res. Anim. Sci. (Online) ; 56(1): e146549, jun. 2019. ilus
Artigo em Inglês | LILACS, VETINDEX | ID: biblio-1008027

Resumo

Neuropathies of pharyngeal branches of glossopharyngeal and vagus are often associated with guttural pouches diseases; however, these branches of injury due to stylopharyngeus muscle compression are not reported. A case was reported of a quarter horse mare, 8 years old, 450 kg, presenting dyspnea and respiratory noise associated with weight loss. Clinical examination observed mixed dyspnea, tachycardia, dysphagia, sialorrhea, lung crackles and submandibular and parotid lymphadenopathy. Endoscopic exam showed right arytenoid chondritis, nasopharyngeal collapse, generalized larynx edema and dorsal displacement of the soft palate. Right guttural pouch evaluation showed swelling in the origin of stylopharyngeus muscle with consequent compression of the XII, X and IX cranial nerves. Tracheotomy, systemic treatment with corticosteroids, beta lactams and aminoglycosides antibiotics were performed. No resolution was observed and, after 16 days, the animal showed clinical worsening, developed pleuropneumonia, uveitis, severe sepsis, acute renal failure and was euthanized. The mixed neuropathy resulted in rapid clinical deterioration of the animal, due to the difficulty in swallowing and consequent associated respiratory processes. This report emphasizes the importance of evaluating stylopharyngeus muscle origin in cases of nasopharyngeal collapse associated with dysphagia in horses, given the possibility that structural changes in this muscle can result in laryngeal neuropathy.(AU)


As neuropatias do glossofaríngeo e vago são frequentemente associadas com enfermidade das bolsas guturais. A ocorrência desta lesão secundária a compressão pelo músculo estilofaríngeo não é reportada. Relata-se o caso de uma égua quarto de milha, 8 anos de idade, 450 kg, apresentando dispneia, ruído respiratório e perda de peso. No exame clínico observou-se dispnéia mista, taquicardia, disfagia, sialorréia, crepitação pulmonar e linfadenopatia submandibular e parotídea. Ao exame endoscópico identificou-se condrite aritenóide direita, colapso nasofaríngeo, edema generalizado da laringe e deslocamento dorsal do palato mole. Na avaliação da bolsa gutural direita identificou-se aumento de volume na origem do músculo estilofaríngeo com consequente compressão dos nervos cranianos XII, X e IX. Foi realizada traqueotomia, tratamento sistêmico com corticosteróides e antibióticos. Nenhuma resolução foi observada, após 16 dias o animal apresentou piora clínica, pleuropneumonia, uveíte, sepse grave, insuficiência renal aguda e foi submetido à eutanásia. A neuropatia mista resultou em rápida deterioração clínica do animal, devido à dificuldade de deglutição e processos respiratórios associados. Salienta-se a importância de se avaliar a origem do músculo estilofaríngeo em casos de colapso nasofaríngeo associado a disfagia em cavalos, dada a possibilidade de que alterações estruturais nesse músculo possam resultar em neuropatia laríngea.(AU)


Assuntos
Animais , Transtornos de Deglutição/diagnóstico , Doenças Nasofaríngeas/veterinária , Cavalos/anormalidades , Dispneia
2.
Braz. j. vet. res. anim. sci ; 56(1): e146549, jun. 2019. ilus
Artigo em Inglês | VETINDEX | ID: vti-22073

Resumo

Neuropathies of pharyngeal branches of glossopharyngeal and vagus are often associated with guttural pouches diseases; however, these branches of injury due to stylopharyngeus muscle compression are not reported. A case was reported of a quarter horse mare, 8 years old, 450 kg, presenting dyspnea and respiratory noise associated with weight loss. Clinical examination observed mixed dyspnea, tachycardia, dysphagia, sialorrhea, lung crackles and submandibular and parotid lymphadenopathy. Endoscopic exam showed right arytenoid chondritis, nasopharyngeal collapse, generalized larynx edema and dorsal displacement of the soft palate. Right guttural pouch evaluation showed swelling in the origin of stylopharyngeus muscle with consequent compression of the XII, X and IX cranial nerves. Tracheotomy, systemic treatment with corticosteroids, beta lactams and aminoglycosides antibiotics were performed. No resolution was observed and, after 16 days, the animal showed clinical worsening, developed pleuropneumonia, uveitis, severe sepsis, acute renal failure and was euthanized. The mixed neuropathy resulted in rapid clinical deterioration of the animal, due to the difficulty in swallowing and consequent associated respiratory processes. This report emphasizes the importance of evaluating stylopharyngeus muscle origin in cases of nasopharyngeal collapse associated with dysphagia in horses, given the possibility that structural changes in this muscle can result in laryngeal neuropathy.(AU)


As neuropatias do glossofaríngeo e vago são frequentemente associadas com enfermidade das bolsas guturais. A ocorrência desta lesão secundária a compressão pelo músculo estilofaríngeo não é reportada. Relata-se o caso de uma égua quarto de milha, 8 anos de idade, 450 kg, apresentando dispneia, ruído respiratório e perda de peso. No exame clínico observou-se dispnéia mista, taquicardia, disfagia, sialorréia, crepitação pulmonar e linfadenopatia submandibular e parotídea. Ao exame endoscópico identificou-se condrite aritenóide direita, colapso nasofaríngeo, edema generalizado da laringe e deslocamento dorsal do palato mole. Na avaliação da bolsa gutural direita identificou-se aumento de volume na origem do músculo estilofaríngeo com consequente compressão dos nervos cranianos XII, X e IX. Foi realizada traqueotomia, tratamento sistêmico com corticosteróides e antibióticos. Nenhuma resolução foi observada, após 16 dias o animal apresentou piora clínica, pleuropneumonia, uveíte, sepse grave, insuficiência renal aguda e foi submetido à eutanásia. A neuropatia mista resultou em rápida deterioração clínica do animal, devido à dificuldade de deglutição e processos respiratórios associados. Salienta-se a importância de se avaliar a origem do músculo estilofaríngeo em casos de colapso nasofaríngeo associado a disfagia em cavalos, dada a possibilidade de que alterações estruturais nesse músculo possam resultar em neuropatia laríngea.(AU)


Assuntos
Animais , Transtornos de Deglutição/diagnóstico , Doenças Nasofaríngeas/veterinária , Cavalos/anormalidades , Dispneia
3.
Arq. bras. med. vet. zootec. (Online) ; 70(6): 1691-1698, nov.-dez. 2018. graf, ilus
Artigo em Português | LILACS, VETINDEX | ID: biblio-969625

