Tumor ósseo multilobular em cão da raça yorkshire terrier: relato de caso / Multilobular bone tumor in yorkshire terrier breed dog: case report

O tumor ósseo multilobular, também conhecido como osteocondrossarcoma multilobular ou chondroma rodens, é um tumor maligno de crescimento lento, localmente invasivo, capaz de comprimir e invadir o tecido adjacente. Sua ocorrência é maior nos ossos planos do crânio e palato duro. Os sinais clínicos dependem da localização do tumor e, geralmente, estão relacionados à compressão de estruturas adjacentes. Neste relato, descreve-se um caso de tumor ósseo multilobular em uma cadela de 9 anos de idade, raça yorkshire terrier, com crescimento progressivo em região sobreposta à topografia de arco zigomático esquerdo e porção caudal do ramo mandibular esquerdo. Após realização de avaliação radiográfica de crânio, tomografia computadorizada e investigação laboratorial, foi realizada a remoção cirúrgica e exame histopatológico, que confirmaram a suspeita de tumor ósseo multilobular. Portanto, a avaliação histopatológica associada aos exames de imagem permitiu o estabelecimento do diagnóstico de tumor ósseo multilobular, uma neoplasia pouco descrita na clínica veterinária brasileira em cães de pequeno porte.(AU)

Multilobularbone tumor, also known as multilobular osteochondrosarcoma or chondroma rodens, it is a slow-growing, locally invasive, malignant tumor capable of compressing and invading adjacenttissue. Its occurrence is higher in the flat bones of the skull and hard palate. Clinical signs depend on the location of the tumor and are usually related to compression of adjacent structures. This report describes a case of multilobular bone tumor in a nine-year-old female yorkshire terrier breed, with progressive growth in a region overlapping the topography of the left zygomatic arch and the caudal portion of the left mandibular ramus. After performing a radiographic evaluation of the skull, computed tomography and laboratory investigation, surgical removal and histopathology were performed, which confirmed the suspicion of a multilobular bonetumor. Therefore, the histopathology associated with imaging exams allowed the establishment of a diagnosis of multilobular bonetumor, a neoplasm rarely described in the Brazilian veterinary clinic of small dogs.(AU)

Foramen magnum in dogs of small and toy breeds - morphometric study

Introduction: The foramen magnum is located in the occipital bone and communicates the cranial cavity with the spinal canal of the vertebral column. Variations in the shape and size of this foramen, such as the presence of a notch in its dorsal contour, characterize occipital dysplasia and may occur due to a defect in the supraoccipital bone ossification process during the gestational period. Occipital dysplasia has been reported primarily in small, toy, and brachycephalic breeds, and its clinical relevance remains controversial. The aim of the present study was to evaluate the size of the foramen magnum in asymptomatic dogs of small and toy breeds. Materials, Methods & Results: The study was conducted at the Veterinary Hospital of the Center for Rural Health and Technology of the Federal University of Campina Grande (UFCG), Patos Campus, located in Paraíba state, Brazil. Twelve (n = 12) asymptomatic, small and toy breed dogs, with variable sex and over 10 months of age, were referred to the Veterinary Hospital for elective surgical procedures and were used in this study. All dogs underwent complete neurological examination to confirm the asymptomatic status and were radiographed in rostrocaudal position, with their mouths closed and the hard palate at an angle of approximately 70º to 80º with the table of the X-ray apparatus. The foramen magnum of each specimen was evaluated in the radiographs using a precision caliper. The analyzed parameters included height (H), the height of the dorsal notch (N), total height (H+N), and width (W), and the obtained data were used to establish the degree of occipital dysplasia and determine the shape of the foramen magnum. Of the 12 animals studied, 75% (n = 9) exhibited a dorsal notch in the foramen magnum, which varied between 3.00 and 10.00 millimeters (mm) in height, characterizing occipital dysplasia. Among the affected animals, 77.77% (n = 7) were classified as grade 1 for the alteration, 11.11% (n = 1) as grade 2 and one animal (11.11%) as grade 3. The prevalent shape observed for the foramen magnum was oval (83.3%). Discussion: Although occipital dysplasia has been associated with the occurrence of nonspecific neurological clinical signs, such as tremors, ataxia, and epileptic seizures, the presence of this alteration in asymptomatic dogs indicates that the formation alone is just an anatomical variation, as demonstrated herein and in previous studies conducted over the past few years. This hypothesis has been increasingly supported by scientific evidence through publications that portray occipital dysplasia in dogs of various breeds and sizes without clinical manifestations. The clinical signs attributed to occipital dysplasia may originate in situations where there is a coexistence of other conditions. Occipital dysplasia has been reported several times in conjunction with other pathologies, such as occipital hypoplasia and syringomyelia, in symptomatic dogs. The dorsal notch-shaped occipital defect is covered by a fibrous tissue membrane in dogs affected by occipital dysplasia. The presence of this soft tissue membrane has been related to the late onset of syringomyelia due to the decompressive effect that it provides to the flow of cerebrospinal fluid. When occipital dysplasia is identified in symptomatic dogs, it is suggested that the lesion be correctly located within the nervous system and that, according to its neurolocalization, a thorough investigation of other underlying causes for the occurrence of the neurological clinical manifestation be carried out. To date, there is no evidence characterizing occipital dysplasia as a single entity causing neurological deficits.

