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1.
Braz. j. biol ; 83: 1-7, 2023. tab
Artigo em Inglês | LILACS, VETINDEX | ID: biblio-1468883

Resumo

The low Brazilian productive index and the high demand have aroused interest in the cultivation of lentils, however the legume is little known and needs further studies. The objective of this study was to analyze and identify the effects of treatments with insecticides and fungicides on the physiological quality of lentil seeds, CA-1512 strain. The experiments were conducted in the seed laboratory in a completely randomized design with seven treatments and four replicates. Seed treatment with Thiophanate-methyl; Fluazinam® (180 ml) + Pyraclostrobin; Thiophanate-methyl; Fipronil® (150 ml) promoted higher levels of germination under accelerated aging, lower number of abnormal seedlings and longer lengths of shoot and radicle for the emergence in paper. Treatment with Carboxin; Thiram® (250 ml) + Imidacloprid® (150 ml) allowed a higher value in the first count of germination in sand, lower number of dead seeds under accelerated aging and longer root length, in the emergence in sand. Shoot length in the emergence in sand increased after seed treatment with Metalaxyl-M; Fludioxonil® (75 ml) + Pyraclostrobin; Thiophanate-methyl; Fipronil® (150 ml). Treatments with fungicides and insecticides considerably improved the physiological properties of the seeds, thus being able to guarantee greater phytosanitary qualities in the field, generating healthier seedlings and with protection against possible pests and diseases, and consequently guaranteeing greater productivity.


O baixo índice produtivo brasileiro e a alta demanda têm despertado o interesse no cultivo da lentilha, porém a leguminosa é pouco conhecida e necessita maiores estudos. Objetivou-se neste trabalho analisar e identificar tratamentos com inseticidas e fungicidas na qualidade fisiológica das sementes de lentilha, linhagem CA-1512. Os experimentos foram conduzidos no laboratório de sementes em delineamento inteiramente casualizado com sete tratamentos e quatro repetições. O tratamento de semente com Tiofanato-metílico; Fluazinam® (180 ml) + Piraclosrobina; Tiofanato-metílico; Fipronil® (150 ml) proporcionou índices mais elevados de germinação no envelhecimento acelerado, menor número de plântulas anormais e maior comprimento de parte aérea e radícula, na emergência em papel. O tratamento com Carboxina; Tiram® (250 ml) + Imidacloprido® (150 ml) possibilitou maior índice na primeira contagem de germinação em areia, menor número de sementes mortas no envelhecimento acelerado e maior comprimento de raiz, na emergência em areia. Já o comprimento da parte aérea, na emergência em areia, aumentou com o tratamento de semente Metalaxil-M; Fludioxonil® (75 ml) + Piraclosrobina; Tiofanato-metílico; Fipronil® (150 ml). Os tratamentos com fungicidas e inseticidas melhoraram consideravelmente as propriedades fisiológicas das sementes, podendo assim, garantir maiores qualidades fitossanitárias à campo, gerando plântulas mais sadias e com proteção para possíveis pragas e doenças, e consequentemente garantindo maiores produtividades.


Assuntos
Fungicidas Industriais/administração & dosagem , Inseticidas/administração & dosagem , Lens (Planta)/efeitos dos fármacos , Lens (Planta)/fisiologia , Sementes/crescimento & desenvolvimento
2.
Braz. J. Biol. ; 83: 1-7, 2023. tab
Artigo em Inglês | VETINDEX | ID: vti-765460

Resumo

The low Brazilian productive index and the high demand have aroused interest in the cultivation of lentils, however the legume is little known and needs further studies. The objective of this study was to analyze and identify the effects of treatments with insecticides and fungicides on the physiological quality of lentil seeds, CA-1512 strain. The experiments were conducted in the seed laboratory in a completely randomized design with seven treatments and four replicates. Seed treatment with Thiophanate-methyl; Fluazinam® (180 ml) + Pyraclostrobin; Thiophanate-methyl; Fipronil® (150 ml) promoted higher levels of germination under accelerated aging, lower number of abnormal seedlings and longer lengths of shoot and radicle for the emergence in paper. Treatment with Carboxin; Thiram® (250 ml) + Imidacloprid® (150 ml) allowed a higher value in the first count of germination in sand, lower number of dead seeds under accelerated aging and longer root length, in the emergence in sand. Shoot length in the emergence in sand increased after seed treatment with Metalaxyl-M; Fludioxonil® (75 ml) + Pyraclostrobin; Thiophanate-methyl; Fipronil® (150 ml). Treatments with fungicides and insecticides considerably improved the physiological properties of the seeds, thus being able to guarantee greater phytosanitary qualities in the field, generating healthier seedlings and with protection against possible pests and diseases, and consequently guaranteeing greater productivity.(AU)


O baixo índice produtivo brasileiro e a alta demanda têm despertado o interesse no cultivo da lentilha, porém a leguminosa é pouco conhecida e necessita maiores estudos. Objetivou-se neste trabalho analisar e identificar tratamentos com inseticidas e fungicidas na qualidade fisiológica das sementes de lentilha, linhagem CA-1512. Os experimentos foram conduzidos no laboratório de sementes em delineamento inteiramente casualizado com sete tratamentos e quatro repetições. O tratamento de semente com Tiofanato-metílico; Fluazinam® (180 ml) + Piraclosrobina; Tiofanato-metílico; Fipronil® (150 ml) proporcionou índices mais elevados de germinação no envelhecimento acelerado, menor número de plântulas anormais e maior comprimento de parte aérea e radícula, na emergência em papel. O tratamento com Carboxina; Tiram® (250 ml) + Imidacloprido® (150 ml) possibilitou maior índice na primeira contagem de germinação em areia, menor número de sementes mortas no envelhecimento acelerado e maior comprimento de raiz, na emergência em areia. Já o comprimento da parte aérea, na emergência em areia, aumentou com o tratamento de semente Metalaxil-M; Fludioxonil® (75 ml) + Piraclosrobina; Tiofanato-metílico; Fipronil® (150 ml). Os tratamentos com fungicidas e inseticidas melhoraram consideravelmente as propriedades fisiológicas das sementes, podendo assim, garantir maiores qualidades fitossanitárias à campo, gerando plântulas mais sadias e com proteção para possíveis pragas e doenças, e consequentemente garantindo maiores produtividades.(AU)


Assuntos
Lens (Planta)/efeitos dos fármacos , Lens (Planta)/fisiologia , Sementes/crescimento & desenvolvimento , Fungicidas Industriais/administração & dosagem , Inseticidas/administração & dosagem
3.
Braz. j. biol ; 83: e247360, 2023. tab
Artigo em Inglês | LILACS, VETINDEX | ID: biblio-1350301

Resumo

Abstract Excessive intake of non-steroidal anti-inflammatory drugs such as, diclofenac sodium (DS) may lead to toxicity in the rats. In this work, we aimed to examine the protective impact of lentil extract (LE) and folic acid (FA) on the hematological markers, the kidney tissue oxidative stress and the renal function against diclofenac sodium (DS) in male albino rats. The rats (120-150 g) were divided into four equal groups randomly, the first group kept as the untreated control. The second group was administrated with DS (11.6 mg/kg b.wt. orally once/day). The third group was received DS+FA (11.6 mg/kg b.wt.+76.9 microgram/kg b.wt.) orally once/day. The fourth group was treated with DS+LE (11.6 mg/kg b.wt.+500 mg/kg b.wt.) orally once/day. After four weeks, the results revealed that DS produced a significant decrease in the values of red blood cells (RBCs), hemoglobin concentration (Hb), hematocrit (HCT) and white blood cells (WBCs). On the other hand, there was a significant increase in the platelets count. Also, DS induced a renal deterioration; this was evidenced by the significant increase in the serum levels of urea, creatinine, uric acid, Na, Ca, Mg as well as the nitric oxide (NO) level in the kidney tissue. Also, there were a significant reduction in the serum levels of potassium (K) and reduced glutathione (GSH) in the kidney homogenates. Moreover, the findings in the rats treated by DS+LE or DS+FA showed a potential protection on the hematological markers, oxidative stress in the kidney tissue and the renal function disturbed by DS. LE and FA could play a potent role for the prevention the adverse hematological, the kidney tissue oxidative stress and the renal dysfunction caused by DS via their anti-oxidative and bioactive phytochemicals.