Resumo

A avaliação proteica do humor aquoso (HA) pode ser utilizada como método diagnóstico nas uveítes. Entretanto, estudos sobre as proteínas nesse fluido, em equinos hígidos, são escassos e apresentam variações conforme a metodologia empregada. Dessa forma, objetivou-se realizar a análise proteica e citológica do HA nessa espécie, bem como verificar sua correlação com as proteínas plasmáticas. Foram avaliados 13 equinos adultos (26 olhos), sem raça definida, machos ou fêmeas. Mediante aqueocentese, foi coletado 0,5 mL de humor aquoso de cada olho. Cada amostra foi encaminhada para quantificação proteica pelo método de Bradford modificado e pela eletroforese em gel de poliacrilamida - dodecil sulfato de sódio (SDS-PAGE), bem como para avaliação citológica. Por meio de venopunção, coletou-se sangue para determinação da concentração de proteínas séricas. Treze olhos (50% das amostras) apresentaram valor proteico médio de 40,3 mg/dL±6,45 e a eletroforese demonstrou presença de proteínas de massas mais elevadas que 43 KDa. Houve ausência de células em 96,15% das amostras (25 olhos). Equinos hígidos apresentaram baixa concentração de proteínas no HA. Já a correlação entre proteína no humor aquoso/proteína plasmática total foi de 0,56%.(AU)


Evaluation of equine aqueous humor (AH) proteins can help the diagnosis of uveitis. However, studies on proteins in this fluid in healthy horses are scarce and present variations according to the methodology employed. This study aimed to perform protein analysis and cytology of equine aqueous humor of healthy horses and verify its correlation with plasmatic proteins. Thirteen adult horses (26 eyes), mixed breed, male or female were evaluated. A volume of 0.5 mL of aqueous humor was collected through aqueocentesis from both eyes. The samples were submitted to protein quantification by modified Bradford method and to sodium dodecyl sulphate - polyacrylamide gel electrophoresis (SDS-PAGE), and to cytological evaluation. Blood was collected for determination of plasmatic protein concentration. Thirteen eyes (50% of the samples) had values larger than zero by the Bradford method, with an average of 40.3 mg/dl±6.45. Electrophoresis showed presence of higher masses of proteins (43 KDa). There were no cells in 96.15% of the samples (25 eyes). Healthy equines presented low protein concentration in the HA. The ratio between protein concentration in the aqueous humor / total plasma protein of 0.56%.(AU)


Assuntos
Animais , Humor Aquoso , Ligação Proteica , Cavalos/genética , Biologia Celular
4.
Arq. bras. med. vet. zootec. (Online) ; 70(6): 1691-1698, nov.-dez. 2018. graf, ilus
Artigo em Português | VETINDEX | ID: vti-21401

Resumo

A avaliação proteica do humor aquoso (HA) pode ser utilizada como método diagnóstico nas uveítes. Entretanto, estudos sobre as proteínas nesse fluido, em equinos hígidos, são escassos e apresentam variações conforme a metodologia empregada. Dessa forma, objetivou-se realizar a análise proteica e citológica do HA nessa espécie, bem como verificar sua correlação com as proteínas plasmáticas. Foram avaliados 13 equinos adultos (26 olhos), sem raça definida, machos ou fêmeas. Mediante aqueocentese, foi coletado 0,5 mL de humor aquoso de cada olho. Cada amostra foi encaminhada para quantificação proteica pelo método de Bradford modificado e pela eletroforese em gel de poliacrilamida - dodecil sulfato de sódio (SDS-PAGE), bem como para avaliação citológica. Por meio de venopunção, coletou-se sangue para determinação da concentração de proteínas séricas. Treze olhos (50% das amostras) apresentaram valor proteico médio de 40,3 mg/dL±6,45 e a eletroforese demonstrou presença de proteínas de massas mais elevadas que 43 KDa. Houve ausência de células em 96,15% das amostras (25 olhos). Equinos hígidos apresentaram baixa concentração de proteínas no HA. Já a correlação entre proteína no humor aquoso/proteína plasmática total foi de 0,56%.(AU)


Evaluation of equine aqueous humor (AH) proteins can help the diagnosis of uveitis. However, studies on proteins in this fluid in healthy horses are scarce and present variations according to the methodology employed. This study aimed to perform protein analysis and cytology of equine aqueous humor of healthy horses and verify its correlation with plasmatic proteins. Thirteen adult horses (26 eyes), mixed breed, male or female were evaluated. A volume of 0.5 mL of aqueous humor was collected through aqueocentesis from both eyes. The samples were submitted to protein quantification by modified Bradford method and to sodium dodecyl sulphate - polyacrylamide gel electrophoresis (SDS-PAGE), and to cytological evaluation. Blood was collected for determination of plasmatic protein concentration. Thirteen eyes (50% of the samples) had values larger than zero by the Bradford method, with an average of 40.3 mg/dl±6.45. Electrophoresis showed presence of higher masses of proteins (43 KDa). There were no cells in 96.15% of the samples (25 eyes). Healthy equines presented low protein concentration in the HA. The ratio between protein concentration in the aqueous humor / total plasma protein of 0.56%.(AU)


Assuntos
Animais , Humor Aquoso , Ligação Proteica , Cavalos/genética , Biologia Celular
5.
Acta sci. vet. (Impr.) ; 41: 01-05, 2013.
Artigo em Português | LILACS-Express | VETINDEX | ID: biblio-1457073

Resumo

Background: The equine eyelids and cilia protect the eye and promote normal ocular physiological function. Disorders in these structures may result in corneal alterations such as ulcers and stromal abscess. An abscess is a focal mixture of cellular debris, necrotic tissue, leucocytes and possibly infectious agents that initially create a lesion surrounded by a zone of reactive infl ammation. Ulcers and corneal stromal abscess cause severe ocular pain and loss of vision quality in horses. Medical and surgical treatments for stromal abscess have been developed and have evolved over many years. The aim of this work is to report a case of stromal abscess in a horse, after a corneal ulcer related to eyelid defi ciency, focusing on therapeutic methods.Case: A 10-year-old crossbreed mare was referred to the Veterinary Clinics Hospital (HCV) of UFPel with an ophthalmic disorder. The mare had an eyelid lesion 2 years before, and since this event she had had recurrent episodes of ophthalmologic disorders. On attendance at the HCV, the mare had photophobia, blepharospasm, conjunctival hyperemia, neovascularization, myosis, uveitis, intense ocular pain, eyelid defi ciency and a corneal ulcer about 2 cm long x 2 cm wide in the right eye. Surgical correction of eyelid and corneal disorder was recommended, but not authorized by the owner. Treatment was based on cleaning with physiological sol