Chemodectoma in a bitch

Background: Chemodectomas, better known as tumors of the base of the heart, arise from aortic bodies, respiratory chemoreceptors located near or inside the aortic arch or originate from receptors located in the carotid arteries. Relatively rare, they affect dogs and, to a lesser extent, cats. They gain great importance when they influence the function of the cardiovascular system, with animals showing clinical signs related to congestive heart failure. Clinical diagnosis is based on symptomatology and complementary tests such as radiography, electrocardiography and echocardiography, while the definitive diagnosis is obtained by cytological and histopathological exams. This study aims to reports a case of malignant chemodectoma in a bitch, whose main symptomatology was neurological and not cardiovascular. Case: A 1-year-old Rottweiler bitch was attended with neurological alterations compatible with vestibular syndrome, hyporexia, dysphagia, apathy, melena, emesis, and purulent nasal discharge on the right nostril. On physical examination, the animal showed depressed level of consciousness, poor body condition, bilateral quemosis, paralysis of the right eye, inspiratory dyspnea and muffling of cardiac auscultation, besides a subcutaneous nodule between the scapulae. On neurological evaluation, horizontal nystagmus, head tilt to the right side, ventromedial strabismus and facial nerve paralysis on the right side were observed so that the localization of the lesion was set in peripheral vestibular system. During anesthesia for esophageal tube placement, a mass from the hard palate to the oropharynx was noted, making endotracheal intubation impossible to perform. Biopsy of this nodule was performed, and tracheostomy was indicated, but the owner opted for euthanasia before the procedure. Necropsy revealed white soft masses in the bilateral retromandibular region, on the subcutaneous tissue near the scapulae, in the right ear and since nasopharynx to the soft palate, in addition to sparse white nodules in the heart, lung, carotid artery, kidneys, right ovary, mesentery near to the spleen, and axillary lymph node. Histologically, the nodules were characterized by neoplastic cells population organized in short bundles or cords, arranged around small blood vessels surrounded by delicate connective tissue. Neoplastic cells infiltrated muscles and blood and lymphatic vessels were filled by multiple neoplastic emboli. The histological pattern of the cells allowed the diagnosis of chemodectoma. Discussion: The bitch from this case had 1-year-old when diagnosed with chemodectoma, differently from most cases from literature, that are between 7 to 15 years old. Furthermore, primarily cardiac tumors are considered rare, being chemodectoma the most common, often reported in Boxer and Boston Terrier dogs, but unusual in Rottweilers. Despites some articles mentioning seizure and Horner's Syndrome secondary to a carotid body chemodectoma, neurological signs are not commonly observed in these cases. The presence of the tumor in the middle ear region of the right side supports the occurrence of peripheral vestibular syndrome and facial nerve paralysis on the same side. Because it is a neoplasm that is usually detected late during the course of the disorder, most patients either cannot obtain diagnosis in vivo, as in this reported animal, which was in such a critical condition that underwent euthanasia, or there are no more possible therapeutic choices. In the patient described, there were numerous metastatic masses and nodules spread throughout the body. Although the typical clinical signs in animals with chemodectomas are often related to heart disease, neurological signs may also be present. This report emphasizes the importance of chemodectoma being included as a differential diagnosis in young dogs and even in breeds such as Rottweiler.

Osteosarcoma of the hard palate in a dog - case report / [Osteossarcoma em palato duro de cão - relato de caso]

The osteosarcoma (OSA) is the most diagnosed primary bone cancer in canine patients. This work reports a case of a canine, six years old, mongrel, female, intact, with an OSA in the hard palate. Physical examination detected a firm mass in the palate. Thoracic radiographs, hematological and biochemical exams, histopathological exams and computed tomography were requested. A chondroblastic OSA was diagnosed and the tumor was characterized by immunohistochemistry. There was never evidence of metastasis in this case. The treatment consisted of the combination of conventional chemotherapy, metronomic chemotherapy, and palliative care, aiming at greater survival and well-being of the patient since surgical excision was not possible due to the location and extension of the tumor. Osteogenic sarcomas of the hard palate are rarely seen and described in the literature. In this article we present a characterization of the osteosarcoma with uncommon localization in the hard palate.(AU)

O osteossarcoma (OSA) é a neoplasia óssea primária mais diagnosticada em pacientes caninos. Este trabalho relata o caso de um canino, com seis anos de idade, sem raça definida, fêmea, não castrado, apresentando OSA em região de palato duro. Ao exame clínico, constatou-se uma massa de consistência firme em região palatina. Além do exame clínico, foram solicitadas radiografias torácicas, exames hematológicos e bioquímicos, exames histopatológicos e tomografia computadorizada. Fora então dado o diagnóstico de OSA condroblástico, e o tumor foi caracterizado pela imuno-histoquímica. Não foram observadas evidências de metástases nesse caso. O tratamento instituído consistiu na combinação de quimioterapia convencional, quimioterapia metronômica e cuidados paliativos, almejando maior sobrevida e bem-estar do paciente, uma vez que a excisão cirúrgica não foi possível devido à localização e à extensão do tumor. Neste artigo, apresentou-se uma caracterização do osteossarcoma com localização incomum no palato duro.(AU)

Use of palatal prosthesis to correct an acquired palatal cleft in a cat: a case report / Utilização do obturador palatino para correção de fenda palatina adquirida em gato: relato de caso

Palatal malformations rarely occur in small animals. Palatal clefts can affect the upper lip, hard palate, and soft palate, and may be congenital or acquired in origin. The most common acquired forms result from the excision of oral neoplasia, teeth extraction, perforating lesions, automobile accidents, and electric accidents. Clinical signs of a fissured palate are sneezing, purulent nasal discharge, salivary secretion in nasal discharge, difficulty feeding and drinking, and pneumonia due to aspiration, which are the most severe alterations and can lead to death. The treatment of palatal clefts consists of occlusion of the oronasal communication, which can be performed using mucoperiosteal grafts, pedicled flaps, or palatal obturators. Herein, we report a case of an acquired palatal cleft treated with a palatal obturator in a feline patient who bit a high-tension wire. Two attempts of surgical correction had been unsuccessful, resulting in suture dehiscence and perpetuation of the oronasal fistula. After fixation of the obturator, the animal showed remission of all clinical signs. The animal has survived for over one year with improved quality of life.(AU)

Os defeitos de palato são ocorrências raras na clínica de pequenos animais. As fendas palatinas podem afetar o lábio superior, palato duro e/ou palato mole, cuja origem pode ser congênita ou adquirida. As formas adquiridas mais comuns são excisão de neoplasias orais, exodontias, lesões perfurantes, acidentes automobilísticos e acidentes com choques elétricos. Os principais sintomas sinais clínicos são espirros, secreção nasal purulenta e salivar, dificuldade de alimentação e ingestão de água sendo a pneumonia por aspiração a alteração mais grave, podendo levar o animal a óbito. O tratamento das fendas consiste na oclusão da comunicação oronasal, que pode ser feita por meio de enxertos mucoperiosteias, flaps pediculados ou com uso de obturadores palatinos. O presente trabalho tem como objetivo relatar o uso de do obturador palatino como método de tratamento de fenda palatina adquirida, em um paciente felino, como causa foi por acidente com fio de alta tensão. Já haviam sido realizadas duas correções cirúrgicas que resultou em deiscência dos pontos e perpetuação da fistula oronasal. Após a fixação do obturador palatino o animal apresentou melhora de todos os sinais clínicos, e da qualidade de vida, e o período de avaliação já superou um ano.(AU)