Resumo A ingestão excessiva de anti-inflamatórios não esteroidais, como o diclofenaco de sódio (DS), pode causar toxicidade em ratos. Neste trabalho, objetivamos examinar o impacto protetor do extrato de lentilha (LE) e ácido fólico (AF) em marcadores hematológicos, no estresse oxidativo do tecido renal e na função renal contra o diclofenaco de sódio (DS) em ratos albinos machos. Os ratos (120-150 g) foram divididos em quatro grupos iguais aleatoriamente, sendo o primeiro grupo mantido como controle não tratado. O segundo grupo foi administrado com DS (11,6 mg / kg de peso corporal por via oral uma vez / dia). O terceiro grupo recebeu DS + FA (76,9 mg / kg de peso corporal por via oral uma vez / dia). O quarto grupo foi tratado com DS + LE (500 mg / kg de peso corporal por via oral uma vez / dia). Após quatro semanas, os resultados revelaram que o DS produziu uma diminuição significativa nos valores de glóbulos vermelhos (RBCs), concentração de hemoglobina (Hb), hematócrito (HCT) e glóbulos brancos (WBCs). Por outro lado, houve um aumento significativo na contagem de plaquetas. Além disso, o DS induziu uma deterioração renal; isso foi evidenciado pelo aumento significativo dos níveis séricos de ureia, creatinina, ácido úrico, Na, Ca, Mg e também do nível de óxido nítrico no tecido renal. Além disso, houve uma redução significativa nos níveis séricos de potássio (K) e glutationa reduzida (GSH) nos homogenatos renais. Além disso, os achados nos ratos tratados com DS + LE ou DS + FA mostraram uma proteção potencial sobre os marcadores hematológicos, estresse oxidativo no tecido renal e função renal perturbada pelo DS. LE e AF podem desempenhar um papel potente na prevenção do estresse hematológico adverso, do estresse oxidativo do tecido renal e da disfunção renal causada pelo DS por meio de seus fitoquímicos antioxidantes e bioativos.


Assuntos
Animais , Ratos , Diclofenaco/toxicidade , Lens (Planta) , Extratos Vegetais/farmacologia , Estresse Oxidativo , Ácido Fólico , Antioxidantes
4.
Braz. j. biol ; 83: 1-8, 2023. tab
Artigo em Inglês | LILACS, VETINDEX | ID: biblio-1469005

Resumo

Excessive intake of non-steroidal anti-inflammatory drugs such as, diclofenac sodium (DS) may lead to toxicity in the rats. In this work, we aimed to examine the protective impact of lentil extract (LE) and folic acid (FA) on the hematological markers, the kidney tissue oxidative stress and the renal function against diclofenac sodium (DS) in male albino rats. The rats (120-150 g) were divided into four equal groups randomly, the first group kept as the untreated control. The second group was administrated with DS (11.6 mg/kg b.wt. orally once/day). The third group was received DS+FA (11.6 mg/kg b.wt.+76.9 microgram/kg b.wt.) orally once/day. The fourth group was treated with DS+LE (11.6 mg/kg b.wt.+500 mg/kg b.wt.) orally once/day. After four weeks, the results revealed that DS produced a significant decrease in the values of red blood cells (RBCs), hemoglobin concentration (Hb), hematocrit (HCT) and white blood cells (WBCs). On the other hand, there was a significant increase in the platelets count. Also, DS induced a renal deterioration; this was evidenced by the significant increase in the serum levels of urea, creatinine, uric acid, Na, Ca, Mg as well as the nitric oxide (NO) level in the kidney tissue. Also, there were a significant reduction in the serum levels of potassium (K) and reduced glutathione (GSH) in the kidney homogenates. Moreover, the findings in the rats treated by DS+LE or DS+FA showed a potential protection on the hematological markers, oxidative stress in the kidney tissue and the renal function disturbed by DS. LE and FA could play a potent role for the prevention the adverse hematological, the kidney tissue oxidative stress and the renal dysfunction caused by DS via their anti-oxidative and bioactive phytochemicals.


A ingestão excessiva de anti-inflamatórios não esteroidais, como o diclofenaco de sódio (DS), pode causar toxicidade em ratos. Neste trabalho, objetivamos examinar o impacto protetor do extrato de lentilha (LE) e ácido fólico (AF) em marcadores hematológicos, no estresse oxidativo do tecido renal e na função renal contra o diclofenaco de sódio (DS) em ratos albinos machos. Os ratos (120-150 g) foram divididos em quatro grupos iguais aleatoriamente, sendo o primeiro grupo mantido como controle não tratado. O segundo grupo foi administrado com DS (11,6 mg / kg de peso corporal por via oral uma vez / dia). O terceiro grupo recebeu DS + FA (76,9 mg / kg de peso corporal por via oral uma vez / dia). O quarto grupo foi tratado com DS + LE (500 mg / kg de peso corporal por via oral uma vez / dia). Após quatro semanas, os resultados revelaram que o DS produziu uma diminuição significativa nos valores de glóbulos vermelhos (RBCs), concentração de hemoglobina (Hb), hematócrito (HCT) e glóbulos brancos (WBCs). Por outro lado, houve um aumento significativo na contagem de plaquetas. Além disso, o DS induziu uma deterioração renal; isso foi evidenciado pelo aumento significativo dos níveis séricos de ureia, creatinina, ácido úrico, Na, Ca, Mg e também do nível de óxido nítrico no tecido renal. Além disso, houve uma redução significativa nos níveis séricos de potássio (K) e glutationa reduzida (GSH) nos homogenatos renais. Além disso, os achados nos ratos tratados com DS + LE ou DS + FA mostraram uma proteção potencial sobre os marcadores hematológicos, estresse oxidativo no tecido renal e função renal perturbada pelo DS. LE e AF podem desempenhar um papel potente na prevenção do estresse hematológico adverso, do estresse oxidativo do tecido renal e da disfunção renal causada pelo DS por meio de seus fitoquímicos antioxidantes e bioativos.