Background: The equine eyelids and cilia protect the eye and promote normal ocular physiological function. Disorders in these structures may result in corneal alterations such as ulcers and stromal abscess. An abscess is a focal mixture of cellular debris, necrotic tissue, leucocytes and possibly infectious agents that initially create a lesion surrounded by a zone of reactive infl ammation. Ulcers and corneal stromal abscess cause severe ocular pain and loss of vision quality in horses. Medical and surgical treatments for stromal abscess have been developed and have evolved over many years. The aim of this work is to report a case of stromal abscess in a horse, after a corneal ulcer related to eyelid defi ciency, focusing on therapeutic methods.Case: A 10-year-old crossbreed mare was referred to the Veterinary Clinics Hospital (HCV) of UFPel with an ophthalmic disorder. The mare had an eyelid lesion 2 years before, and since this event she had had recurrent episodes of ophthalmologic disorders. On attendance at the HCV, the mare had photophobia, blepharospasm, conjunctival hyperemia, neovascularization, myosis, uveitis, intense ocular pain, eyelid defi ciency and a corneal ulcer about 2 cm long x 2 cm wide in the right eye. Surgical correction of eyelid and corneal disorder was recommended, but not authorized by the owner. Treatment was based on cleaning with physiological sol

6.
Acta sci. vet. (Impr.) ; 41(supl.1): Pub. 26, 2013. ilus
Artigo em Português | VETINDEX | ID: biblio-1372646

Resumo

Background: The equine eyelids and cilia protect the eye and promote normal ocular physiological function. Disorders in these structures may result in corneal alterations such as ulcers and stromal abscess. An abscess is a focal mixture of cellular debris, necrotic tissue, leucocytes and possibly infectious agents that initially create a lesion surrounded by a zone of reactive infl ammation. Ulcers and corneal stromal abscess cause severe ocular pain and loss of vision quality in horses. Medical and surgical treatments for stromal abscess have been developed and have evolved over many years. The aim of this work is to report a case of stromal abscess in a horse, after a corneal ulcer related to eyelid deficiency, focusing on therapeutic methods. Case: A 10-year-old crossbreed mare was referred to the Veterinary Clinics Hospital (HCV) of UFPel with an ophthalmic disorder. The mare had an eyelid lesion 2 years before, and since this event she had had recurrent episodes of ophthalmologic disorders. On attendance at the HCV, the mare had photophobia, blepharospasm, conjunctival hyperemia, neovascularization, myosis, uveitis, intense ocular pain, eyelid deficiency and a corneal ulcer about 2 cm long x 2 cm wide in the right eye. Surgical correction of eyelid and corneal disorder was recommended, but not authorized by the owner. Treatment was based on cleaning with physiological solution, gentamicin eyewash, autologus serum every 4 h, atropine 1% every 12 h topically, flunixin meglumin every 12 h intravenously. After 7 days, the corneal ulcer shrank, although there was no improvement in blepharospasm and ocular pain. A corneal abscess 3 cm x 2 cm was noticed. Gentamicin eyewash and autologus serum were administered topically every 4 h for 10 more days. After 14 days of treatment, there was neither blepharospasm nor corneal ulcer and the abscess was shrinking. Gentamicin eyewash was maintained every 6h for 3 more days. After 65 days there was minimal scar tissue in the eye. Discussion: The mare had an ocular traumatic injury 2 years ago and since this event she had presented uveitis and corneal ulcer recurrently, due to loss of eyelid and cilia functional integrity. Equine cornea is avascularized and vascularization of the affected lesion is necessary for resolution and abscess healing. Medical treatment of superfi cial stromal abscess is more economical than surgery and can result in good visual outcomes with mild scarring. Medical treatment consists of a combination of antimicrobial, mydriatic/cycloplegic and anti-inflammatory medications. Flunixin meglumin seems to be the most effective intravenous anti-inflammatory for controlling uveitis in horses. The anti-inflammatory dose may be reduced when there is a decrease in the anterior segment signs of infl ammation and ocular pain. Besides systemic colateral effects, anti-inflammatory therapy also reduces corneal vascularization, and therefore should be used carefully. Antibiotic topical therapy is highly recommended, due to ocular microflora and microorganism encapsulation, and it was used in the present report until there was full epithelial healing. A mydriatic/cycloplegic (atropine 1%) drug was administered aiming to dilate the pupil in order to prevent adherences and to reduce ocular discomfort. Antiproteases agents (autologus serum) are recommended when there is a corneal epithelial loss of integrity. This agent reduces collagen degradation and helps corneal healing. Stromal abscess in horses is usually associated with previous corneal ulceration, and in the present report it also involved eyelid functional deficiency. Medical treatment was effective, ensuring quality of future vision for the animal.


Assuntos
Animais , Feminino , Úlcera da Córnea/veterinária , Substância Própria , Abscesso/veterinária , Pálpebras/patologia , Doenças dos Cavalos/tratamento farmacológico
7.
Tese em Português | VETTESES | ID: vtt-206029

Resumo

Foram realizados estudos epidemiológicos da leptospirose equina na região sul do Rio Grande do Sul, a qual é uma zoonose tropical negligenciada causada por bactérias patogênicas do gênero Leptospira. Primeiramente, é apresentado um estudo sorológico transversal da leptospirose em equinos de tração usados por famílias com vulnerabilidade social para a coleta de materiais recicláveis. Como resultados, 89,9% (n=107) foram reagentes para um ou mais sorovares no Teste de Soroaglutinação Microscópica (MAT) com títulos iguais ou acima de 100. Hardjo (Hardjoprajitno) foi o sorovar mais prevalente no estudo. Fatores de exposição foram avaliados através de análise univariada, revelando associação de risco entre equinos pastarem em campo nativo e a sororeatividade no MAT (p=0,02) e a ocorrência de aborto (p<0,001). Além disso, a associação de risco entre monta natural (p<0,001), presença de roedores (p<0,001) e armazenamento de ração em galpão (p=0,03) e a ocorrência de aborto foi significativa. Posteriormente, é descrito o primeiro relato de uveíte recorrente equina (ERU) causada por leptospiras em equinos da raça crioula no Brasil, baseado nas manifestações clínicas, no diagnóstico laboratorial e na investigação epidemiológica. É descrito também um caso de aborto por leptospirose em uma égua no município de Pelotas (RS), onde foi possível isolar o agente, caracterizar a virulência em modelo animal e a caracterização genotípica preliminar da cepa isolada.Estes resultados sugerem que através desse estudo transversalfoi possível conhecer a prevalência de leptospiras, isolar o agente de cavalos usado em tração e diagnosticar uma uveíte recorrente equina em cavalos da raça crioula.