Tumor ósseo multilobular em um cão / Multilobular tumor of bone in a dog

Background: Multilobular tumor of bone (MTB) is a primary bone neoplasm, uncommon in dogs. This tumor was called ofmany names for a long time, as: chondroma rodens, multilobular osteochondrosarcoma, multilobular osteoma, multilobularchondroma, calcificating aponeurotic fibroma, although MTB was preferred chosen, because these other name could becorrelated with humans’ tumors. This tumor is observed specially in skull bone, although it was reported in zygomaticarc, hard palate, axilla, spine and penis. Mostly happen in big breeds dogs, and middle to old age patients. Clinical signsdepending of region and how aggressive the tumor is, usually are related to compression of any structure. The growth ofMTB is frequently slow and progressive, locally invasive, occurring relapse after surgical revomal, although the tumorhas low to moderate metastatic potential. The aim of this study is to report a case of MTB in a female dog and describeanatomopathological changes.Case: A female dog, mixed breed, 13 year-old, of middleweight was admitted in Pathology Department of College of Agricultural Sciences and Veterinary Medicine (FCAV-Unesp), Campus of Jaboticabal - SP, to be undergone to necropsy. Thepatient have never shown any epileptic crisis or neurologic signs. In macroscopic examination was found a mass in skull,which invaded the orbit and frontal sinus, but it was not invading brain cavity. The neoplasm had and irregular surface, firmconsistent, color was white mixed to red areas, after cut it was granular and rough, and had some point mineralized areas.The lobs of lung had much firm masses, colored gray to white. In cytology it was observed fusiform to polyhedric isolatedmesenchymal cells, moderated pleomorphic, basophilic cytoplasm, thin granulated nuclear chromatin, and visible nucleolithat was involved by eosinophilic extracellular matrix...

Tumor ósseo multilobular em um cão / Multilobular tumor of bone in a dog

Background: Multilobular tumor of bone (MTB) is a primary bone neoplasm, uncommon in dogs. This tumor was called ofmany names for a long time, as: chondroma rodens, multilobular osteochondrosarcoma, multilobular osteoma, multilobularchondroma, calcificating aponeurotic fibroma, although MTB was preferred chosen, because these other name could becorrelated with humans tumors. This tumor is observed specially in skull bone, although it was reported in zygomaticarc, hard palate, axilla, spine and penis. Mostly happen in big breeds dogs, and middle to old age patients. Clinical signsdepending of region and how aggressive the tumor is, usually are related to compression of any structure. The growth ofMTB is frequently slow and progressive, locally invasive, occurring relapse after surgical revomal, although the tumorhas low to moderate metastatic potential. The aim of this study is to report a case of MTB in a female dog and describeanatomopathological changes.Case: A female dog, mixed breed, 13 year-old, of middleweight was admitted in Pathology Department of College of Agricultural Sciences and Veterinary Medicine (FCAV-Unesp), Campus of Jaboticabal - SP, to be undergone to necropsy. Thepatient have never shown any epileptic crisis or neurologic signs. In macroscopic examination was found a mass in skull,which invaded the orbit and frontal sinus, but it was not invading brain cavity. The neoplasm had and irregular surface, firmconsistent, color was white mixed to red areas, after cut it was granular and rough, and had some point mineralized areas.The lobs of lung had much firm masses, colored gray to white. In cytology it was observed fusiform to polyhedric isolatedmesenchymal cells, moderated pleomorphic, basophilic cytoplasm, thin granulated nuclear chromatin, and visible nucleolithat was involved by eosinophilic extracellular matrix...(AU)

Cytological aspects of equine oral fibrosarcoma

Background: Although mesenchymal neoplasms are prominent in horses due to the occurrence of sarcoids, other neoplasmsmay occur. Fibrosarcoma in horses is uncommon, notwithstanding, few studies have performed diagnostic techniques. Itis presumed, therefore, that other diagnostic methodologies should be explored. In this sense, fine needle aspiration cytology (FNAC) emerges as an effective, low-cost, and minimally invasive method to identify tumors in these animals. Theobjective of this study was to describe the use of FNAC in the diagnosis of oral fibrosarcoma in horses. Once fibrosarcomais an aggressive tumor, it is important to validate effective techniques for an early diagnosis.Case: A 10-year-old male Quarter Horse was treated, with a clinical complaint of increased volume in the right maxillaryregion. This tumor occupied about » of the hard palate area. Hyporexia, hypodipsia, mild dehydration, and weight losswere observed at clinical examination. Complementary examinations were requested, and an extensive radiolucent masswith an indication of bone involvement was observed on the radiograph. The hemogram revealed normocytic normochromicanemia, in addition to lymphopenia. In the serum biochemistry test, AST (aspartate aminotransferase) and creatinine wereslightly increased. FNAC showed a malignant mesenchymal neoplasm, possibly fibrosarcoma. Due to its clinical worsening and lack of response to supportive treatment, humanitarian euthanasia was performed. Finally, a histopathologicalexamination confirmed the oral fibrosarcoma suggested by FNAC.Discussion: The early diagnosis of neoplasms is important for its correct treatment, as well as the prognosis. In this way,the combined use of complementary tests helps in the resolution of the case. FNAC is still little used in the examinationroutine in horses. In the present report, this test demonstrated efficacy since it revealed mesenchymal cells compatible withfibroblasts...(AU)

Cytological aspects of equine oral fibrosarcoma

Background: Although mesenchymal neoplasms are prominent in horses due to the occurrence of sarcoids, other neoplasmsmay occur. Fibrosarcoma in horses is uncommon, notwithstanding, few studies have performed diagnostic techniques. Itis presumed, therefore, that other diagnostic methodologies should be explored. In this sense, fine needle aspiration cytology (FNAC) emerges as an effective, low-cost, and minimally invasive method to identify tumors in these animals. Theobjective of this study was to describe the use of FNAC in the diagnosis of oral fibrosarcoma in horses. Once fibrosarcomais an aggressive tumor, it is important to validate effective techniques for an early diagnosis.Case: A 10-year-old male Quarter Horse was treated, with a clinical complaint of increased volume in the right maxillaryregion. This tumor occupied about » of the hard palate area. Hyporexia, hypodipsia, mild dehydration, and weight losswere observed at clinical examination. Complementary examinations were requested, and an extensive radiolucent masswith an indication of bone involvement was observed on the radiograph. The hemogram revealed normocytic normochromicanemia, in addition to lymphopenia. In the serum biochemistry test, AST (aspartate aminotransferase) and creatinine wereslightly increased. FNAC showed a malignant mesenchymal neoplasm, possibly fibrosarcoma. Due to its clinical worsening and lack of response to supportive treatment, humanitarian euthanasia was performed. Finally, a histopathologicalexamination confirmed the oral fibrosarcoma suggested by FNAC.Discussion: The early diagnosis of neoplasms is important for its correct treatment, as well as the prognosis. In this way,the combined use of complementary tests helps in the resolution of the case. FNAC is still little used in the examinationroutine in horses. In the present report, this test demonstrated efficacy since it revealed mesenchymal cells compatible withfibroblasts...