Assuntos
Masculino , Animais , Ratos , Diclofenaco/toxicidade , Estresse Oxidativo , Lens (Planta) , Rim/efeitos dos fármacos , Testes Hematológicos , Ácido Fólico/farmacologia
5.
Braz. J. Biol. ; 83: 1-8, 2023. tab
Artigo em Inglês | VETINDEX | ID: vti-765582

Resumo

Excessive intake of non-steroidal anti-inflammatory drugs such as, diclofenac sodium (DS) may lead to toxicity in the rats. In this work, we aimed to examine the protective impact of lentil extract (LE) and folic acid (FA) on the hematological markers, the kidney tissue oxidative stress and the renal function against diclofenac sodium (DS) in male albino rats. The rats (120-150 g) were divided into four equal groups randomly, the first group kept as the untreated control. The second group was administrated with DS (11.6 mg/kg b.wt. orally once/day). The third group was received DS+FA (11.6 mg/kg b.wt.+76.9 microgram/kg b.wt.) orally once/day. The fourth group was treated with DS+LE (11.6 mg/kg b.wt.+500 mg/kg b.wt.) orally once/day. After four weeks, the results revealed that DS produced a significant decrease in the values of red blood cells (RBCs), hemoglobin concentration (Hb), hematocrit (HCT) and white blood cells (WBCs). On the other hand, there was a significant increase in the platelets count. Also, DS induced a renal deterioration; this was evidenced by the significant increase in the serum levels of urea, creatinine, uric acid, Na, Ca, Mg as well as the nitric oxide (NO) level in the kidney tissue. Also, there were a significant reduction in the serum levels of potassium (K) and reduced glutathione (GSH) in the kidney homogenates. Moreover, the findings in the rats treated by DS+LE or DS+FA showed a potential protection on the hematological markers, oxidative stress in the kidney tissue and the renal function disturbed by DS. LE and FA could play a potent role for the prevention the adverse hematological, the kidney tissue oxidative stress and the renal dysfunction caused by DS via their anti-oxidative and bioactive phytochemicals.(AU)


A ingestão excessiva de anti-inflamatórios não esteroidais, como o diclofenaco de sódio (DS), pode causar toxicidade em ratos. Neste trabalho, objetivamos examinar o impacto protetor do extrato de lentilha (LE) e ácido fólico (AF) em marcadores hematológicos, no estresse oxidativo do tecido renal e na função renal contra o diclofenaco de sódio (DS) em ratos albinos machos. Os ratos (120-150 g) foram divididos em quatro grupos iguais aleatoriamente, sendo o primeiro grupo mantido como controle não tratado. O segundo grupo foi administrado com DS (11,6 mg / kg de peso corporal por via oral uma vez / dia). O terceiro grupo recebeu DS + FA (76,9 mg / kg de peso corporal por via oral uma vez / dia). O quarto grupo foi tratado com DS + LE (500 mg / kg de peso corporal por via oral uma vez / dia). Após quatro semanas, os resultados revelaram que o DS produziu uma diminuição significativa nos valores de glóbulos vermelhos (RBCs), concentração de hemoglobina (Hb), hematócrito (HCT) e glóbulos brancos (WBCs). Por outro lado, houve um aumento significativo na contagem de plaquetas. Além disso, o DS induziu uma deterioração renal; isso foi evidenciado pelo aumento significativo dos níveis séricos de ureia, creatinina, ácido úrico, Na, Ca, Mg e também do nível de óxido nítrico no tecido renal. Além disso, houve uma redução significativa nos níveis séricos de potássio (K) e glutationa reduzida (GSH) nos homogenatos renais. Além disso, os achados nos ratos tratados com DS + LE ou DS + FA mostraram uma proteção potencial sobre os marcadores hematológicos, estresse oxidativo no tecido renal e função renal perturbada pelo DS. LE e AF podem desempenhar um papel potente na prevenção do estresse hematológico adverso, do estresse oxidativo do tecido renal e da disfunção renal causada pelo DS por meio de seus fitoquímicos antioxidantes e bioativos.(AU)


Assuntos
Animais , Masculino , Ratos , Rim/efeitos dos fármacos , Diclofenaco/toxicidade , Ácido Fólico/farmacologia , Lens (Planta) , Testes Hematológicos , Estresse Oxidativo
6.
Acta sci. vet. (Impr.) ; 51(supl.1): Pub. 883, 2023. ilus
Artigo em Português | VETINDEX | ID: biblio-1437116

Resumo

Background: Persistent hyperplastic primary vitreous is a rare ocular condition that is usually unilateral, formed when normal regression of the hyaloid vascular system does not occur. Diagnosis is possible through ultrasonography, by obtaining images that provide information and also serve as a differential diagnosis. Clinically the condition presents with signs of leukocoria, microphthalmia, and cataracts, and it can be further classified into 6 degrees according to the evolution. The objective of this work is to describe the case and treatment of a canine of the Pointer breed that presented opacity in both eyes, with diagnosis confirmed through ocular ultrasonography. Case: A 6-year-old male pointer dog, weighing 27 kg, was referred to the Veterinary Medical Teaching Hospital of the Federal University of Santa Maria (UFRGS), Santa Maria, RS - Brazil with a history of blindness. According to the owner, the animal's right eye has always been "white", since it was a puppy and the left eye began to present the same characteristic a short time ago. On ophthalmological examination, neither eye showed signs of ocular discomfort, the Schirmer's tear test was within the range expected for the species, fluorescein and threat tests were negative, and a positive pupillary reflex was observed in the left eye. The right eye had total corneal opacity associated with a chronic lesion and the presence of pigment cells in the medial portion of the eyeball, the opacity making it impossible to visualize the other internal structures of the eyeball. The left eye presented lens opacity. In the ultrasound of the right eye, there were several alterations, the presence of a triangular-shaped hyperechogenic structure in the vitreous chamber, a decrease in the depth of the anterior chamber, and the presence of abnormality in the development of the lens. The findings are compatible with and confirmed the diagnosis of PHPV. In the left eye, the ultrasound images indicated hyperechogenicity of the posterior and anterior poles of the lens, findings compatible with cataracts. Through the animal's history, complete ophthalmic examination, and use of ocular ultrasonography, it was possible to diagnose and differentiate the causes of the white eye in the patient. The preoperative screening was continued with an electroretinography examination, which showed a satisfactory electrical response for the retina of the left eye and an unsatisfactory electrical response for the retina of the right eye. Phacoemulsification surgery was performed to remove the cataract in the left eye with intraocular lens implantation. The positive threat reflex returned in this eye, with a return of visual acuity. Discussion: Persistent hyperplastic tunica lentis and persistent hyperplastic primary vitreous (PHTVL/PHPV) are congenital anomalies caused by a failure to regress the fetal hyaloid vasculature. These conditions are not common, but occur sporadically in dogs. The PHPV classification can be classified into degrees, based on the morphological aspect of the lesion. Following this classification scheme, the PHPV of the animal in question refers to the 6th degree of evolution. The total opacity of the cornea in the right eye was associated with the presence of a hyperplastic primary vitreous and the leukocoria in the left eye was due to the presence of a mature cataract. The conclusion of the diagnosis was only possible through ocular ultrasonography, which is very useful to differentiate the causes of ocular opacity and leukocoria, in addition to allowing complete evaluation of the intraocular structures and being considered an essential exam to confirm the diagnosis of PHPV.


Assuntos
Animais , Masculino , Cães , Catarata/veterinária , Olho/diagnóstico por imagem , Vítreo Primário Hiperplásico Persistente/veterinária , Anormalidades do Olho/veterinária
7.
Braz. j. biol ; 832023.
Artigo em Inglês | LILACS-Express | LILACS, VETINDEX | ID: biblio-1469099

Resumo

Abstract The low Brazilian productive index and the high demand have aroused interest in the cultivation of lentils, however the legume is little known and needs further studies. The objective of this study was to analyze and identify the effects of treatments with insecticides and fungicides on the physiological quality of lentil seeds, CA-1512 strain. The experiments were conducted in the seed laboratory in a completely randomized design with seven treatments and four replicates. Seed treatment with Thiophanate-methyl; Fluazinam® (180 ml) + Pyraclostrobin; Thiophanate-methyl; Fipronil® (150 ml) promoted higher levels of germination under accelerated aging, lower number of abnormal seedlings and longer lengths of shoot and radicle for the emergence in paper. Treatment with Carboxin; Thiram® (250 ml) + Imidacloprid® (150 ml) allowed a higher value in the first count of germination in sand, lower number of dead seeds under accelerated aging and longer root length, in the emergence in sand. Shoot length in the emergence in sand increased after seed treatment with Metalaxyl-M; Fludioxonil® (75 ml) + Pyraclostrobin; Thiophanate-methyl; Fipronil® (150 ml). Treatments with fungicides and insecticides considerably improved the physiological properties of the seeds, thus being able to guarantee greater phytosanitary qualities in the field, generating healthier seedlings and with protection against possible pests and diseases, and consequently guaranteeing greater productivity.