Epidemiological studies of equine leptospirosis were carried out in the southern region of Rio Grande do Sul, which is a neglected tropical zoonosis caused by pathogenic bacteria of Leptospira genus. Firstly, a cross-sectional serological study of leptospirosis in cart horses used by families with social vulnerability for recyclable materials collection is presented. As results, 89.9% (n=107) were reagents for one or more serovars in MAT with titers equal or above 100. Hardjo (Hardjoprajitno) was the most prevalent serovar in this study. Exposure risk factors were assessed by univariate analysis showed risk association between equines grazing on native grassland and seroreactivity in MAT (p=0.02) and abortion (p<0.001). In addition, the risk association between natural mating (p<0.001), presence of rodents near house (p<0.001), storage of feed in shed (p=0.03) and abortion was significant. Subsequently, the first report of equine recurrent uveitis (ERU) caused by leptospires in horses of the Crioula breed in Brazil is described, based on clinical manifestations, laboratory diagnosis and epidemiological investigation. It is also described a case of leptospirosis abortion in a mare in the municipality of Pelotas (RS), where it was possible to isolate the agent, characterize the virulence in animal model and the preliminary genotypic characterization of the isolated strain. These results suggest that through this cross-sectional study it was possible to know the prevalence of leptospires, to isolate the agent of horses used in traction and to diagnose equine recurrent uveitis in horses of the Crioula breed.

8.
Ci. Rural ; 42(7)2012.
Artigo em Português | VETINDEX | ID: vti-707848

Resumo

Environmental and behavioral factors make horses susceptible to corneal and conjunctival lesions, since these structures are constantly exposed to bacteria and fungi specially Aspergillus spp. and Fusarium spp. Bacterial and fungal ulcerative keratitis, as well as non-ulcerative fungal keratitis such as stromal abscess, are frequent in horses. A "cascade" effect follows the initial lesion which triggers the release of inflammatory cytokines followed by an acute and severe infiltrate of polymorphonuclear cells in the cornea. The cornea becomes susceptible to the activity of proteolytic enzymes released by microorganisms and polymorphonuclear cells, resulting in stromal degradation and ocular perforation. The medical treatment targeting the corneal disease and the controlling of reflexive uveitis should be aggressive and surgical therapy should be associated in most of the cases. This paper reviews the pathophysiology of keratomycosis in horses and specific aspects of the treatment in this species.


O cavalo, dado o seu meio ambiente, está sujeito a afecções frequentes da córnea e da conjuntiva, tecidos oculares bastante expostos a bactérias e fungos, principalmente Aspergillus spp. e Fusarium spp. As ceratites ulcerativas bacterianas e fúngicas, bem como as ceratites fúngicas não ulcerativas, caracterizadas principalmente pelo abscesso estromal, são frequentes nessa espécie. Ocorrida a lesão inicial, perpetua-se um ciclo vicioso, com liberação de citocinas inflamatórias, que desencadeiam uma rápida e severa infiltração corneal por células polimorfonucleares. A córnea torna-se sujeita à destruição por enzimas proteolíticas liberadas pelos micro-organismos e por células inflamatórias, capazes de desencadear a dissolução estromal e a perfuração do bulbo ocular. O tratamento clínico para a resolução da doença corneal e o controle da uveíte reflexa deve ser agressivo e associado, muitas das vezes, à terapia cirúrgica. Este artigo discorre sobre a fisiopatologia e o tratamento da ceratomicose em equinos.

9.
Artigo em Português | LILACS-Express | VETINDEX | ID: biblio-1479050

Resumo

Environmental and behavioral factors make horses susceptible to corneal and conjunctival lesions, since these structures are constantly exposed to bacteria and fungi specially Aspergillus spp. and Fusarium spp. Bacterial and fungal ulcerative keratitis, as well as non-ulcerative fungal keratitis such as stromal abscess, are frequent in horses. A "cascade" effect follows the initial lesion which triggers the release of inflammatory cytokines followed by an acute and severe infiltrate of polymorphonuclear cells in the cornea. The cornea becomes susceptible to the activity of proteolytic enzymes released by microorganisms and polymorphonuclear cells, resulting in stromal degradation and ocular perforation. The medical treatment targeting the corneal disease and the controlling of reflexive uveitis should be aggressive and surgical therapy should be associated in most of the cases. This paper reviews the pathophysiology of keratomycosis in horses and specific aspects of the treatment in this species.


O cavalo, dado o seu meio ambiente, está sujeito a afecções frequentes da córnea e da conjuntiva, tecidos oculares bastante expostos a bactérias e fungos, principalmente Aspergillus spp. e Fusarium spp. As ceratites ulcerativas bacterianas e fúngicas, bem como as ceratites fúngicas não ulcerativas, caracterizadas principalmente pelo abscesso estromal, são frequentes nessa espécie. Ocorrida a lesão inicial, perpetua-se um ciclo vicioso, com liberação de citocinas inflamatórias, que desencadeiam uma rápida e severa infiltração corneal por células polimorfonucleares. A córnea torna-se sujeita à destruição por enzimas proteolíticas liberadas pelos micro-organismos e por células inflamatórias, capazes de desencadear a dissolução estromal e a perfuração do bulbo ocular. O tratamento clínico para a resolução da doença corneal e o controle da uveíte reflexa deve ser agressivo e associado, muitas das vezes, à terapia cirúrgica. Este artigo discorre sobre a fisiopatologia e o tratamento da ceratomicose em equinos.

