Biopharmaceuticals from microorganisms: from production to purification
Braz. j. microbiol
; 472016.
Article
em En
|
LILACS-Express
| LILACS, VETINDEX
| ID: biblio-1469623
Biblioteca responsável:
BR68.1
ABSTRACT
ABSTRACT The use of biopharmaceuticals dates from the 19th century and within 5-10 years, up to 50% of all drugs in development will be biopharmaceuticals. In the 1980s, the biopharmaceutical industry experienced a significant growth in the production and approval of recombinant proteins such as interferons (IFN , , and ) and growth hormones. The production of biopharmaceuticals, known as bioprocess, involves a wide range of techniques. In this review, we discuss the technology involved in the bioprocess and describe the available strategies and main advances in microbial fermentation and purification process to obtain biopharmaceuticals.
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1
Base de dados:
LILACS
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VETINDEX
Idioma:
En
Revista:
Braz. j. microbiol
Ano de publicação:
2016
Tipo de documento:
Article