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Atividade antibacteriana de nanopartículas de polipirrol diante de Staphylococcus aureus isolados de amostras de leite de vacas e cabras com mastite / Antibacterial behavior of polypyrrole nanoparticles against Staphylococcus aureus isolated from cows and goats with mastitis

Acosta, A. C; Santos, A. S; Silva, F. A. G; Medeiros, E. S; Oliveira, H. P. de; Costa, M. M; Fernandes, A. W. C; Pinheiro Júnior, J. W; Mota, R. A.
Arq. bras. med. vet. zootec. (Online); 72(3): 1047-1050, May-June, 2020. ilus
Artigo em Português | LILACS | ID: biblio-1129749

Resumo

The aim of the present study was to evaluate the antibacterial behavior of polypyrrole nanoparticles (PPy-NPs) in water against biofilm producer or not S. aureus isolated from cows and goats with mastitis. One hundred and thirty-eight isolates of S. aureus were initially evaluated for biofilm formation by spectrophotometry in microplates. In addition, the minimum inhibition concentration (MIC) and minimum bactericidal concentration (MBC) of PPy-NPs in water for planktonic S. aureus were determined. From the bovine samples analyzed, 5 (4.46%) S. aureus isolates showed a strong biofilm production, 17 (15.18%) moderate production, 36 (32.14%) with weak production and 54 (48.21%) did not produce biofilms. Strains from goats (26) showed no biofilm production in 18 (69.23%) strains and weak biofilm production in 8 (30.76%) strains. The MIC and MBC of S. aureus to PPy-NPs were found in the same concentration (125搭/mL) in all strains tested, regardless of biofilm production or not. This finding provides a new insight into the interaction between PPy-NPs and S. aureus, and will offer potential benefits for the control of mastitis.(AU)
Biblioteca responsável: BR68.1