10.
Pesqui. vet. bras ; 31(2): 147-150, Feb. 2011. tab
Artigo em Inglês | VETINDEX | ID: vti-1017

Resumo

The objective of the study was to determine the association between clinical ophthalmic alterations and seroreactivity to leptospirosis by serovar Icterohaemorrhagiae in horses in Rio de Janeiro, Brazil. A total of 199 horses were studied. A microscopic agglutination test (MAT) was used to detect specific anti-Leptospira antibodies in blood serum. A total of 107 (53.8 percent) horses were seroreactive (titres > 200); 54 had high (> 800) titres, of which 44 were against serovar Icterohaemorrhagiae. Forty-two out of these 44, plus 40 seronegative horses (titers < 100) were given detailed ophthalmic examinations. Epiphora, ocular congestion, blepharospasm, photophobia, and peripapillary focal depigmentation were the most frequent alterations in seroreactive horses. Most ocular alterations were significantly more frequent in seroreactive horses. Horses seroreactive for leptospirosis (serovar Icterohaemorrhagiae) had a significantly higher prevalence of ophthalmic alterations than seronegative horses, providing additional evidence for an association between leptospirosis and equine uveitis.(AU)


O objetivo do estudo foi determinar a associação entre as alterações clínicas oftalmológicas e sororeatividade a leptospirose por serovar Icterohaemorrhagiae em cavalos no Rio de Janeiro. Um total de 199 animais foi estudado. O Teste da Aglutinação Microscópica foi utilizado para detectar anticorpos específicos anti-Leptospira no soro dos animais. Um total de 107 (53,8 por cento) dos cavalos foram sororeativos (títulos >200); 54 tinham títulos elevados (>800), dos quais 44 foram reativos contra o serovar Icterohaemorrhagiae. Quarenta e dois dentre estes 44, mais 40 cavalos soronegativos (títulos <100) foram submetidos ao exame oftalmológico. Epífora, congestão ocular, blefarospasmo, fotofobia, e despigmentação focal peripapilar foram as alterações mais frequentes nos animais sororeativos. Muitas alterações oculares foram significativamente mais frequentes em cavalos sororeativos. Animais sororeativos para leptospirose (serovar Icterohaemorrhagiae) tinham uma prevalência significativamente elevada de alterações oftálmicas em relação aos animais soronegativos, fornecendo evidências adicionais para associação entre leptospirose e uveíte equina.(AU)


Assuntos
Animais , Cavalos , Leptospira interrogans serovar icterohaemorrhagiae , Técnicas de Diagnóstico Oftalmológico/veterinária
11.
Ci. Rural ; 38(9)2008.
Artigo em Português | VETINDEX | ID: vti-705708

Resumo

The clinical records of 805 horses admitted to the Veterinary Hospital of the State University of Londrina between 1992 and 2007 were reviewed in order to establish the occurrence of ophthalmologic diseases in horses used for hauling carts in Londrina, Paraná, Brazil. Among these records, there were 25 ophthalmologic cases (3.1%), composed of 12 cases (48%) of corneal diseases, six cases (24%) of cataracts, six cases (24%) of conjunctival diseases (associated or not to other lesions), two cases (8%) of recurrent equine uveitis, one case of squamous cell carcinoma of the third eyelid, one case of chronic necrotic eyelid lesion with loss of the eye globe and one case of phthisis bulbi (4% each). Trauma was the most important etiology for eye diseases diagnosed in this study (36%). Most of the ophthalmologic diseases seen in this study may cause blindness if not adequately treated, and this might prevent the animal from performing draught activities. Therefore, this study helps to emphasize the need of continuously making cart owners aware of the importance and prevention of such conditions.


Com o objetivo de verificar a ocorrência de doenças oculares em eqüinos utilizados para serviços de tração urbana na cidade de Londrina, PR, foram revistos os registros clínicos de 805 eqüinos atendidos no Hospital Veterinário da Universidade Estadual de Londrina no período entre 1992 e 2007. Nesses registros clínicos foram verificados 25 casos de doenças oftalmológicas (3,1%), compostas por 12 casos (48%) de doenças da córnea, seis casos (24%) de catarata, seis casos (24%) de doenças da conjuntiva (paralelas a outras enfermidades oculares ou não), dois casos (8%) de uveíte recorrente eqüina, um caso de carcinoma de células escamosas da terceira pálpebra, um caso de lesão crônica de pálpebra, com necrose e perda do globo ocular, e um caso de Phthisis bulbi (4% cada). A principal causa das enfermidades oftalmológicas diagnosticadas nesses animais foi traumática (36% dos casos). A maioria das doenças diagnosticadas neste estudo, se não tratadas adequadamente, pode resultar em cegueira e, conseqüentemente, pode inutilizar o animal para uso em tração urbana. Isso reforça a necessidade de conscientização dos carroceiros sobre a importância e a profilaxia dessas enfermidades.

12.
Ci. Rural ; 38(9)2008.
Artigo em Português | VETINDEX | ID: vti-705666

Resumo

The clinical records of 805 horses admitted to the Veterinary Hospital of the State University of Londrina between 1992 and 2007 were reviewed in order to establish the occurrence of ophthalmologic diseases in horses used for hauling carts in Londrina, Paraná, Brazil. Among these records, there were 25 ophthalmologic cases (3.1%), composed of 12 cases (48%) of corneal diseases, six cases (24%) of cataracts, six cases (24%) of conjunctival diseases (associated or not to other lesions), two cases (8%) of recurrent equine uveitis, one case of squamous cell carcinoma of the third eyelid, one case of chronic necrotic eyelid lesion with loss of the eye globe and one case of phthisis bulbi (4% each). Trauma was the most important etiology for eye diseases diagnosed in this study (36%). Most of the ophthalmologic diseases seen in this study may cause blindness if not adequately treated, and this might prevent the animal from performing draught activities. Therefore, this study helps to emphasize the need of continuously making cart owners aware of the importance and prevention of such conditions.


Com o objetivo de verificar a ocorrência de doenças oculares em eqüinos utilizados para serviços de tração urbana na cidade de Londrina, PR, foram revistos os registros clínicos de 805 eqüinos atendidos no Hospital Veterinário da Universidade Estadual de Londrina no período entre 1992 e 2007. Nesses registros clínicos foram verificados 25 casos de doenças oftalmológicas (3,1%), compostas por 12 casos (48%) de doenças da córnea, seis casos (24%) de catarata, seis casos (24%) de doenças da conjuntiva (paralelas a outras enfermidades oculares ou não), dois casos (8%) de uveíte recorrente eqüina, um caso de carcinoma de células escamosas da terceira pálpebra, um caso de lesão crônica de pálpebra, com necrose e perda do globo ocular, e um caso de Phthisis bulbi (4% cada). A principal causa das enfermidades oftalmológicas diagnosticadas nesses animais foi traumática (36% dos casos). A maioria das doenças diagnosticadas neste estudo, se não tratadas adequadamente, pode resultar em cegueira e, conseqüentemente, pode inutilizar o animal para uso em tração urbana. Isso reforça a necessidade de conscientização dos carroceiros sobre a importância e a profilaxia dessas enfermidades.

