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Hematological and biochemical changes in a cow with metastatic cholangiocarcinoma
Beserra, Lucas Alencar Fernandes; Afonso, José Augusto Bastos; Mendonça, Carla Lopes de; Zache, Eduardo; Silva, Thailan Arlindo da; Coutinho, Luiz Teles; Souza, Maria Isabel; Arenales, Alexandre.
Afiliação
  • Beserra, Lucas Alencar Fernandes; Universidade Federal Rural de Pernambuco. Garanhuns. BR
  • Afonso, José Augusto Bastos; Universidade Federal Rural de Pernambuco. Garanhuns. BR
  • Mendonça, Carla Lopes de; Universidade Federal Rural de Pernambuco. Garanhuns. BR
  • Zache, Eduardo; Universidade Federal Rural de Pernambuco. Garanhuns. BR
  • Silva, Thailan Arlindo da; Universidade Federal Rural de Pernambuco. Garanhuns. BR
  • Coutinho, Luiz Teles; Universidade Federal Rural de Pernambuco. Garanhuns. BR
  • Souza, Maria Isabel; Universidade Federal Rural de Pernambuco. Garanhuns. BR
  • Arenales, Alexandre; Universidade Federal Rural de Pernambuco. Garanhuns. BR
Braz. j. vet. pathol ; 15(3): 173-175, nov. 2022. tab, ilus
Article em En | VETINDEX | ID: biblio-1417462
Biblioteca responsável: BR68.1
ABSTRACT
We describe here hematological and biochemical findings in a cow with metastatic cholangiocarcinoma. On physical examination, apathy with congested mucous membranes, tachycardia and enlarged abdomen; hypoperistalsis in rumen, abomasum and intestines. In hematological examination, icteric plasma with leukocytosis by neutrophilia with regenerative left shift and inversion of the proportion between lymphocytes and segmented neutrophils, and hypofibrinemia. In serum biochemistry hyperproteinemia, hypoalbuminemia, hyperglobulinemia, low albumin/globulin ratio and high levels of aspartate aminotransferase, gamma-glutamyltransferase. The cow died and in necropsy was observed a severe and diffuse increase in volume predominantly on the hepatic right lobe and moderate increase of volume in mesenteric lymph nodes. Which was diagnosed microscopically as a cholangiocarcinoma, characterized by arrangements in irregular and coalescent ducts. In conclusion, cholangiocarcinoma may cause important hematological and biochemical changes in cattle.(AU)
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Texto completo: 1 Base de dados: VETINDEX Idioma: En Revista: Braz. j. vet. pathol Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: VETINDEX Idioma: En Revista: Braz. j. vet. pathol Ano de publicação: 2022 Tipo de documento: Article