Ulcerative dermatitis caused by feline herpesvirus type 1 in a domestic cat / Dermatite ulcerativa causada por herpesvírus felino tipo 1 em um gato doméstico

A case of ulcerative dermatitis caused by feline herpesvirus type 1 (FeHV-1) in an adult male domestic shorthair cat is reported. The cat was rescued from the streets and presented with ulcerative lesions at the nasal planum and tongue in addition to a history of occasional sneezing. Thirty days after of the first clinical evaluation, the cat died as a result of acute myeloid leukemia. During necropsy, ulcerative lesions were found on the superior lip, the skin of the nasal planum, and at the periorbital region. Ulcerations were also noted on the tongue and hard palate. Histological examination revealed extensive epidermal necrosis, which involved the subjacent dermis and adnexal structures; the inflammatory infiltrate consisted of neutrophils, mast cells, and lymphocytes. Amphophilic intranuclear inclusion bodies were occasionally observed in intact epithelial cells. In the immunohistochemical evaluation, positive intracytoplasmic immunolabeling was detected in the sebaceous and follicular epithelial cells as well as in the bronchiolar epithelial cells. Samples of lymphoid tissue tested positive for the presence of feline leukemia virus and feline immunodeficiency virus by immunohistochemistry. Pulmonary tissue fragments were immunolabeled for feline calicivirus. Samples obtained from a cutaneous lesion were subjected to virus isolation in a cellular culture, which revealed the cytopathic effects characteristic of herpesvirus. FeHV-1 was detected in the samples by polymerase chain reaction.

Descreve-se um caso de dermatite ulcerativa causada por herpesvírus felino tipo 1 (FeHV-1), em um gato adulto, macho, sem raça definida. O gato foi resgatado da rua e apresentava uma lesão ulcerativa no plano nasal e língua, além de espirros esporádicos. Trinta dias após o primeiro atendimento, o gato morreu por leucemia mieloide aguda. Na necropsia, o lábio superior e a pele do plano nasal e periorbital apresentaram extensa lesão ulcerativa, além de ulcerações na língua e no palato duro. Histologicamente havia extensa necrose da epiderme, estendendo-se à derme subjacente e estruturas anexas, associada ao infiltrado inflamatório, constituído por neutrófilos, mastócitos e linfócitos. Observaram-se ainda, ocasionalmente, em células epiteliais intactas, corpúsculos de inclusão intranucleares anfofílicos. Na avaliação imuno-histoquímica anti-FeHV-1 observou-se imunomarcação positiva intracitoplasmática nas células epiteliais e nas células epiteliais bronquiolares. Amostras de tecido linfoide apresentaram imunomarcação para vírus da leucemia felina, vírus da imunodeficiência felina, além de marcação para calicivírus em fragmentos pulmonares. Fragmentos da lesão cutânea foram submetidos a isolamento viral em cultivo celular, onde foi observado efeito citopático característico de herpesvírus e a amostra foi positiva na PCR para FeHV-1.

Tumor ósseo multilobular (Condroma rodens) em um cão / Multilobular tumor of bone (Chondroma rodens) in a dog

Background: The multilobular tumor of bone, also known as chondroma rodens, is a primary tumor of bones with low frequency in dogs. It is considered a slow-growth malignant tumor, locally invasive, able to compress and invade the cerebral tissue. Its occurrence is greater in the flat bones of skull and hard palate. The clinical signs depend on the tumor location and usually are related to the compression of adjacent structures. The aim of this study is present a multilobular tumor of bone clinical case in a dog with has progressive growth on the skull’s frontal part and facial deformation. Clinical, laboratory and therapeutic findings will be discussed in the report. Case: An 8-year-old male crossbred castrated dog, weighing 31 kg, presenting progressive growth in the skull was examined at the University of Caxias do Sul veterinary clinic. According to the owner, the tumor was firstly observed about 3 months ago, and the dog became prostrated since then. In the clinical examination, was noticed an enlarged, symmetric and diffuse volume in the skull’s frontal part, facial deformation, especially around the ocular region, causing visual deficit. It wasn’t detected any other systemic alterations. The radiography of the skull revealed a soft tissue increased volume, suggesting a mass or an encapsulated abscess. Serum biochemistry demonstrated an increase of alcaline phosphatase activity. The other hematological and biochemical parameters were within normal limits. Fine needle aspiration was performed, showing compatible result with bone neoplasm. It was chosen to make a surgical resection, starting with a cross-shaped incision on medial portion of the skull, followed by a skin disclosure to expose the tumor. With the assistance of an orthopedical chisel and metzembaum scissors, the mass was removed. The tumor presented steady and sanded aspect, reddish colored with whitish areas...

Ulcerative dermatitis caused by feline herpesvirus type 1 in a domestic cat / Dermatite ulcerativa causada por herpesvírus felino tipo 1 em um gato doméstico

A case of ulcerative dermatitis caused by feline herpesvirus type 1 (FeHV-1) in an adult male domestic shorthair cat is reported. The cat was rescued from the streets and presented with ulcerative lesions at the nasal planum and tongue in addition to a history of occasional sneezing. Thirty days after of the first clinical evaluation, the cat died as a result of acute myeloid leukemia. During necropsy, ulcerative lesions were found on the superior lip, the skin of the nasal planum, and at the periorbital region. Ulcerations were also noted on the tongue and hard palate. Histological examination revealed extensive epidermal necrosis, which involved the subjacent dermis and adnexal structures; the inflammatory infiltrate consisted of neutrophils, mast cells, and lymphocytes. Amphophilic intranuclear inclusion bodies were occasionally observed in intact epithelial cells. In the immunohistochemical evaluation, positive intracytoplasmic immunolabeling was detected in the sebaceous and follicular epithelial cells as well as in the bronchiolar epithelial cells. Samples of lymphoid tissue tested positive for the presence of feline leukemia virus and feline immunodeficiency virus by immunohistochemistry. Pulmonary tissue fragments were immunolabeled for feline calicivirus. Samples obtained from a cutaneous lesion were subjected to virus isolation in a cellular culture, which revealed the cytopathic effects characteristic of herpesvirus. FeHV-1 was detected in the samples by polymerase chain reaction.(AU)

Descreve-se um caso de dermatite ulcerativa causada por herpesvírus felino tipo 1 (FeHV-1), em um gato adulto, macho, sem raça definida. O gato foi resgatado da rua e apresentava uma lesão ulcerativa no plano nasal e língua, além de espirros esporádicos. Trinta dias após o primeiro atendimento, o gato morreu por leucemia mieloide aguda. Na necropsia, o lábio superior e a pele do plano nasal e periorbital apresentaram extensa lesão ulcerativa, além de ulcerações na língua e no palato duro. Histologicamente havia extensa necrose da epiderme, estendendo-se à derme subjacente e estruturas anexas, associada ao infiltrado inflamatório, constituído por neutrófilos, mastócitos e linfócitos. Observaram-se ainda, ocasionalmente, em células epiteliais intactas, corpúsculos de inclusão intranucleares anfofílicos. Na avaliação imuno-histoquímica anti-FeHV-1 observou-se imunomarcação positiva intracitoplasmática nas células epiteliais e nas células epiteliais bronquiolares. Amostras de tecido linfoide apresentaram imunomarcação para vírus da leucemia felina, vírus da imunodeficiência felina, além de marcação para calicivírus em fragmentos pulmonares. Fragmentos da lesão cutânea foram submetidos a isolamento viral em cultivo celular, onde foi observado efeito citopático característico de herpesvírus e a amostra foi positiva na PCR para FeHV-1.(AU)

