Salmonella Heidelberg isolated from poultry shows a novel resistance profile

ABSTRACT

Background: The development of antimicrobial resistance in bacteria is a serious public health issue worldwide. Salmonella spp. is considered a leader cause of gastrointestinal disease in animals and humans, and poultry products have been reported as an important reservoir of the bacterium. S. Heidelberg became lately one of the most prevalent serovars found in several countries. However, hardly any information is available about the epidemiology and the resistance profile of it. Therefore, the objective of this study was to determine the antibiotic resistance profile of S. Heidelberg (SH) and to compare to S. Enteritidis (SE) and S. Typhimurium (ST) isolated from the Southern part of Brazil. Materials, Methods & Results: A total of 162 Salmonella isolates of poultry origin serotyped as SH (54), SE (54), and ST (54) were submitted to the disk-diffusion test with disks containing 10 antibiotics of 7 different classes, routinely used in veterinary and human medicine such as enrofloxacin, ciprofloxacin, norfloxacin, gentamicin, ceftiofur, ceftriaxone, nalidixic acid, tetracycline, sulfamethoxazole-trimethoprim, and chloramphenicol. In addition, the Multi-drug Resistance Pattern (MDRP) and the Multiple-Drug Resistance Index (MDRI) were determined. The Chi-square (2 ) test with 1% of significance level was used to statistically evaluate the results. All isolates were [...]