13.
Artigo em Português | LILACS-Express | VETINDEX | ID: biblio-1477418

Resumo

The clinical records of 805 horses admitted to the Veterinary Hospital of the State University of Londrina between 1992 and 2007 were reviewed in order to establish the occurrence of ophthalmologic diseases in horses used for hauling carts in Londrina, Paraná, Brazil. Among these records, there were 25 ophthalmologic cases (3.1%), composed of 12 cases (48%) of corneal diseases, six cases (24%) of cataracts, six cases (24%) of conjunctival diseases (associated or not to other lesions), two cases (8%) of recurrent equine uveitis, one case of squamous cell carcinoma of the third eyelid, one case of chronic necrotic eyelid lesion with loss of the eye globe and one case of phthisis bulbi (4% each). Trauma was the most important etiology for eye diseases diagnosed in this study (36%). Most of the ophthalmologic diseases seen in this study may cause blindness if not adequately treated, and this might prevent the animal from performing draught activities. Therefore, this study helps to emphasize the need of continuously making cart owners aware of the importance and prevention of such conditions.


Com o objetivo de verificar a ocorrência de doenças oculares em eqüinos utilizados para serviços de tração urbana na cidade de Londrina, PR, foram revistos os registros clínicos de 805 eqüinos atendidos no Hospital Veterinário da Universidade Estadual de Londrina no período entre 1992 e 2007. Nesses registros clínicos foram verificados 25 casos de doenças oftalmológicas (3,1%), compostas por 12 casos (48%) de doenças da córnea, seis casos (24%) de catarata, seis casos (24%) de doenças da conjuntiva (paralelas a outras enfermidades oculares ou não), dois casos (8%) de uveíte recorrente eqüina, um caso de carcinoma de células escamosas da terceira pálpebra, um caso de lesão crônica de pálpebra, com necrose e perda do globo ocular, e um caso de Phthisis bulbi (4% cada). A principal causa das enfermidades oftalmológicas diagnosticadas nesses animais foi traumática (36% dos casos). A maioria das doenças diagnosticadas neste estudo, se não tratadas adequadamente, pode resultar em cegueira e, conseqüentemente, pode inutilizar o animal para uso em tração urbana. Isso reforça a necessidade de conscientização dos carroceiros sobre a importância e a profilaxia dessas enfermidades.

14.
Artigo em Inglês | VETINDEX | ID: vti-442980

Resumo

Equine leptospirosis can present a non-symptomatic form, an acute clinical form, or even develop chronically, causing reproductive alterations, such as abortion and recurrent uveitis. Since the prevalence of leptospirosis in several countries and regions is widely reported, the objective of this study was to verify the prevailing equine leptospirosis in different regions of Brazil. Sera from 1402 blood samples from horses of different age, sex, breed, and purpose were examined. These samples came from southeastern and central west states of Brazil. The method utilized was the Microscopic Agglutination Test (MAT), with 12 different Leptospira serovars. From the sera tested, 754 (54%) were positive for one (385) or more (372) serovars. These results were higher when compared to national and international levels. The most commonly found serovars were icterohaemorrhagiae (37.01%), suggesting exposure to rodents, castellonis (16.97%), and djasiman (15.19%). There were significant differences of reagents between sexes, and a tendency toward higher positivity with age. Distribution of sera-reagents related to aptitude showed a markedly higher value for work animals than for sporting ones. Higher rates were found for animals with undefined breed. There were no significant differences related to regional origin. As an indication of multiple exposure, significant associations were observed between the following serovars: castellonis and djasiman; castellonis and grippotyphosa; castellonis and copenhageni; castellonis and icterohaemorrhagiae; castellonis and pomona; canicola and pomona; canicola and djasiman; djasiman and copenhageni; icterohaemorrhagiae and djasiman; icterohaemorrhagiae and pyrogenes; copenhageni and pomona. These results showed the necessity of further studies on the epidemiology of this disease in equines and its relationship to human illness.

15.
Jaboticabal; s.n; 07/05/2009. 64 p.
Tese em Português | VETTESES | ID: vtt-4593

Resumo

A doença endógena inflamatória uveal em equinos constitui resposta imunopatogênica complexa, onde se admite a participação de uma variedade de antígenos. A uveíte recorrente dos equinos (URE), também denominada ophthalmia periódica ou moon blindness, é uma panuveíte e constitui-se na causa mais comum de diminuição da percepção visual, cuja patogênese permanece, ainda, sob investigação. Inúmeras pesquisas apontam para a hipótese de hipersensibilidade a antígenos bacterianos. A maioria dos estudos mostra evidências de infecção por Leptospira sp.. Examinaram-se, ao acaso, os olhos de 29 animais e coletaram-se o soro, o humor aquoso e o corpo vítreo para proteinograma e aglutinação microscópica para Leptospira sp.. Outrossim, fragmentos de córnea, íris, retina e coróide para histopatologia e imunoistoquímica. A prova de aglutinação microscópica identificou 14 animais positivos, seis animais com titulação igual a 40 e nove indivíduos negativos para as amostras de soro. Houve um animal positivo na amostra de humor aquoso e na de corpo vítreo e outro negativo na de soro (titulação 40), mas positivo na de corpo vítreo. Foram encontrados os sorovares icterohaemorrhagiae, autumalis, patoc, sentot, habdomadis. Foram identificadas, à eletroforese do soro, as proteínas: imunoglobulina A; ceruloplasmina; trasnferrina; hemopexina; albumina; anti-tripsina; imunoglobulina G de cadeia pesada; haptoglobina; glicoproteína ácida; imunoglobulina G de cadeia leve e proteína de 25kda. A única proteína que mostrou resultado estatístico significativo foi a ceruplasmina (p=0,05) com animais soropositivos para leptospirose. À histopatologia a espessura da córnea foi significativamente maior nos animais soropositivos (p=0,0347). O exame imunistoquímico para pesquisa da bactéria Leptospira sp. mostrou maior...


Endogenous uveal inflammatory disease in the horse represent a complex immunopathological response to a range of presumed antigens. Equine recurrent uveitis (ERU) is a panuveitis and the most commmon cause of blindness in horses. Many researchers favour the hypothesis that ERU is delayed type hypersensitivity response to bacterial antigens. New findings show evidence of leptospiral infection in ERU eyes. Fifity eight eyeballs from twenty nine horses randomly selected were studied using histopathology and immunohistochemistry. The serum from 29 animals, aqueous humor an vitreous body from 58 eyes were collected for proteinogram and microscopic agglutination test (MAT) for Leptospira sp.. The microscopic agluttination test was identified 14 positive animals, six with titer 40 and nine negative in serum samples. One seropositive animal was positive in aquaeous humor and vitreous body and another seronegative horse was positive in vitreous body. Were found five serovars from 26 studied from Leptospira interrogans: icterohaemorrhagiae, autumalis, patoc, sentot, habdomadis. Were identified by serum electrophoresis, the following proteins: immunoglobulin A; ceruloplasmin; trasnferrina; hemopexina; albumin, anti-trypsin, the heavy chain of immunoglobulin G; haptoglobin; glycoprotein, immunoglobulin G and the light chain protein, 25kda. The only protein that showed significant results with seropositive horses was ceruplasmin (p = 0.05). The pathomorphologic changes on HE-stained sections showed that seropositive animals for leptospirosis had corneal thickness significantly higher than the seronegative (p = 0.0347). The immunohistochemistry test for Leptospira sp. showed higher positivity in samples of cornea, and some animals were seronegative but positive for this test. At immunohistochemistry was observed that the anti-metalloproteinase...