Tumor ósseo multilobular (Condroma rodens) em um cão / Multilobular tumor of bone (Chondroma rodens) in a dog

Background: The multilobular tumor of bone, also known as chondroma rodens, is a primary tumor of bones with low frequency in dogs. It is considered a slow-growth malignant tumor, locally invasive, able to compress and invade the cerebral tissue. Its occurrence is greater in the flat bones of skull and hard palate. The clinical signs depend on the tumor location and usually are related to the compression of adjacent structures. The aim of this study is present a multilobular tumor of bone clinical case in a dog with has progressive growth on the skulls frontal part and facial deformation. Clinical, laboratory and therapeutic findings will be discussed in the report. Case: An 8-year-old male crossbred castrated dog, weighing 31 kg, presenting progressive growth in the skull was examined at the University of Caxias do Sul veterinary clinic. According to the owner, the tumor was firstly observed about 3 months ago, and the dog became prostrated since then. In the clinical examination, was noticed an enlarged, symmetric and diffuse volume in the skulls frontal part, facial deformation, especially around the ocular region, causing visual deficit. It wasnt detected any other systemic alterations. The radiography of the skull revealed a soft tissue increased volume, suggesting a mass or an encapsulated abscess. Serum biochemistry demonstrated an increase of alcaline phosphatase activity. The other hematological and biochemical parameters were within normal limits. Fine needle aspiration was performed, showing compatible result with bone neoplasm. It was chosen to make a surgical resection, starting with a cross-shaped incision on medial portion of the skull, followed by a skin disclosure to expose the tumor. With the assistance of an orthopedical chisel and metzembaum scissors, the mass was removed. The tumor presented steady and sanded aspect, reddish colored with whitish areas...(AU)

Oclusão de fístula oronasal em gato com uso somente de resina acrílica autopolimerizável / Oronasal fistula occlusion in cat using only acrylic resin / Oclusión de fístula oronasal en gato con uso sólo de resina acrílica autopolimerizável

A fenda palatina é uma comunicação congênita ou adquirida entre as cavidades oral e nasal, permitindo a passagem de alimentos e líquidos entre elas. O diagnóstico é feito por meio do exame físico da cavidade oral, sendo o tratamento baseado em técnicas cirúrgicas. Relata-se um caso bem-sucedido de oclusão de fístula oronasal utilizando somente resina acrílica autopolimerizável em um felino com histórico de espirros frequentes, secreção nasal purulenta crônica, halitose severa, emagrecimento e trauma sofrido há dois anos, que culminara em fratura da sínfise mandibular corrigida no mesmo período por cerclagem com fios de aço. No exame clínico verificou-se secreção nasal muco-purulenta fétida e a presença de uma grande fístula palatina na extensão do palato duro. Encaminhou-se o paciente para realização dos exames pré-cirúrgicos para posterior correção da fistula oronasal com o uso de resina acrílica autopolimerizavel. O procedimento foi bem sucedido visto que o animal deixou de apresentar os sinais clínicos e voltou a alimentar-se normalmente. A técnica mostrou-se eficaz e de fácil execução para correção de fenda palatina traumática de grande extensão em gato, na qual não se utilizou suturas ou flaps, pois os mesmos não eram praticáveis, podendo ser utilizada em substituição a outros métodos convencionais.(AU)

Cleft palate is a congenital or acquired communication between the oral and nasal cavities which can often contaminate the nasal cavity with saliva or food. The diagnosis is made by physical examination of the oral cavity and it is usually treated with surgery. We report a successful case of oronasal fistula occlusion using only acrylic resin in a feline. The patient presented with a history of frequent sneezing, chronic purulent nasal discharge, severe halitosis, weight loss and facial trauma suffered two years ago. The animal had mandibular symphysis fracture that was corrected by cerclage with steel wires. On clinical examinationit was observedthe presence of smelling nasal mucus, purulent secretions and the presence of a large cleft fistula in the extension of the hard palate. The patient was submitted to surgery in order to repair the oronasal fistula using acrylic resin. The surgery was curative eliminating clinical signs. The technique was effective and easy to be performed in this case of a traumatic cleft palate with large deffect in a cat. This technique can be used to replace other conventional methods, mainly in cases that the use of sutures or flaps are not feasible.(AU)

El paladar hendido es una comunicación congénita o adquirida entre las cavidades oral y nasal, lo que permite el paso de alimentos y líquidos entre ellos. El diagnóstico se realiza mediante un examen físico de la cavidad oral, siendo el tratamiento basado en técnicas quirúrgicas. Presentamos un caso de éxito de oclusión de la fístula oronasal usando sólo la resina acrílica autopolimerizável en un felino con histórico de frecuentes estornudos, secreción nasal purulenta crónica, halitosis severa, pérdida de peso y trauma sufrido hace dos años, culminando en fractura de la sínfisis mandibular, corregida en el mismo período por cerclaje con hilos de acero. En el examen clínico se verificó moco nasal maloliente, secreciones purulentas y la presencia de una gran fístula palatina en la extensión del paladar duro. Se hicieron exámenes pre-quirúrgicos para la posterior corrección de la fístula oronasal, mediante resina acrílica autopolimerizavel. El procedimiento fue exitoso porque el animal dejó de presentar signos clínicos y volvió a alimentarse normalmente. La técnica fue eficaz y de fácil ejecución para corrección de paladar hendido traumático de gran longitud en gato, en la cual no se utilizó suturas o aletas, ya que no eran viables y puede ser utilizado para sustituir a otros métodos convencionales.(AU)

Oclusão de fístula oronasal em gato com uso somente de resina acrílica autopolimerizável / Oronasal fistula occlusion in cat using only acrylic resin / Oclusión de fístula oronasal en gato con uso sólo de resina acrílica autopolimerizável

A fenda palatina é uma comunicação congênita ou adquirida entre as cavidades oral e nasal, permitindo a passagem de alimentos e líquidos entre elas. O diagnóstico é feito por meio do exame físico da cavidade oral, sendo o tratamento baseado em técnicas cirúrgicas. Relata-se um caso bem-sucedido de oclusão de fístula oronasal utilizando somente resina acrílica autopolimerizável em um felino com histórico de espirros frequentes, secreção nasal purulenta crônica, halitose severa, emagrecimento e trauma sofrido há dois anos, que culminara em fratura da sínfise mandibular corrigida no mesmo período por cerclagem com fios de aço. No exame clínico verificou-se secreção nasal muco-purulenta fétida e a presença de uma grande fístula palatina na extensão do palato duro. Encaminhou-se o paciente para realização dos exames pré-cirúrgicos para posterior correção da fistula oronasal com o uso de resina acrílica autopolimerizavel. O procedimento foi bem sucedido visto que o animal deixou de apresentar os sinais clínicos e voltou a alimentar-se normalmente. A técnica mostrou-se eficaz e de fácil execução para correção de fenda palatina traumática de grande extensão em gato, na qual não se utilizou suturas ou flaps, pois os mesmos não eram praticáveis, podendo ser utilizada em substituição a outros métodos convencionais.