Resumo O baixo índice produtivo brasileiro e a alta demanda têm despertado o interesse no cultivo da lentilha, porém a leguminosa é pouco conhecida e necessita maiores estudos. Objetivou-se neste trabalho analisar e identificar tratamentos com inseticidas e fungicidas na qualidade fisiológica das sementes de lentilha, linhagem CA-1512. Os experimentos foram conduzidos no laboratório de sementes em delineamento inteiramente casualizado com sete tratamentos e quatro repetições. O tratamento de semente com Tiofanato-metílico; Fluazinam® (180 ml) + Piraclosrobina; Tiofanato-metílico; Fipronil® (150 ml) proporcionou índices mais elevados de germinação no envelhecimento acelerado, menor número de plântulas anormais e maior comprimento de parte aérea e radícula, na emergência em papel. O tratamento com Carboxina; Tiram® (250 ml) + Imidacloprido® (150 ml) possibilitou maior índice na primeira contagem de germinação em areia, menor número de sementes mortas no envelhecimento acelerado e maior comprimento de raiz, na emergência em areia. Já o comprimento da parte aérea, na emergência em areia, aumentou com o tratamento de semente Metalaxil-M; Fludioxonil® (75 ml) + Piraclosrobina; Tiofanato-metílico; Fipronil® (150 ml). Os tratamentos com fungicidas e inseticidas melhoraram consideravelmente as propriedades fisiológicas das sementes, podendo assim, garantir maiores qualidades fitossanitárias à campo, gerando plântulas mais sadias e com proteção para possíveis pragas e doenças, e consequentemente garantindo maiores produtividades.

8.
Acta sci. vet. (Impr.) ; 51(supl.1): Pub. 891, 2023. ilus
Artigo em Português | VETINDEX | ID: biblio-1444407

Resumo

Background: Taurine is an essential amino acid for cats and its deficiency causes an ocular disorder called taurine deficiency retinopathy. The retinal lesion is definitive and can be classified into five progression stages. In an advanced stage, it leads to blindness that in most cases is irreversible. This disease is considered rare as taurine is currently supplemented in commercial cat food. The objective of this report is to describe the ophthalmic changes in a cat with advanced taurine deficiency retinopathy, a rare but current disease that is important for differential diagnosis of blindness in cats. Case: We report the case of an adult mixed-breed cat (weighing 3.4 kg), that was attended by the Ophthalmology Service of the College of Veterinary Medicine and Animal Science (UNESP - Botucatu), which was treated due to complaints of poor visual acuity for about 1 year. The animal, which was previously a stray animal, had been adopted for 2 years and provided premium cat food ad libitum. Ophthalmic examination showed bilateral mydriasis, with negative menace, direct pupillary, and consensual light reflexes. No change was observed in the ocular appendages, cornea, anterior chamber, lens, and vitreous humor. The eyes were normotensive and fluorescein test negative. Direct and indirect fundoscopy revealed an area of ellipsoidal hyperreflexia with darkened margins laterally to the optic nerve disk in the tapetal region and intense retinal vascular attenuation in both eyes, with a diagnosis of taurine deficiency retinopathy. Complete blood count and biochemical analysis parameters were within the normal range, including the leukocyte count. The guardian was instructed to continue feeding the cat balanced cat food and received information on the proper care and management of a blind animal. Discussion: Although taurine deficient retinopathy is currently underdiagnosed due to the supplementation of this amino acid in commercial cat food, animals that are not properly fed, such as those receiving dog food or homemade food, may be deficient in this amino acid. Taurine deficiency and in this case, the consequent taurine deficiency retinopathy, was diagnosed by visualizing the lesion characteristic of this amino acid deficit since no other retinal change presents this aspect in cats. Therefore, this lesion is considered pathognomonic of this deficiency. Hyperreflective retinal lesions with darkened margins indicate the slow chronic progression in the already stabilized lesions. The animal in this report presented pigmented lesion margins, indicating the chronicity of these retinal changes. Moreover, lesion signs are visible on fundoscopy only after a period of 2-11 months of nutritional amino acid deficiency, and complete retinal atrophy usually occurs after at least nine months of taurine deficiency. Thus, complete blindness associated with advanced retinal changes reinforced the suspicion that the animal had taurine deficiency for a prolonged period of time prior to its adoption. Its guardian was instructed to provide balanced commercial cat food, because although retinal lesions are irreversible, cardiac changes resulting from taurine deficiency are reversed with dietary supplementation. In addition, taurine deficiency affects other organs and systems, such as the central nervous, immune, and reproductive systems. In conclusion, although taurine deficiency retinopathy is currently rare, this condition should be considered one of the possible differential diagnoses for blindness in feline patients.


Assuntos
Animais , Feminino , Gatos , Retina/lesões , Doenças Retinianas/veterinária , Taurina/análise , Aminoácidos
9.
Acta sci. vet. (Impr.) ; 50(supl.1): Pub. 801, 2022. ilus
Artigo em Inglês | VETINDEX | ID: biblio-1401304

Resumo

Background: A cataract is an opacity of the crystalline structure that results in impaired vision. The congenital form manifests itself at birth or shortly thereafter and might also be inherited and therefore capable of passing on to descendants. Cataracts can be caused by systemic diseases, medications, toxic substances, radiation, metabolic alterations, dietary deficiencies, inflammation, traumatic injuries, age, or genetic factors. The few Blackbelly sheep herds are located in the northeast and north regions of Brazil and are considered rare, which could result in high levels of consanguinity. In this context, we report a case of congenital cataract in a Blackbelly lamb and its possible etiology. Case: A 3-month-old lamb presented with ophthalmic alterations since birth, with white and cloudy spots in both eyes and impaired vision. In the same herd, 3 elderly sheep showed similar ophthalmic alterations. The lamb was able to follow its dam, but when walking, bumped into small objects or very close to his vision field. The lamb managed to follow the herd and dodge large objects, suggesting partial vision loss. During a physical examination, both lens showed opacity and reduced corneal reflex, pupillary reflex to direct light, pupillary reflex to consensual light, and threat reflex. Ultrasonographic examination revealed that both lens presented hyperechogenicity. Hematological values were within the reference limits. In the same herd, three elderly sheep presented bilateral cataracts (2 rams and 1 ewe) in previous years, which at that time was attributed to natural aging. One ram was the lamb's grandfather. The other ram was the father of the female, both with cataracts. Based on history, physical examination, and complementary examinations, the lamb was diagnosed with bilateral congenital cataracts with a probable hereditary condition. Discussion: Multiple factors can be related to the etiology of cataracts, and it can be difficult to establish the correct etiology. Regarding the age of onset, cataracts can be classified mainly as congenital and senile. Senile cataract is a bilateral opacification process that involves the entire lens, with slow progression and gradual loss of vision with increasing age. In adult sheep, the high proportion of eyes affected by spontaneously arising cataracts could be related to age, increased exposure to sunlight, increased genetic susceptibility, or a combination of these factors. In this case, the herd had three adult elderly sheep with cataracts previously characterized as senile. However, after reviewing the genealogy, it was found that all animals had some degree of parentage, suggesting a hereditary factor. Congenital cataracts are expressed soon after birth, resulting from the malformation of fibers in the lens, and are generally nonprogressive. The congenital form may or may not be associated with hereditary factors. Inheritance cataracts have been reported in several breeds of dogs and usually occur as an autosomal recessive trait. Blackbelly sheep are rare in Brazil, favoring consanguinity, so we believe that cataracts are inherited in this herd. To control this ophthalmic alteration, all animals with crystalline opacities were excluded from reproduction, and the herd should be monitored in future cases.


