Effect of platelet rich fibrin and beta tricalcium phosphate on bone healing. A histological study in pigs
Acta cir. bras.
; 29(1): 59-65, 01/2014. tab, graf
Article
em En
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ABSTRACT
To investigate the effect of platelet rich fibrin (PRF) and beta tricalcium phosphate (β-TCP), alone or in combination, on bone regeneration in pig tibial defects. METHODS:
Four standardized defects were prepared in both tibias of three adult male pigs. The first defect was left unfilled as a control; the others were grafted with either PRF, β-TCP or PRF mixed with β-TCP. All animals were sacrificed on the 12th postoperative week and the tibial bones were removed, histologic sections were prepared and the experimental sites were examined microscopically and stereologically.RESULTS:
Histologic and stereologic examination revealed more new bone formation in the defects filled with PRF mixed β-TCP than in the defects grafted with either β-TCP or PRF alone.CONCLUSION:
The platelet rich fibrin and beta tricalcium phosphate combination effectively induces new bone formation.(AU)Palavras-chave
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VETINDEX
Idioma:
En
Revista:
Acta cir. bras.
Ano de publicação:
2014
Tipo de documento:
Article