Urethral dysfunction due to alloxan-induced diabetes. Urodynamic evaluation and action of sildenafil citrate
Pegorare, Ana Beatriz Gomes de Souza; Gonçalves, Marco Antonio; Oliveira, Alessandra Martiniano de; Rodrigues Junior, Antonio Antunes; Tucci Jr, Silvio; Suaid, Haylton Jorge.
Acta cir. bras.;
29(4): 274-279, 04/2014. tab, graf
Artigo
em Inglês
| VETINDEX
| ID: vti-10228
Resumo
To evaluate the effect of diabetes mellitus and of sildenafil citrate on female urethral function. Twenty nine female rats were divided into four groups: G1 - (n=9), normal rats; G2 - (n=6), normal rats treated with sildenafil citrate; G3 - (n=9) rats with alloxan-induced diabetes; G4 - (n=5) rats with alloxan-induced diabetes treated with sildenafil citrate. Under anesthesia, urodynamic evaluation was performed by cystometry and urethral pressure simultaneously. A significant increase in urethral pressure was observed during micturition. Sildenafil citrate can partially reduced urethral pressure in diabetic female rats.(AU)
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BR1.1
Localização: BR68.1
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