Assuntos
Animais , Catarata/congênito , Catarata/etiologia , Ovinos , Cristalino/anormalidades
10.
Acta sci. vet. (Impr.) ; 50(supl.1): Pub. 811, 2022. ilus
Artigo em Português | VETINDEX | ID: biblio-1401420

Resumo

Background: Fibroepithelial polyps are benign tumors of mesenchymal and ectodermal origin. Regarding the localization related to the cutaneous region, they may affect the eyelid and periocular area. In veterinary medicine, polyps located in the urethra of dogs and monkeys, vagina of bitches and on the skin have been described. Fibroepithelial polyps may present as single to multiple nodules, exophytic to pedunculated, usually arising on a smooth surface of a common base. The aim of this paper is to describe the ocular and histopathological changes of a corneal fibroepithelial polyp of recurrent character in a dog. Case: A 20-year-old Lhasa Apso dog, with a history of progressive corneal neoformation in the right eye for 4 months. Patient was submitted to routine ophthalmic evaluation. At biomicroscopy, a discrete mucopurulent discharge was observed in the nasal corner, a nodule in the lower eyelid (± 3 mm), moderate conjunctival hyperemia, vascularization and corneal edema between 12 and 5 h, presence of a pinkish proliferative mass in 3 h, affecting the anterior stroma and opacity of the lens, Schirmer's Tear Test (STT) 20 mm/min and intraocular pressure (IOP) 10 mm/Hg. In the left eye, the STT and IOP were within normal range (17 mm/min and 11 mg/Hg, respectively) and at biomicroscopy only lens opacity was observed. Given the presence of the neoformation in the cornea, the patient underwent lamellar keratectomy to excise the mass and third eyelid flap. The tissue was then submitted to histopathology. The histopathological examination showed a proliferation of fibrous component with areas presenting reactive fibroblasts, with acidophilic cytoplasm and with little volume and slight neovascularization, presence of hyperplasia of the lining epithelium and cells with round to oval nuclei, with inconspicuous nucleoli, compatible with fibroepithelial polyp, without evidence of malignancy. After 18 months, the patient presented recurrence of the condition with a history of slow evolution (about ten months). The ophthalmic evaluation showed lesions very similar to the initial one, describing a recurrence of the lesion. Discussion: Corneal neoplasms are uncommon in dogs. The clinical findings in patients with ocular neoplasms include irregular to nodular masses, gray to reddish in color, and typically associated with a vascular supply. These features are related to the type of tumor and its degree of evolution. There are reports in the literature of ocular neoplasms such as squamous cell carcinoma, papilloma, melanocytoma, fibrosarcoma, hemangiosarcoma, melanoma, lymphoma. Related to fibroepithelial polyp with ocular involvement, there are rare reports in human literature and none in veterinary medicine. There is a human description of the presence of a polyp affecting the cornea associated with a corneal dermoid and e other cases of polyps of conjunctival origin. As far as treatment is concerned, the polyp should be surgically removed because of the possibility of recurrence, tissue metaplasia, or even transformation into a malignant tumor, as seen in the case reported here, in which even with surgical removal there was recurrence and metaplasia of the cells. Based on the histopathological findings, it can be concluded that this is a fibroepithelial polyp with a recidivating characteristic, not well described in the veterinary literature, with an atypical presentation affecting the cornea.


Assuntos
Animais , Cães , Neoplasias Fibroepiteliais/veterinária , Doenças da Córnea/veterinária , Neoplasias Oculares/veterinária
11.
Arq. bras. med. vet. zootec. (Online) ; 74(5): 807-813, Sep.-Oct. 2022. tab, ilus
Artigo em Inglês | VETINDEX | ID: biblio-1403410

Resumo

The purpose of this paper is to determine the ocular echobiometry and investigate its correlation with cranial and body morphometric parameters in 50 adult Shih Tzu dogs. The echobiometric measurements of the anterior chamber (AC), vitreous chamber (VC), lens axial thickness (LTA), transverse lens thickness (LTT), and axial length of the eyeball (ALE) were obtained by two-dimensional ultrasonography. Morphometric measurements of bizygomatic distance (BDIST), frontal-occipital distance (FOD), withers height (WH), thoracic circumference (TC), and body length (BL) were also obtained. The mean of the AC depth was 2.83±0.50mm, the VC was 9.18±0.54mm, the LTA was 6.42±0.32mm and the LTT was 9.17±1.18mm, while the mean of the ALE was 18.82±0.66mm. There was no correlation between ocular echobiometric variables and cranial and body morphometric variables in adult dogs of the Shih Tzu breed, as well as no significant difference of these variables when considering gender and age of the dogs (p ≥ 0.05).


Objetivou-se, com este estudo, a determinação da ecobiometria ocular e a investigação de sua correlação com parâmetros morfométricos cranianos e corporais em 50 cães Shih Tzu adultos. As medidas ecobiométricas da câmara anterior (CA), da câmara vítrea (CV), da espessura axial (ELA), da transversal da lente (ETL) e do comprimento axial do globo ocular (CGO) foram obtidas por meio da ultrassonografia em modo bidimensional. As medidas morfométricas do distanciamento bizigomático (DBZ), do distanciamento fronto-occipital (DFO), da altura de cernelha (AC), da circunferência torácica (CT) e do comprimento corporal (CP) também foram obtidas. A média da profundidade de CA foi de 2,83±0,50mm, da CV foi de 9,18±0,54mm, da ELA foi de 6,42±0,32mm e da ETL foi de 9,17±1,18mm, enquanto a média do CGO foi de 18,82±0,66mm. Não foi verificada correlação entre as variáveis ecobiométricas oculares e as morfométricas cranianas e corporais em cães adultos da raça Shih Tzu, assim como não houve diferença significativa dessas variáveis quando considerado o gênero e a idade dos cães (P≥0,05).


Assuntos
Animais , Cães , Corpo Vítreo/anatomia & histologia , Cefalometria/veterinária , Biometria , Câmara Anterior/anatomia & histologia , Ultrassonografia/veterinária
12.
Acta sci. vet. (Impr.) ; 50(suppl.1): Pub.746-4 jan. 2022. ilus
Artigo em Português | VETINDEX | ID: biblio-1458554

Resumo

Background: There is no hope of preserving vision at the terminal stage of glaucoma, and surgical treatment is indicated in thesecases. Among the various surgical techniques used, eye evisceration with implantation of an intrascleral prosthesis provide thebest cosmetic results. Even though eye evisceration with prosthesis implantation represents an excellent treatment option forterminal glaucoma, reports on the use of this technique in dogs are scarce in the current literature. The aim of this work is to reporta case of a dog with end-stage glaucoma subjected to eye evisceration surgery and implantation of an intrascleral prosthesis.Case: A 7-year-old bitch mixed breed with a history of glaucoma secondary to uveitis with no response to medical therapy wasreferred to the Ophthalmology service of the University Veterinary Hospital of Coimbra (HVUC), Portugal At the ophthalmicexamination, the glaucomatous left eye was buphthalmic, with congested episcleral blood vessels, mydriasis, and posterior luxation of the lens; there was no response to threat or obfuscation, no direct and consensual pupillary reflex, nor pupillary reflexesto chromatic light. The intraocular pressure (IOP) was 55 mmHg, and the Schirmer’s tear test (STT-1) result was 19 mm/min.Ophthalmoscopy revealed attenuated retinal blood vessels and a pale optic papilla with mild excavation. The right eye wasfunctional, with all parameters assessed on examination and by tests within the normal ranges for the species. An ultrasoundexamination of the left eye confirmed the presence of posterior luxation of the lens and buphthalmia in the absence of intraocularneoplasm. In view of the patient’s history and results of the clinical examinations, a surgical approach was indicated to treat theglaucomatous eye. The patient’s tutor requested a surgical procedure that...


