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Study on the Major Genes Related with Fat Deposition in Liver and Abdominal Fat of Different Breeds of Chicken
Kang, X; Amevor, F. K; Zhang, L; Shah, A. M; Zhu, Q; Tian, Y; Shu, G; Wang, Y; Zhao, X.
Afiliação
  • Kang, X; Sichuan Agricultural University. Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province. Sichuan Province. CN
  • Amevor, F. K; Sichuan Agricultural University. Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province. Sichuan Province. CN
  • Zhang, L; Sichuan Agricultural University. Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province. Sichuan Province. CN
  • Shah, A. M; Sichuan Agricultural University. Animal Nutrition Institute. Chengdu. CN
  • Zhu, Q; Sichuan Agricultural University. Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province. Sichuan Province. CN
  • Tian, Y; Sichuan Agricultural University. Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province. Sichuan Province. CN
  • Shu, G; Sichuan Agricultural University. Department of Basic Veterinary Medicine. Chengdu. CN
  • Wang, Y; Sichuan Agricultural University. Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province. Sichuan Province. CN
  • Zhao, X; Sichuan Agricultural University. Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province. Sichuan Province. CN
Rev. bras. ciênc. avic ; 24(1): eRBCA-2020-1373, 2022. tab, ilus, graf
Article em En | VETINDEX | ID: biblio-1368402
Biblioteca responsável: BR68.1
ABSTRACT
Fat deposition is higher in fast growing chickens than in slow growing chickens. The liver is the major organ for lipogenesis and fat deposition in chickens, although genetic background, age, and gender also influence fat deposition. In the present study, we aimed to explore the molecular mechanisms underlying fat deposition in liver and abdominal fat. We determined the expression abundances of the key genes regulating fat metabolism in fast-growing (FG) broilers (Cobb) and slow-growing (SG) broilers (HS1) and found that ACC, FAS, PGC-1α, PPARγ, SREBP-1c and PLIN1genes were expressed in the abdominal fat and liver tissues of FG and SG. ANOVA analysis showed that the breed, age, and tissue factors influenced the expressions of ACC, FAS, PGC-1α, PPARγ, SREBP-1c, and PLIN1 genes in the liver and abdominal fat of FG and SG. Also, the expressions of PPARγ and PLIN1 in the liver of SG were higher than that of FG. The results suggest that the differences in adipocyte development and adipose deposition between breeds are due to genetic factors.(AU)
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Texto completo: 1 Base de dados: VETINDEX Idioma: En Revista: Rev. bras. ciênc. avic Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: VETINDEX Idioma: En Revista: Rev. bras. ciênc. avic Ano de publicação: 2022 Tipo de documento: Article