Immunohistochemical detection of viral etiopathogenesis in lambs and goat kids with neonatal diarrhea
Acta sci. vet. (Impr.)
; 46: 1-8, 2018. ilus
Article
em En
| VETINDEX
| ID: biblio-1457863
Biblioteca responsável:
BR68.1
Localização: BR68.1
ABSTRACT
Background:
Neonatal enteritis is an important disease that causes deaths of animals before 3 weeks of age, and results in significant economic losses. Viral agents can predispose the young animals to secondary infections in the gastrointestinal tract, especially in lambs and goat kids younger than 21 days. Although the neonatal diarrhea is common in calves, there is still little knowledge about pathology, pathogenesis and immunohistochemical localization of viral agents that cause neonatal enteritis in lambs and goat kids. In this study, we carried out investigations with the aim of detecting adenovirus, rotavirus, coronavirus and herpes virus in the guts of goat kids and lambs with viral enteritis.Materials, Methods &Results:
Adenovirus, rotavirus, coronavirus and herpes virus antisera were applied to paraffinembedded intestinal tissue from neonatal lambs and kids that had died from enteritis. In addition, viral agents in the gut cells were detected and evaluated by electron microscopy. The study material consisted of 15 lambs and 15 goat kids that were presented for diagnosis. Viral agents were detected by immunohistochemically in 20 out of 30 animals. Rotavirus was diagnosed in 10 animals, adenovirus in five, herpes virus in three and coronavirus in two animals; and these results were supported by the electron microscopy. This study showed that viral agents play an important role in neonatal enteritis in lambs and kids.Discussion:
Bacteria, viruses and protozoa may have a role in the etiology of neonatal enteritis and identifying the etiological agents is not always possible without laboratory studies. In addition, the immune system of the animal and environmental factors are important factors for to occurrence of the disease.[...]Palavras-chave
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Base de dados:
VETINDEX
Idioma:
En
Revista:
Acta sci. vet. (Impr.)
/
Acta sci. vet. (Online)
Ano de publicação:
2018
Tipo de documento:
Article
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Project document