Assuntos
Animais , Cães , Evisceração do Olho/métodos , Evisceração do Olho/veterinária , Olho Artificial/veterinária , Silicones , Glaucoma/veterinária
13.
Acta sci. vet. (Online) ; 50(suppl.1): Pub. 746, 31 jan. 2022. ilus
Artigo em Português | VETINDEX | ID: vti-31785

Resumo

Background: There is no hope of preserving vision at the terminal stage of glaucoma, and surgical treatment is indicated in thesecases. Among the various surgical techniques used, eye evisceration with implantation of an intrascleral prosthesis provide thebest cosmetic results. Even though eye evisceration with prosthesis implantation represents an excellent treatment option forterminal glaucoma, reports on the use of this technique in dogs are scarce in the current literature. The aim of this work is to reporta case of a dog with end-stage glaucoma subjected to eye evisceration surgery and implantation of an intrascleral prosthesis.Case: A 7-year-old bitch mixed breed with a history of glaucoma secondary to uveitis with no response to medical therapy wasreferred to the Ophthalmology service of the University Veterinary Hospital of Coimbra (HVUC), Portugal At the ophthalmicexamination, the glaucomatous left eye was buphthalmic, with congested episcleral blood vessels, mydriasis, and posterior luxation of the lens; there was no response to threat or obfuscation, no direct and consensual pupillary reflex, nor pupillary reflexesto chromatic light. The intraocular pressure (IOP) was 55 mmHg, and the Schirmers tear test (STT-1) result was 19 mm/min.Ophthalmoscopy revealed attenuated retinal blood vessels and a pale optic papilla with mild excavation. The right eye wasfunctional, with all parameters assessed on examination and by tests within the normal ranges for the species. An ultrasoundexamination of the left eye confirmed the presence of posterior luxation of the lens and buphthalmia in the absence of intraocularneoplasm. In view of the patients history and results of the clinical examinations, a surgical approach was indicated to treat theglaucomatous eye. The patients tutor requested a surgical procedure that...(AU)


Assuntos
Animais , Cães , Olho Artificial/veterinária , Evisceração do Olho/métodos , Evisceração do Olho/veterinária , Silicones , Glaucoma/veterinária
14.
Arq. bras. med. vet. zootec. (Online) ; 74(4): 585-591, July-Aug. 2022. tab, ilus
Artigo em Inglês | VETINDEX | ID: biblio-1393905

Resumo

The objective of this study was to establish ophthalmic parameters in the Pomeranian dog breed. Schirmer tear test (STT), tear breakup time test (TBUTT), Jones test (JT), aesthesiometry, biomicroscopy, tonometry, non-contact specular microscopy (SM), ophthalmoscopy and ultrasonography (US) were carried out 48 eyes of 24 male and female Pomeranian dogs from a breeding kennel. Descriptive statistics was applied for data analysis. Means and standard errors found for STT, TBUT, JT, esthesiometry and tonometry were 24.310±0.448mm/min, 14.570±0.406s., 8.420±1.571min, 3.667±0.157cm and 17.960±0.697mmHg, respectively. For biomicroscopy, 43.75% of the eyes presented caruncle trichiasis, 25% chromodacryorrhea, 25% medial entropion and 10,42% distichiasis. SM showed endothelial cells density of 1958.285±36.760 cells/mm². For hexagonality, endothelial cells area and central corneal thickness were 62.229±2.183%, 519.231±9.853mm², 0.567±0.006mm, respectively. Ophthalmoscopy presented a pattern described in other breeds. Amelanotic fundus was reported in 8.33% of the eyes. The US means and standard errors for axial length of the eyeball, lens thickness, anterior and vitreous chamber depth were 16.859±0.148mm, 6.651±0.081mm, 2.673±0.091mm and 7.485±0.101mm. Mild changes in the lacrimal evaluation parameters were influenced by eyelid changes in STT type I. Increased corneal sensitivity was observed in the breed.


O objetivo do estudo foi estabelecer os parâmetros oftálmicos na raça Spitz Alemão anão. Realizaram-se teste lacrimal de Schirmer (TLS), tempo de ruptura do filme lacrimal (TRFL), teste de Jones (TJ), estesiometria, biomicroscopia, tonometria, microscopia especular (MS), oftalmoscopia e ultrassonografia (US) em 48 olhos de 24 cães machos e fêmeas da raça Sptiz Alemão anão, oriundos de canil de criação. Aplicou-se estatística descritiva. As médias e erros padrões encontrados para TLS, TRL, TJ, estesiometria e tonometria foram 24,310±0,448mm/min, 14,570±0,406s., 8,420±1,571min, 3,667±0,157cm e 17,960±0,697mmHg, respectivamente. À biomicroscopia, 43,75% dos olhos apresentaram triquíase de carúncula, 25% cromodacriorreia, 25% entrópio de canto medial e 10,42% distiquíases. À MS, os valores para densidade das células endoteliais, hexagonalidade, área das células endoteliais e espessura corneal central foram 1958,285±36,760 cells/mm², 62,229±2,183%, 519,231±9,853mm² e 0,567±0,006mm, respectivamente. À oftalmoscopia, padrão conforme descrito para cães. Fundo amelanótico foi reportado em 8,33% das retinas. Ao US, os valores identificados para diâmetro axial horizontal, espessura da lente, profundidade das câmaras anterior e posterior foram 16,859±0,148mm, 6,651±0,081mm, 2,673±0,091mm and 7,485±0,101mm. Leves alterações nos parâmetros lacrimais foram influenciadas por alterações palpebrais no TLS tipo I. Sensibilidade corneana aumentada foi identificada na raça.


Assuntos
Animais , Cães , Oftalmologia , Animais de Estimação , Aparelho Lacrimal
15.
Acta sci. vet. (Impr.) ; 50(supl.1): Pub. 827, 2022. ilus
Artigo em Português | VETINDEX | ID: biblio-1401642