Cleft palate is a congenital or acquired communication between the oral and nasal cavities which can often contaminate the nasal cavity with saliva or food. The diagnosis is made by physical examination of the oral cavity and it is usually treated with surgery. We report a successful case of oronasal fistula occlusion using only acrylic resin in a feline. The patient presented with a history of frequent sneezing, chronic purulent nasal discharge, severe halitosis, weight loss and facial trauma suffered two years ago. The animal had mandibular symphysis fracture that was corrected by cerclage with steel wires. On clinical examinationit was observedthe presence of smelling nasal mucus, purulent secretions and the presence of a large cleft fistula in the extension of the hard palate. The patient was submitted to surgery in order to repair the oronasal fistula using acrylic resin. The surgery was curative eliminating clinical signs. The technique was effective and easy to be performed in this case of a traumatic cleft palate with large deffect in a cat. This technique can be used to replace other conventional methods, mainly in cases that the use of sutures or flaps are not feasible.

El paladar hendido es una comunicación congénita o adquirida entre las cavidades oral y nasal, lo que permite el paso de alimentos y líquidos entre ellos. El diagnóstico se realiza mediante un examen físico de la cavidad oral, siendo el tratamiento basado en técnicas quirúrgicas. Presentamos un caso de éxito de oclusión de la fístula oronasal usando sólo la resina acrílica autopolimerizável en un felino con histórico de frecuentes estornudos, secreción nasal purulenta crónica, halitosis severa, pérdida de peso y trauma sufrido hace dos años, culminando en fractura de la sínfisis mandibular, corregida en el mismo período por cerclaje con hilos de acero. En el examen clínico se verificó moco nasal maloliente, secreciones purulentas y la presencia de una gran fístula palatina en la extensión del paladar duro. Se hicieron exámenes pre-quirúrgicos para la posterior corrección de la fístula oronasal, mediante resina acrílica autopolimerizavel. El procedimiento fue exitoso porque el animal dejó de presentar signos clínicos y volvió a alimentarse normalmente. La técnica fue eficaz y de fácil ejecución para corrección de paladar hendido traumático de gran longitud en gato, en la cual no se utilizó suturas o aletas, ya que no eran viables y puede ser utilizado para sustituir a otros métodos convencionales.

Diagnoses of ovine infection by the serotype-4 bluetongue virus on Minas Gerais, Brazil

Background: Bluetongue (BT) is a viral disease transmitted by hematophagous vectors of the genus Culicoides. In Brazil, the identification of antibodies against the virus has been held for over thirty years, however clinicopathological diagnosis of the disease are scarce. The first reported case occurred in the state of Paraná in 2001, confirmed by isolation and identification of serotype 12 of BTV. In the state of Rio Grande do Sul, in 2009, two outbreaks confirmed and was identified the serotype 12. Serotype 4 was isolated during an outbreak in the state of Rio de Janeiro in 2013. This study describes the Diagnoses of ovine infection by the serotype-4 bluetongue virus in Minas Gerais, Brazil. Case: In a farm in the Southern region of the state of Minas Gerais, a group of 28 male sheep, was sent for necropsy at the Setor de Patologia Veterinária of Universidade Federal de Lavras (SPV-UFLA). In a flock of 80 male sheep 28 died with clinical signs of respiratory distress, whereas other showed signs of anemia and hypoproteinemia, cough, sneezing, prostration, fever, mucopurulent nasal discharge, anemia and submandibular edema. At necropsy, the main changes observed were cranioventral pulmonary consolidation, hemorrhage at the base of the pulmonary artery and ulcerating lesions in the hard palate mucosa, rumen and reticulum. The histological changes consisted of bacterial [...]

Diagnoses of ovine infection by the serotype-4 bluetongue virus on Minas Gerais, Brazil

Background: Bluetongue (BT) is a viral disease transmitted by hematophagous vectors of the genus Culicoides. In Brazil, the identification of antibodies against the virus has been held for over thirty years, however clinicopathological diagnosis of the disease are scarce. The first reported case occurred in the state of Paraná in 2001, confirmed by isolation and identification of serotype 12 of BTV. In the state of Rio Grande do Sul, in 2009, two outbreaks confirmed and was identified the serotype 12. Serotype 4 was isolated during an outbreak in the state of Rio de Janeiro in 2013. This study describes the Diagnoses of ovine infection by the serotype-4 bluetongue virus in Minas Gerais, Brazil. Case: In a farm in the Southern region of the state of Minas Gerais, a group of 28 male sheep, was sent for necropsy at the Setor de Patologia Veterinária of Universidade Federal de Lavras (SPV-UFLA). In a flock of 80 male sheep 28 died with clinical signs of respiratory distress, whereas other showed signs of anemia and hypoproteinemia, cough, sneezing, prostration, fever, mucopurulent nasal discharge, anemia and submandibular edema. At necropsy, the main changes observed were cranioventral pulmonary consolidation, hemorrhage at the base of the pulmonary artery and ulcerating lesions in the hard palate mucosa, rumen and reticulum. The histological changes consisted of bacterial [...](AU)

Pythiosis in sheep from Paraná, southern Brazil / Pitiose em ovinos no Paraná, Sul do Brasil

