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Acta sci. vet. (Impr.); 50(suppl.1): Pub.767-4 jan. 2022. ilus

Artigo em Inglês | VETINDEX | ID: biblio-1458575

Resumo

Background: Hemangiosarcoma (HSA) is a malignant neoplasm arising from the endothelial cells of blood vessels. It has fast growth, and severe local infiltration and metastasis power, in addition to risk of hemorrhage due to the fragility of its vessels. HSA develops in dogs aged 8 to 13 years but can affect younger animals too. Ocular involvement in HSA is rare, but when identified, the third eyelid and bulbar conjunctiva close to the limbus are the most affected sites by this neoplasm. This study aimed to report the clinicopathological aspects of a case of HSA in the third eyelid of an American Pit Bull Terrier breed. Case: A 10-year-old male American Pit Bull Terrier with a history of a red hemorrhagic mass on the third eyelid of the left eye was examined at a veterinary clinic. On physical examination, the animal showed signs of ocular discomfort and bleeding. On ophthalmologic examination, a raised red mass, approximately 2 cm in diameter, was identified on the anterior surface of the third eyelid. The mass was surgically excised. The excised tissue fragment was fixed in 10% buffered formalin solution for 24 h and sent for histopathological examination. Macroscopically, the fragment was irregular, soft, and brownish and measured 2.0 × 1.0 × 0.5 cm. Histologically, proliferation of non-delimited and non-encapsulated atypical endothelial cells, which were organized in vascular arrangements forming small lakes filled with red blood cells, was observed. The cells exhibited elongated and basophilic cytoplasm, oval nuclei with coarse chromatin, and evident nucleoli. Moderate anisocytosis and anisocariosis were observed, with no mitotic figures. Epithelial hyperplasia with mild mixed inflammatory infiltrate was noted. Surgical margins were compromised. Sections of neoplastic tissue were processed...

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