Resumo

Background: Episcleral inflammation may be assumed to be primary immune-mediated, secondary to intra- or extraocular diseases, or systemic abnormalities. We aimed to report a confirmed and another suspect case of nodular episclerokeratites (NEK) due to its rarity in the clinical setting and the paucity of case reports in Brazilian literature. Cases: Case 1. Refers to a 7-year-old castrated male, Collie-mixed breed, presenting with epiphora and an irregular ocular surface shape in the left eye (LE). Ophthalmic evaluation of this eye revealed mucoid discharge, conjunctival hyperemia, episcleral injection, and a gelatinous mass in the temporal limbic region. Biomicroscopic evaluation of the anterior chamber, lens, and vitreous was impaired in the LE because of corneal vessels and a mild flare in the aqueous humor. Histopathology of a scleral biopsy revealed the presence of lymphocytes, histiocytes, and some plasma cells. Positive CD3-lymphocytes were observed by immunohistochemistry, confirming the diagnosis of NEK. Case 2. Refers to a 8-year-old, spayed female Border Collie with a history of exophthalmos, conjunctival hyperemia, and inability to close the eyelid of the LE. During ophthalmic examination, an irregular espicleral nodule of approximately 9 mm was also found in the temporal limbic region, along with enlargement of episcleral vessels and scleral thinning at the equatorial region. The cornea showed mild and diffuse edema, and white crystal-like deposits were distributed in a band-like fashion at the dorsal aspect. Ultrasonography revealed scleral thinning without evidence of a mass effect arising from the iris, ciliary body, or retrobulbar space. Based on these findings, NEK was suspected. In both cases, the clinical signs reduced significantly after seven days of topical treatment with corticosteroids and cyclosporine. Discussion: It is assumed that scleral disorders are primarily immune mediated. However, such conditions may develop secondary to ocular trauma (surgery and foreign bodies), Ehrlichia canis, and Onchocerca spp. Infections and situations were ruled out in both cases. In case 1, additional histological and immunohistochemical findings supported a primary and immune-mediated scleral disease. Although the definitive diagnosis was not confirmed by histology in case 2, one can assume that the episcleral inflammation may have arisen due to an immune-mediated disorder once the eye responded positively to corticosteroid therapy. Additionally, secondary glaucoma was excluded as a possible diagnosis in case 2, because the intraocular pressure of the affected eye was below the reference range for dogs, coupled with the irregular appearance of the episclera, which is not characteristic of canine glaucoma. Moreover, in case 2, because remission of the masses of neoplastic origin after corticotherapy was not expected, the tumor was discarded. NEK has a characteristic ploriferative behavior and resistance to topical immunosuppression; clinical recurrence was not observed in the LE of either patient who remained on treatment after 60 days of follow-up. Regarding prognosis, one study showed a correlation between cellular contingent and therapeutic responses. The percentage of positive CD79a cells (B-lymphocytes) was significantly higher in cases of epicleritis and NEK, in which a poor response was achieved after topical immunosuppressive treatment. As shown by the veterinary literature and the cases described here, the complete remission of NEK is more common in unilateral cases, as confirmed after a 12-month follow-up. The 2 reported cases are useful for clarifying the common findings, diagnosis, and long-term management of NEK. Scleral abnormalities, such as NEK, must be included in the list of differential diagnoses of glaucoma, neoplasia, and endophthalmitis during ophtalmic examination.


Assuntos
Animais , Cães , Esclera/patologia , Uveíte/veterinária , Ceratite/veterinária , Tolerância Imunológica
16.
Acta sci. vet. (Impr.) ; 50: Pub.1853-2022. ilus, tab
Artigo em Inglês | VETINDEX | ID: biblio-1458528

Resumo

Background: The tumor microenvironment is an important target of studies in different types of neoplasms. Understanding the role of general components such as immune, vascular and fibroblastic cells has the objective of contributing to prognosis and treatment. The aim of this study was to evaluate the relationship between mast cells and angiogenesis in benign and malignant mammary neoplasms by investigating the role of degranulation and microlocation of mast cells and neoformed vessels in canine mammary neoplasms. Materials, Methods & Results: Mammary glands (n = 122) from 50 female dogs submitted to mastectomy without chemotherapy were evaluated and categorized into 3 groups: control group (n = 46); malignant group (n = 57) and benign group (n = 19). Lymph nodes without changes (n = 59) and with metastases (n = 6) were also evaluated. To evaluate the MCD (mast cell density) and angiogenesis, Toluidine Blue (0.1%) and Gomori’s Trichrome techniques were performed and adapted from previous studies. Photomicrographs of 10 hotspot areas on a 40x objective lens of the mammary glands and lymph nodes were captured to assess MCD and angiogenesis. In the absence of these areas, random fields were captured. For the mammary glands of the malignant and benign groups, 20 fields were analyzed, as the analysis considered the microlocation (peritumoral and intratumoral). Counting was performed manually using ImageJ software version 1.42q by 2 observers. The statistical analysis were performed using SPSS software version 19.0. The most frequent histological type in the malignant group was carcinoma in mixed tumor (68.42%; 39/57) and in the benign group was benign mixed tumor (57.89%; 11/19). Female dogs without breed pattern were more frequently affected represented 70% of the animals and the mean age was 9 years and 8 months ± 3 years and 1 month...


Assuntos
Feminino , Animais , Cães , Mastócitos/patologia , Microambiente Tumoral , Neoplasias Mamárias Animais/patologia , Neoplasias Mamárias Animais/ultraestrutura , Neovascularização Patológica/veterinária
17.
Acta sci. vet. (Online) ; 50: Pub. 1853, Jan. 24, 2022. ilus, tab
Artigo em Inglês | VETINDEX | ID: vti-765298

Resumo

Background: The tumor microenvironment is an important target of studies in different types of neoplasms. Understanding the role of general components such as immune, vascular and fibroblastic cells has the objective of contributing to prognosis and treatment. The aim of this study was to evaluate the relationship between mast cells and angiogenesis in benign and malignant mammary neoplasms by investigating the role of degranulation and microlocation of mast cells and neoformed vessels in canine mammary neoplasms. Materials, Methods & Results: Mammary glands (n = 122) from 50 female dogs submitted to mastectomy without chemotherapy were evaluated and categorized into 3 groups: control group (n = 46); malignant group (n = 57) and benign group (n = 19). Lymph nodes without changes (n = 59) and with metastases (n = 6) were also evaluated. To evaluate the MCD (mast cell density) and angiogenesis, Toluidine Blue (0.1%) and Gomoris Trichrome techniques were performed and adapted from previous studies. Photomicrographs of 10 hotspot areas on a 40x objective lens of the mammary glands and lymph nodes were captured to assess MCD and angiogenesis. In the absence of these areas, random fields were captured. For the mammary glands of the malignant and benign groups, 20 fields were analyzed, as the analysis considered the microlocation (peritumoral and intratumoral). Counting was performed manually using ImageJ software version 1.42q by 2 observers. The statistical analysis were performed using SPSS software version 19.0. The most frequent histological type in the malignant group was carcinoma in mixed tumor (68.42%; 39/57) and in the benign group was benign mixed tumor (57.89%; 11/19). Female dogs without breed pattern were more frequently affected represented 70% of the animals and the mean age was 9 years and 8 months ± 3 years and 1 month...(AU)


Assuntos
Animais , Feminino , Cães , Neoplasias Mamárias Animais/patologia , Neoplasias Mamárias Animais/ultraestrutura , Microambiente Tumoral , Mastócitos/patologia , Neovascularização Patológica/veterinária
18.
Ciênc. Anim. (Impr.) ; 31(01): 160-168, 2021. ilus
Artigo em Português | VETINDEX | ID: biblio-1472693

Resumo

As afecções oculares são diagnosticadas rotineiramente em clínica de animais domésticos, tornando a oftalmologia um relevante seguimento na Medicina Veterinária. A catarata é caracterizada pela opacidade progressiva docristalino que interfere na absorção de luz que chegará à retina. O objetivo deste trabalho é relatar o caso de tratamento cirúrgico de catarata imatura pela técnica de facoemulsificação com implante de lente intraocular em canino. Um canino, macho, não castrado, da raça poodle, com 14 anos de idade, foi atendido em uma clínica veterinária, na cidade de Manaus, Amazonas. Após diagnóstico, optou-se pela cirurgia através da técnica de facoemulsificação, visando a remoção por meio da fragmentação e aspiração do cristalino, com posterior implante da lente intraocular. Decorridos 30 dias da cirurgia, o paciente retornou para a avalição da evolução do tratamento. Observou-se melhora significativa na visão do animal. Por conseguinte, conclui-se que a técnica foi eficiente no processo de recuperação, de acordo com o progresso significativo dos testes de reflexo, colocação de obstáculos em ambientes escuros e claros.