This paper reports pythiosis in a sheep from southwestern Paraná, Brazil, confirmed by indirect ELISA (Enzime-Linked Immunosorbent Assay) and immunohistochemistry, as well as it describes the macro and microscopic injuries, in order to understand the pathogenicity. A 4-year-old ewe from a flock of 30 Santa Inês sheep, raised semi-extensively with access to a weir, showed cachexia, bilateral enlargement in nasal region, a serous and bloody secretion with a fetid odor from its nose and swollen submandibular and retropharyngeal lymph nodes. Blood collection was performed trough jugular vein puncture in order to make complete blood cell count (CBC) and to obtain serum for the subsequent serological examination. As the hematological counts were within the normal range for sheep, the animal was euthanized and submitted to necropsy. Indirect ELISA resulted positive for pythiosis. Necropsy revealed necrosis of the hard palate with a diameter of 3.5cm and extending up to the nasal cavity, forming a fistula. Submandibular and retropharyngeal lymph nodes were enlarged and edematous on section. Microscopic findings for submandibular and retropharyngeal lymph nodes consisted in moderate infiltration of eosinophils mainly in the subcapsular sinus, characterizing reactive eosinophilic lymphadenitis. The nasal cavity revealed rhinitis and oral cavity stomatitis with necro-eosinophilic and pronounced multifocal granulomatous infiltration and presence of hyphae. Hyphae found in palate and nasal cavity were positive for Pythium insidiosum by Grocott's method and immunohistochemistry, the last one considered to be confirmatory for the pathogen diagnostic. This report has an important epidemiological aspect, as it is the first case of pythiosis in sheep confirmed by serology in South Brazil and an alert of possible infection by the pathogen in floodplains.(AU)

Este trabalho tem como objetivo descrever um caso de pitiose confirmado por ELISA (Enzime-Linked Immunosorbent Assay) indireto e imuno-histoquímica em uma ovelha do sudoeste do Paraná, Brasil, bem como suas lesões macro e microscópicas, a fim de compreender a sua patogenicidade. Trata-se de um ovino, fêmea, de 4 anos de idade, de um rebanho de 30 animais, da raça Santa Inês, criados em sistema semiextensivo, com acesso à um açude. O animal vinha apresentando aumento de volume na região do focinho, associado a emagrecimento progressivo. No exame físico apresentou-se caquético, com aumento de volume bilateral na região nasal, e com uma secreção serosanguinolenta de odor fétido fluindo das narinas, além de possuir os linfonodos submandibulares e retrofaríngeos bilateralmente infartados. Foi realizada coleta de sangue por punção da veia jugular para realização do hemograma e obtenção do soro para posterior realização de exame sorológico. Sendo que todos os parâmetros hematológicos analisados estavam dentro dos valores normais para a espécie. Após a realização do exame clínico e da coleta de sangue, o animal foi eutanasiado e procedeu-se a necropsia. Através do Teste de ELISA indireto, a amostra apresentou resultado positivo para pitiose. Na ocasião da necropsia pode-se verificar uma área necrosada de aproximadamente 3,5 cm de diâmetro no palato duro, a qual se estendeu até o assoalho da cavidade nasal formando uma fístula. Os linfonodos submandibulares e retrofaríngeos estavam aumentados de volume e ao corte edematosos. Os achados microscópicos dos linfonodos submandibulares e retrofaríngeos consistiram de quantidade moderada de eosinófilos, principalmente nos seios subcapsulares caracterizando uma linfadenite eosinofílica (reativa). Na cavidade nasal e oral, observou-se, respectivamente, rinite e estomatite necro-eosinofílica e granulomatosa multifocal acentuada associada a hifas intralesionais...(AU)

Fenda palatina em equinos: relato de caso / Cleft Palate in horses: case report / Paladar Hendido en equinos neonatos: case report

A fenda palatina (palatosquise) é uma afecção congênita incomum em equinos jovens. Sua etiologia é desconhecida e caracteriza-se por falha na fusão do processo palatino lateral ocorrido no 47º dia de gestação. A principal sintomatologia é disfagia com descarga nasal alimentar bilateral pós-prandial e o diagnóstico definitivo dá-se por endoscopia das vias aéreas superiores. O prognóstico é melhor em cirurgia de correção da fenda palatina no palato mole quando comparada com a cirurgia no palato duro, mas o objetivo da correção é o mesmo: eliminar o refluxo nasal de alimentos e reduzir o risco de aspiração do conteúdo alimentar. O objetivo do relato de caso é disponibilizar aos profissionais de clínica e cirurgia de equinos informações sobre a incidência, tratamento e complicações dos animais acometidos pela afecção congênita fenda palatina. Um potro, Quarto-de-Milha de 30 dias, apresentando disfagia e leite nas narinas após mamar foi encaminhado ao serviço de cirurgia de grandes animais do Hospital Veterinário da Faculdade de Medicina Veterinária e Zootecnia da USP (HOVET - FMVZ/USP). Mediante endoscopia das vias aéreas superiores, diagnosticou-se fenda palatina. Para correção da palatosquise, optou-se pela técnica cirúrgica faringotomia, que consiste na incisão do osso base-hioide envolvendo o terço caudal do palato mole. Os neonatos apresentam maior incidência de efeitos adversos e alta mortalidade anestésica, portanto a anestesia para correção desta afecção consiste em complicações inerentes aos pacientes dessa idade como maior predisposição à hipoglicemia, hipoxemia e hipoventilação. No dia seguinte ao procedimento, houve desconforto abdominal e encaminhamento à laparotomia exploratória. O animal apresentou diversas complicações e no 11º dia de internação foi realizada a eutanásia. [...]

The cleft palate (palatoschisis) is an uncommon congenital condition in young horses. Its etiology is unknown and is characterized by failure of the fusion of the lateral palatine process occurred on the 47th gestational day. The main symptomatology is dysphagia with bilateral postprandial alimentary nasal discharge and the diagnosis is by upper airways endoscopy. The prognosis is better in soft palate cleft surgery compared to hard palate surgery, but the goal of correction is the same: eliminate nasal reflux of food and reduce aspiration risk of food content. This case report is to provide clinicians and equine surgery professionals information on the incidence, treatment and complications of animals affected the congenital cleft palate. A 30 day old foal,presenting dysphagia and milk in the nostrils after nurse was attended at Large Animals Surgical Service of Veterinary Hospital in Faculty of Veterinary Medicine and Animal Science of USP (HOVET - FMVZ/USP). Upper airways endoscopy revealed a cleft palate. For correction of palatoschisis, the surgeons opted for the surgical technique pharyngotomy, which consists in incision in the base-hyoid bone involving the soft palate ' s caudal third. Neonates are higher incidents of adverse effects and high anesthetic mortality, therefore, anesthesia in this case shows greater predisposition to hypoglycemia, hypoxemia and hypoventilation. One day after soft palate surgery, foal had an abdominal discomfort and referral to exploratory laparotomy. The animal had several complications and on 11th day of hospitalization it was performed in euthanasia. [...]