16.
Ci. Rural ; 30(2)2000.
Artigo em Português | VETINDEX | ID: vti-703627

Resumo

Known as the leading cause of blindness in horses, equine recurrent uveitis (ERU) is characterized by several attacks of intra-ocular inflammation alternated with variable periods of clinical quiescence. Although many factors have been related to ERU it seems that Leptospira interrogans and the microfilaria of Onchocerca cervicalis play an important role in the pathogenesis through an immune-mediated mechanism. Clinical findings in the acute phase include variable degrees of epifora, blepharospasm, photophobia, conjunctival hyperemia, miosis, corneal opacity, aqueous flare, hyphema, and hypopyon. Clinical findings consistent with chronic phase include synechiae, changes in shape and pigmentation of the lens, cataract and lens luxation or subluxation. The principal goals of treatment are reduction of uveal inflammation, preservation of pupil's motility, and prevention of blindness. Therapy consists mainly of antiinflamatory and mydriatics/cycloplegic drugs. The prognosis for preservation of vision varies with severity and frequency of recurrencies, and the success of the treatment.


Conhecida como uma das mais importantes causas de cegueira nos eqüinos, a uveíte recorrente eqüina (URE) caracteriza-se por repetidos episódios de inflamação ocular interrompidos por períodos variáveis de quiescência clínica. Muito embora diversos fatores tenham sido relacionados à ocorrência de URE, acredita-se que a doença se desenvolva pela ação de agentes como Leptospira interrogans e a microfilária do nematóide Onchocerca cervicalis, em conseqüência de reações imunomediadas intra-oculares. Os sinais clínicos da fase aguda, como epífora, blefarospasmo, fotofobia, hiperemia conjuntival, miose, opacidade corneana e do humor aquoso, hifema e hipópio, podem ser encontrados em diferentes graus. Os sinais da fase crônica podem incluir sinéquias, alterações na forma e pigmentação normais da íris, luxação ou subluxação do cristalino e catarata, entre outros. O tratamento tem como principais objetivos a redução da inflamação uveal, a preservação da motilidade da pupila e a prevenção de seqüelas que levem à cegueira, e consiste, fundamentalmente, no uso de drogas antiinflamatórias e midriáticos e cicloplégicos. O prognóstico, quanto à conservação da visão, está na dependência da intensidade e freqüência dos episódios recorrentes e do sucesso do tratamento.

17.
Artigo em Português | LILACS-Express | VETINDEX | ID: biblio-1475383

Resumo

Known as the leading cause of blindness in horses, equine recurrent uveitis (ERU) is characterized by several attacks of intra-ocular inflammation alternated with variable periods of clinical quiescence. Although many factors have been related to ERU it seems that Leptospira interrogans and the microfilaria of Onchocerca cervicalis play an important role in the pathogenesis through an immune-mediated mechanism. Clinical findings in the acute phase include variable degrees of epifora, blepharospasm, photophobia, conjunctival hyperemia, miosis, corneal opacity, aqueous flare, hyphema, and hypopyon. Clinical findings consistent with chronic phase include synechiae, changes in shape and pigmentation of the lens, cataract and lens luxation or subluxation. The principal goals of treatment are reduction of uveal inflammation, preservation of pupil's motility, and prevention of blindness. Therapy consists mainly of antiinflamatory and mydriatics/cycloplegic drugs. The prognosis for preservation of vision varies with severity and frequency of recurrencies, and the success of the treatment.


Conhecida como uma das mais importantes causas de cegueira nos eqüinos, a uveíte recorrente eqüina (URE) caracteriza-se por repetidos episódios de inflamação ocular interrompidos por períodos variáveis de quiescência clínica. Muito embora diversos fatores tenham sido relacionados à ocorrência de URE, acredita-se que a doença se desenvolva pela ação de agentes como Leptospira interrogans e a microfilária do nematóide Onchocerca cervicalis, em conseqüência de reações imunomediadas intra-oculares. Os sinais clínicos da fase aguda, como epífora, blefarospasmo, fotofobia, hiperemia conjuntival, miose, opacidade corneana e do humor aquoso, hifema e hipópio, podem ser encontrados em diferentes graus. Os sinais da fase crônica podem incluir sinéquias, alterações na forma e pigmentação normais da íris, luxação ou subluxação do cristalino e catarata, entre outros. O tratamento tem como principais objetivos a redução da inflamação uveal, a preservação da motilidade da pupila e a prevenção de seqüelas que levem à cegueira, e consiste, fundamentalmente, no uso de drogas antiinflamatórias e midriáticos e cicloplégicos. O prognóstico, quanto à conservação da visão, está na dependência da intensidade e freqüência dos episódios recorrentes e do sucesso do tratamento.

18.
Acta sci. vet. (Online) ; 41: 01-05, 2013.
Artigo em Português | VETINDEX | ID: vti-475503

Resumo

Background: The equine eyelids and cilia protect the eye and promote normal ocular physiological function. Disorders in these structures may result in corneal alterations such as ulcers and stromal abscess. An abscess is a focal mixture of cellular debris, necrotic tissue, leucocytes and possibly infectious agents that initially create a lesion surrounded by a zone of reactive infl ammation. Ulcers and corneal stromal abscess cause severe ocular pain and loss of vision quality in horses. Medical and surgical treatments for stromal abscess have been developed and have evolved over many years. The aim of this work is to report a case of stromal abscess in a horse, after a corneal ulcer related to eyelid defi ciency, focusing on therapeutic methods.Case: A 10-year-old crossbreed mare was referred to the Veterinary Clinics Hospital (HCV) of UFPel with an ophthalmic disorder. The mare had an eyelid lesion 2 years before, and since this event she had had recurrent episodes of ophthalmologic disorders. On attendance at the HCV, the mare had photophobia, blepharospasm, conjunctival hyperemia, neovascularization, myosis, uveitis, intense ocular pain, eyelid defi ciency and a corneal ulcer about 2 cm long x 2 cm wide in the right eye. Surgical correction of eyelid and corneal disorder was recommended, but not authorized by the owner. Treatment was based on cleaning with physiological sol