Eye disorders are routinely diagnosed in domestic animal clinic, which makes ophthalmology a relevant follow up in Veterinary Medicine. Cataracts are characterized by a progressive opacity of the lens that interferes with the absorption of light reaching the retina. The objective of this work is to report the case of surgical treatment of immature cataract using the phacoemulsification technique with intraocular lens implant in canines. A 14-year-oldmale poodle, uncastrated, was seen at a veterinary clinic in the city of Manaus, Amazonas. After diagnosis, surgery was performed using the phacoemulsification technique, aiming at the removal through fragmentation and aspiration of the lens with subsequent implantation of the intraocular lens. After 30 days of the surgery, the patient returned to evaluate the progress of the treatment. A significant improvement in the animal's vision was observed. Therefore, it was concluded that the technique used was an efficient in the recovery process according to significant advances, two reflection tests, placing obstacles in dark and light environments.


Assuntos
Masculino , Animais , Cães , Catarata/diagnóstico , Catarata/reabilitação , Catarata/veterinária , Doenças do Cão/cirurgia , Doenças do Cão/diagnóstico , Doenças do Cão/tratamento farmacológico , Facoemulsificação/veterinária
19.
Ci. Anim. ; 31(01): 160-168, 2021. ilus
Artigo em Português | VETINDEX | ID: vti-31914

Resumo

As afecções oculares são diagnosticadas rotineiramente em clínica de animais domésticos, tornando a oftalmologia um relevante seguimento na Medicina Veterinária. A catarata é caracterizada pela opacidade progressiva docristalino que interfere na absorção de luz que chegará à retina. O objetivo deste trabalho é relatar o caso de tratamento cirúrgico de catarata imatura pela técnica de facoemulsificação com implante de lente intraocular em canino. Um canino, macho, não castrado, da raça poodle, com 14 anos de idade, foi atendido em uma clínica veterinária, na cidade de Manaus, Amazonas. Após diagnóstico, optou-se pela cirurgia através da técnica de facoemulsificação, visando a remoção por meio da fragmentação e aspiração do cristalino, com posterior implante da lente intraocular. Decorridos 30 dias da cirurgia, o paciente retornou para a avalição da evolução do tratamento. Observou-se melhora significativa na visão do animal. Por conseguinte, conclui-se que a técnica foi eficiente no processo de recuperação, de acordo com o progresso significativo dos testes de reflexo, colocação de obstáculos em ambientes escuros e claros.(AU)


Eye disorders are routinely diagnosed in domestic animal clinic, which makes ophthalmology a relevant follow up in Veterinary Medicine. Cataracts are characterized by a progressive opacity of the lens that interferes with the absorption of light reaching the retina. The objective of this work is to report the case of surgical treatment of immature cataract using the phacoemulsification technique with intraocular lens implant in canines. A 14-year-oldmale poodle, uncastrated, was seen at a veterinary clinic in the city of Manaus, Amazonas. After diagnosis, surgery was performed using the phacoemulsification technique, aiming at the removal through fragmentation and aspiration of the lens with subsequent implantation of the intraocular lens. After 30 days of the surgery, the patient returned to evaluate the progress of the treatment. A significant improvement in the animal's vision was observed. Therefore, it was concluded that the technique used was an efficient in the recovery process according to significant advances, two reflection tests, placing obstacles in dark and light environments.(AU)


Assuntos
Animais , Masculino , Cães , Doenças do Cão/diagnóstico , Doenças do Cão/tratamento farmacológico , Doenças do Cão/cirurgia , Catarata/diagnóstico , Catarata/reabilitação , Catarata/veterinária , Facoemulsificação/veterinária
20.
Pesqui. vet. bras ; 41: e06598, 2021. tab, graf
Artigo em Inglês | LILACS, VETINDEX | ID: biblio-1340345

Resumo

Objective was to evaluate the accuracy of elastography in the differentiation between normal and cataract lenses One hundred forty-five eyes of 98 dogs were divided into groups according to cataract stage. Forty-twoeyes were submitted to phacoemulsification. Biometric parameters, echogenicity and echotexture patterns of the anterior, posterior and vitreous chambers, lens and retina-choroid-sclera complexes were evaluated by ocular ultrasound in modes A and B. Deformability, and color (blue color = indicated less rigid structures, color red = more rigid structures) of the lenses were evaluated by the elastogram. The shear wave velocity (SWV; m/s) was calculated in three regions of the lens, both in the cortex and in the nucleus. The SWV of nucleus was statistically different between the normal lenses and with cataracts, and between the stages of cataract (P<0.001). Healthy lenses and incipient cataracts had a more rigid nucleus. Mature cataracts presented lowest nuclear rigidity (P<0.001). On cortical region the SWV was significantly higher (P<0.01) in intumescent and incipient cataracts. SWV less than 2.67m/s indicates cataract with a sensitivity of 72% and specificity of 94%. Values lower than 2.23m/s suggest mature cataract, with sensitivity of 71% and specificity of 76%. SWV greater than 2.66 m/s are associated with normal lenses or incipient cataract, presenting sensitivity of 94% and specificity of 84%. Qualitative method allowed differentiation between healthy and affected lenses and the classification of evolutionary stages. There was a correlation between the degree of stiffness of lens in cortical and nuclear regions (p=00165, r=0.37) and between the balanced saline solution quantitative and surgical time (P<0.01, r=0.73). Degree of stiffness of lens did not correlate with parameters of phacoemulsification. Elastographic proved feasible for evaluating the lens of dogs, characterizing the types of cataracts, and demonstrating increased stiffness of the diseased lenses.(AU)


O objetivo foi avaliar a precisão da elastografia na diferenciação entre lentes normais e de catarata. Cento e quarenta e cinco olhos de 98 cães foram divididos em grupos de acordo com o estágio de maturação da catarata. Quarenta e dois olhos foram submetidos à facoemulsificação. Parâmetros biométricos, ecogenicidade e padrões de ecotextura das câmaras anterior, posterior e vítrea, lente e complexos retina-coróide-esclera foram avaliados por ultrassonografia ocular nos modos A e B. A deformabilidade e a coloração (cor azul = indicou estruturas menos rígidas, cor vermelha = estruturas mais rígidas) das lentes foram avaliadas pelo elastograma. A velocidade da onda de cisalhamento (SWV; m/s) foi calculada em três regiões da lente, tanto no córtex quanto no núcleo. A SWV do núcleo foi estatisticamente diferente entre as lentes normais e com catarata e entre os estágios da catarata (P<0,001). Lentes saudáveis e cataratas incipientes tinham um núcleo mais rígido. Cataratas maduras apresentaram menor rigidez nuclear (P<0,001). Na região cortical, a SWV foi significativamente maior (P<0,01) nas cataratas intumescentes e incipientes. Uma SWV menor que 2,67m/s indica catarata com sensibilidade de 72% e especificidade de 94%. Valores inferiores a 2,23m/s sugerem catarata madura, com sensibilidade de 71% e especificidade de 76%. Uma SWV superior a 2,66m/s está associada à catarata normal ou incipiente, apresentando sensibilidade de 94% e especificidade de 84%. O método qualitativo permitiu a diferenciação entre lentes normais de olhos saudáveis e afetadas e a classificação dos estágios evolutivos. A elastografia se mostrara uma ferramenta viável para avaliar as lentes de cães, caracterizando os tipos de catarata e demonstrando maior rigidez das lentes doentes.(AU)


Assuntos
Masculino , Cães , Catarata/veterinária , Cães , Técnicas de Imagem por Elasticidade/veterinária , Ultrassom , Facoemulsificação
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