El paladar hendido (palatosquisis) es una afección congénita poco común en equinos jóvenes. Su etiología es desconocida y se caracteriza por una falia en la fusión del proceso palatino lateral ocurrido en el 470 día de gestación. La principal sintomatología es disfagia con descarga nasal alimentar bilateral post prandial y el diagnóstico definitivo se da por endoscopia de las vías aéreas superiores. El pronóstico es mejor en cirugía de corrección de la hendidura palatina en el paladar blando cuando comparada con la cirugía en el paladar duro, pero el objetivo de la corrección es el mismo: eliminar el reflujo nasal del alimento y reducir los riesgos de aspiración del contenido alimentar. El objetivo del relato del caso es ofrecer a los profesionales de clínica y cirugía de equinos información sobre la incidencia, tratamiento y complicaciones de los animales acometidos por la afección congénita del paladar hendido. Un potro, cuarto de milla de 30 días, presentando disfagia y leche en los orificios nasales después de mamar fue encaminado al servicio de cirugía de grandes animales del Hospital Veterinario de la Facultad de Medicina Veterinaria y Zootecnia de la USP (HOVET - FMVZlUSP). Mediante endoscopia de las vías aéreas superiores, se diagnosticó paladar hendido. Para corregir la palatosquisis, fue elegida la técnica quirúrgica de la faringotomía, que consiste en la incisión del hueso base hioides envolviendo el tercio caudal del paladar blando. Los neonatos presentan mayor incidencia de efectos adversos y alta mortalidad anestésica, por 10 tanto, la anestesia para corrección de esta afección consiste en complicaciones inherentes a los pacientes de esa edad como mayor predisposición a la hipoglucemia, hipoxemia e hipoventilación. Al día siguiente del procedimiento, hubo malestar abdominal y fue encaminado a una laparotomía exploratoria. El animal presentó diversas complicaciones y en el 11 o día de la internación, fue realizada la eutanasia. [...]

Fenda palatina em equinos: relato de caso / Cleft Palate in horses: case report / Paladar Hendido en equinos neonatos: case report

A fenda palatina (palatosquise) é uma afecção congênita incomum em equinos jovens. Sua etiologia é desconhecida e caracteriza-se por falha na fusão do processo palatino lateral ocorrido no 47º dia de gestação. A principal sintomatologia é disfagia com descarga nasal alimentar bilateral pós-prandial e o diagnóstico definitivo dá-se por endoscopia das vias aéreas superiores. O prognóstico é melhor em cirurgia de correção da fenda palatina no palato mole quando comparada com a cirurgia no palato duro, mas o objetivo da correção é o mesmo: eliminar o refluxo nasal de alimentos e reduzir o risco de aspiração do conteúdo alimentar. O objetivo do relato de caso é disponibilizar aos profissionais de clínica e cirurgia de equinos informações sobre a incidência, tratamento e complicações dos animais acometidos pela afecção congênita fenda palatina. Um potro, Quarto-de-Milha de 30 dias, apresentando disfagia e leite nas narinas após mamar foi encaminhado ao serviço de cirurgia de grandes animais do Hospital Veterinário da Faculdade de Medicina Veterinária e Zootecnia da USP (HOVET - FMVZ/USP). Mediante endoscopia das vias aéreas superiores, diagnosticou-se fenda palatina. Para correção da palatosquise, optou-se pela técnica cirúrgica faringotomia, que consiste na incisão do osso base-hioide envolvendo o terço caudal do palato mole. Os neonatos apresentam maior incidência de efeitos adversos e alta mortalidade anestésica, portanto a anestesia para correção desta afecção consiste em complicações inerentes aos pacientes dessa idade como maior predisposição à hipoglicemia, hipoxemia e hipoventilação. No dia seguinte ao procedimento, houve desconforto abdominal e encaminhamento à laparotomia exploratória. O animal apresentou diversas complicações e no 11º dia de internação foi realizada a eutanásia. [...](AU)

The cleft palate (palatoschisis) is an uncommon congenital condition in young horses. Its etiology is unknown and is characterized by failure of the fusion of the lateral palatine process occurred on the 47th gestational day. The main symptomatology is dysphagia with bilateral postprandial alimentary nasal discharge and the diagnosis is by upper airways endoscopy. The prognosis is better in soft palate cleft surgery compared to hard palate surgery, but the goal of correction is the same: eliminate nasal reflux of food and reduce aspiration risk of food content. This case report is to provide clinicians and equine surgery professionals information on the incidence, treatment and complications of animals affected the congenital cleft palate. A 30 day old foal,presenting dysphagia and milk in the nostrils after nurse was attended at Large Animals Surgical Service of Veterinary Hospital in Faculty of Veterinary Medicine and Animal Science of USP (HOVET - FMVZ/USP). Upper airways endoscopy revealed a cleft palate. For correction of palatoschisis, the surgeons opted for the surgical technique pharyngotomy, which consists in incision in the base-hyoid bone involving the soft palate ' s caudal third. Neonates are higher incidents of adverse effects and high anesthetic mortality, therefore, anesthesia in this case shows greater predisposition to hypoglycemia, hypoxemia and hypoventilation. One day after soft palate surgery, foal had an abdominal discomfort and referral to exploratory laparotomy. The animal had several complications and on 11th day of hospitalization it was performed in euthanasia. [...](AU)

El paladar hendido (palatosquisis) es una afección congénita poco común en equinos jóvenes. Su etiología es desconocida y se caracteriza por una falia en la fusión del proceso palatino lateral ocurrido en el 470 día de gestación. La principal sintomatología es disfagia con descarga nasal alimentar bilateral post prandial y el diagnóstico definitivo se da por endoscopia de las vías aéreas superiores. El pronóstico es mejor en cirugía de corrección de la hendidura palatina en el paladar blando cuando comparada con la cirugía en el paladar duro, pero el objetivo de la corrección es el mismo: eliminar el reflujo nasal del alimento y reducir los riesgos de aspiración del contenido alimentar. El objetivo del relato del caso es ofrecer a los profesionales de clínica y cirugía de equinos información sobre la incidencia, tratamiento y complicaciones de los animales acometidos por la afección congénita del paladar hendido. Un potro, cuarto de milla de 30 días, presentando disfagia y leche en los orificios nasales después de mamar fue encaminado al servicio de cirugía de grandes animales del Hospital Veterinario de la Facultad de Medicina Veterinaria y Zootecnia de la USP (HOVET - FMVZlUSP). Mediante endoscopia de las vías aéreas superiores, se diagnosticó paladar hendido. Para corregir la palatosquisis, fue elegida la técnica quirúrgica de la faringotomía, que consiste en la incisión del hueso base hioides envolviendo el tercio caudal del paladar blando. Los neonatos presentan mayor incidencia de efectos adversos y alta mortalidad anestésica, por 10 tanto, la anestesia para corrección de esta afección consiste en complicaciones inherentes a los pacientes de esa edad como mayor predisposición a la hipoglucemia, hipoxemia e hipoventilación. Al día siguiente del procedimiento, hubo malestar abdominal y fue encaminado a una laparotomía exploratoria. El animal presentó diversas complicaciones y en el 11 o día de la internación, fue realizada la eutanasia. [...](AU)