Serum biochemistry in dogs infected with Ehrlichia canis, Anaplasma platys and Leishmania sp / Bioquímica sérica de cães infectados por Ehrlichia canis, Anaplasma platys e Leishmania sp

ABSTRACT

Background: Hemoparasitoses have major importance in clinical diseases of small animals for infections are highly prevalent, easily transmitted and difficult to control. Clinical signs are nonspecific, but laboratory abnormalities are frequent, especially changes in serum biochemistry. In veterinary medicine, laboratorial findings may favor the diagnosis of hemoparasitoses and improve the quality of treatment given to these patients. The present study aimed at evaluating changes in serum biochemistry in dogs with molecular diagnosis of hemoparasites (Ehrlichia canis, Anaplasma platys and Leishmania sp.).Materials, Methods & Results: Molecular diagnosis for Ehrlichia canis, Anaplasma platys and Leishmania sp. were obtained in 26 dogs. A complete serum biochemical profile was determined in biochemical analyzer COBAS Mira. Biochemical analyzes, using commercial kits from Synermed, included total and partial protein by colorimetric method, creatinine by the kinetic method, urea, alanine aminotransferase (ALT), aspartate aminotrasnferase (AST), gamma glutamyl transferase (GGT) and alkaline phosphatase by enzymatic method. Considering reference values for canine species, it was observed an increase in the average value for serum urea concentration in dogs with leishmaniasis. These dogs also presented higher globulin concentration, while presenting reduction in serum albumin...