Background: The equine eyelids and cilia protect the eye and promote normal ocular physiological function. Disorders in these structures may result in corneal alterations such as ulcers and stromal abscess. An abscess is a focal mixture of cellular debris, necrotic tissue, leucocytes and possibly infectious agents that initially create a lesion surrounded by a zone of reactive infl ammation. Ulcers and corneal stromal abscess cause severe ocular pain and loss of vision quality in horses. Medical and surgical treatments for stromal abscess have been developed and have evolved over many years. The aim of this work is to report a case of stromal abscess in a horse, after a corneal ulcer related to eyelid defi ciency, focusing on therapeutic methods.Case: A 10-year-old crossbreed mare was referred to the Veterinary Clinics Hospital (HCV) of UFPel with an ophthalmic disorder. The mare had an eyelid lesion 2 years before, and since this event she had had recurrent episodes of ophthalmologic disorders. On attendance at the HCV, the mare had photophobia, blepharospasm, conjunctival hyperemia, neovascularization, myosis, uveitis, intense ocular pain, eyelid defi ciency and a corneal ulcer about 2 cm long x 2 cm wide in the right eye. Surgical correction of eyelid and corneal disorder was recommended, but not authorized by the owner. Treatment was based on cleaning with physiological sol

19.
Artigo em Inglês | VETINDEX | ID: vti-743127

Resumo

Neuropathies of pharyngeal branches of glossopharyngeal and vagus are often associated with guttural pouches diseases; however, these branches of injury due to stylopharyngeus muscle compression are not reported. A case was reported of a quarter horse mare, 8 years old, 450 kg, presenting dyspnea and respiratory noise associated with weight loss. Clinical examination observed mixed dyspnea, tachycardia, dysphagia, sialorrhea, lung crackles and submandibular and parotid lymphadenopathy. Endoscopic exam showed right arytenoid chondritis, nasopharyngeal collapse, generalized larynx edema and dorsal displacement of the soft palate. Right guttural pouch evaluation showed swelling in the origin of stylopharyngeus muscle with consequent compression of the XII, X and IX cranial nerves. Tracheotomy, systemic treatment with corticosteroids, beta lactams and aminoglycosides antibiotics were performed. No resolution was observed and, after 16 days, the animal showed clinical worsening, developed pleuropneumonia, uveitis, severe sepsis, acute renal failure and was euthanized. The mixed neuropathy resulted in rapid clinical deterioration of the animal, due to the difficulty in swallowing and consequent associated respiratory processes. This report emphasizes the importance of evaluating stylopharyngeus muscle origin in cases of nasopharyngeal collapse associated with dysphagia in horses, giv


As neuropatias do glossofaríngeo e vago são frequentemente associadas com enfermidade das bolsas guturais. A ocorrência desta lesão secundária a compressão pelo músculo estilofaríngeo não é reportada. Relata-se o caso de uma égua quarto de milha, 8 anos de idade, 450 kg, apresentando dispneia, ruído respiratório e perda de peso. No exame clínico observou-se dispnéia mista, taquicardia, disfagia, sialorréia, crepitação pulmonar e linfadenopatia submandibular e parotídea. Ao exame endoscópico identificou-se condrite aritenóide direita, colapso nasofaríngeo, edema generalizado da laringe e deslocamento dorsal do palato mole. Na avaliação da bolsa gutural direita identificou-se aumento de volume na origem do músculo estilofaríngeo com consequente compressão dos nervos cranianos XII, X e IX. Foi realizada traqueotomia, tratamento sistêmico com corticosteróides e antibióticos. Nenhuma resolução foi observada, após 16 dias o animal apresentou piora clínica, pleuropneumonia, uveíte, sepse grave, insuficiência renal aguda e foi submetido à eutanásia. A neuropatia mista resultou em rápida deterioração clínica do animal, devido à dificuldade de deglutição e processos respiratórios associados. Salienta-se a importância de se avaliar a origem do músculo estilofaríngeo em casos de colapso nasofaríngeo associado a disfagia em cavalos, dada a possibilidade de que alterações estruturais nesse m

20.
Jaboticabal; s.n; 24/02/2006. 74 p.
Tese em Português | VETTESES | ID: vtt-8853

Resumo

A Uveíte Recorrente Eqüina (URE) tem a Leptospira spp como o patógeno mais freqüentemente implicado como agente etiológico, e diversos estudos relatam relação entre sororreatividade à leptospirose e uveítes. Para a obtenção de dados sobre esta etiologia e sua ocorrência, 50 eqüinos reagentes e 50 não reagentes a Leptospira spp foram submetidos a exame oftálmico clínico e pesquisa de anticorpos contra 19 sorovares de Leptospira interrogans em amostras de sangue e de humor aquoso, além de tentativa de isolamento do agente do humor aquoso. As amostras também foram submetidas à avaliação química e bioquímica, e os globos oculares a exame anatomopatológico. Nenhum eqüino apresentou sinais clínicos característicos de uveíte aguda, porém cinco do grupo reagente apresentaram lesões de fundo de olho compatíveis com uma coriorretinite focal, confirmadas pelo exame anatomopatológico. O soro e o humor aquoso da maioria dos animais apresentaram níveis diferentes dos considerados normais para os indicadores avaliados, mas não de forma semelhante entre os eqüinos, indicando não haver causa em comum, e as alterações séricas não se relacionaram às do humor aquoso de modo a indicar lesão de tecidos oculares


Leptospiral organisms have long been presumed to be associated with the occurence of Equine Recurrent Uveitis (ERU). To determine further data on this organism as possible cause, as well as of the occurrence of this disease in horses in Brazil, 100 horses were studied, being 50 positive and 50 negative for the presence of anti -Leptospira interrogans antibodies. The horses were ophthalmologically assessed, and the presence of specitic antibodies for 19 different sorovars in serum and aqueous humor was researched. These samples were also assessed as to levels of chemical and biochemical indicators, and ali eyes underwent pathological histology examination. An attempt was made to isolate leptospiral organisms from aqueous humor samples. None of the horses showed clinical signs indicating acute uveitis, although tive presented lesions and histological finds compatible with focal coriorretinitis. Levels of ali evaluated indicators in serum and aqueous humor were seen to vary from normal values in most of the animais, although the variations were not similar between the horses. This would indicate that these variations did not originate from the same cause. There was no indication of lesions in eye structures, since variation in indicator levels in sera did not relate variations of aqueous humor

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