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Genome-Wide Association Study of Abdominal Fat in Wenshang Barred Chicken Based on the Slaf-Seq Technology
Liu, W; Liu, J; Zhou, Y; Cao, D; Lei, Q; Han, H; Wang, J; Li, D; Gao, J; Li, H; Li, Fuwei.
Afiliação
  • Liu, W; Poultry Breeding Engineering Technology Center. Shandong. CN
  • Liu, J; Poultry Breeding Engineering Technology Center. Shandong. CN
  • Zhou, Y; Poultry Breeding Engineering Technology Center. Shandong. CN
  • Cao, D; Poultry Breeding Engineering Technology Center. Shandong. CN
  • Lei, Q; Poultry Breeding Engineering Technology Center. Shandong. CN
  • Han, H; Poultry Breeding Engineering Technology Center. Shandong. CN
  • Wang, J; Poultry Breeding Engineering Technology Center. Shandong. CN
  • Li, D; Poultry Breeding Engineering Technology Center. Shandong. CN
  • Gao, J; Poultry Breeding Engineering Technology Center. Shandong. CN
  • Li, H; Poultry Institute. Shandong Academy of Agricultural Sciences. Jinan. CN
  • Li, Fuwei; Poultry Breeding Engineering Technology Center. Shandong. CN
Rev. bras. ciênc. avic ; 24(4): eRBCA-2021-1612, 2022. ilus, tab, graf
Article em En | VETINDEX | ID: biblio-1415641
Biblioteca responsável: BR68.1
ABSTRACT
Chicken abdominal fat (AF) is an economically important trait, and many studies have been conducted on genetic selection for AF. However, previous studies have focused on detecting functional chromosome mutations or regions using gene chips. The present study used the specific-locus amplified fragment sequencing (SLAF-seq) technology to perform a genome-wide association study (GWAS) on purebred Wengshang Barred chicken. A total of 1,286,715 single-nucleotide polymorphisms (SNPs) were detected, and 175,211 SNPs were selected as candidate SNPs for genome-wide association analysis using TASSEL general linear models. Two SNPs markers reached genome-wide significance. Of these, rs7943847, rs127627362 were significantly associated with AF at 120 days. These SNPs are close to eight genes (SLC16A6, ARSG, WIPI1, PRKAR1A, FAM20A, ABCA8, ABCA9, CPQ,). These results would enrich the studies on AF and promote the use of Chinese chicken, especially the Wenshang Barred chicken.(AU)
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Texto completo: 1 Base de dados: VETINDEX Idioma: En Revista: Rev. bras. ciênc. avic Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: VETINDEX Idioma: En Revista: Rev. bras. ciênc. avic Ano de publicação: 2022 Tipo de documento: Article