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Effect of platelet rich fibrin and beta tricalcium phosphate on bone healing. A histological study in pigs

Yilmaz, Dincer; Dogan, Necdet; Ozkan, Aydin; Sencimen, Metin; Ora, Baris Eren; Mutlu, Ibrahim.
Acta cir. bras.; 29(1): 59-65, 01/2014. tab, graf
Artigo em Inglês | VETINDEX | ID: vti-10197


To investigate the effect of platelet rich fibrin (PRF) and beta tricalcium phosphate (β-TCP), alone or in combination, on bone regeneration in pig tibial defects. METHODS: Four standardized defects were prepared in both tibias of three adult male pigs. The first defect was left unfilled as a control; the others were grafted with either PRF, β-TCP or PRF mixed with β-TCP. All animals were sacrificed on the 12th postoperative week and the tibial bones were removed, histologic sections were prepared and the experimental sites were examined microscopically and stereologically. RESULTS: Histologic and stereologic examination revealed more new bone formation in the defects filled with PRF mixed β-TCP than in the defects grafted with either β-TCP or PRF alone. CONCLUSION: The platelet rich fibrin and beta tricalcium phosphate combination effectively induces new bone formation.(AU)
Biblioteca responsável: BR1.1
Localização: BR68.1