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Exostose cartilaginosa múltipla em um canino pediátrico / Multiple cartilaginous exostoses in a pediatric dog

Bezerra, José Artur Brilhante; Rodrigues, Ramon Tadeu Galvão Alves; Antunes, João Marcelo Azevedo de Paula; Oliveira, Luanda Pâmela César de; Moura, Carlos Eduardo Bezerra de; Filgueira, Kilder Dantas.
Acta sci. vet. (Online); 47(suppl.1): Pub. 390, May 30, 2019. ilus
Artigo em Português | VETINDEX | ID: vti-19823

Resumo

Background: Multiple cartilaginous exostosis (MCE) is a rare neoplastic disease in dogs that is characterized by the presence of osteochondromas in multiple bones. MCE is a disorder of development during growth and maturation, the realetiology of which has yet to be elucidated, but is believed to have a genetic basis. Usually affected animals have a historyof a palpable mass on the bone surface, causing anatomical deformities and compression of adjacent structures. SinceMCE is a rare neoplastic disease in dogs it may be difficult to recognize in the clinic. The aim of this study was to reporta case of MCE in a pediatric dog.Case: A female 4-month-old Rottweiler dog with a history of bone neoformation on the left hind limb, anorexia, weightloss, and difficulty walking received clinical care. The disease had its initial onset 2 months prior. At physical examination, the animal showed paresis of the hind limbs and a bony tumor on the lateral part of the left tibia. A complete bloodcell count and serum biochemical profile were obtained. The only abnormality diagnosed was hyperproteinemia due tohyperglobulinemia. Other diagnostic tests were not authorized and the animal was euthanized. At the necropsy, an intrathoracic neoformation was observed from the sixth to the eighth rib on the right antimer. Some tumors were also observedon the fourth lumbar vertebra and between the first and the second sacral vertebra, and a left tibial tumor, which had beenobserved at physical examination. The sagittal section of the spine revealed the presence of extradural compression of thespinal cord due to vertebral proliferations with compression of the nerve roots. All of the proliferations had macroscopicsimilarities, being firm, sessile, irregular, and with complete adherence to deep planes. Tumor samples were submitted tohistopathological analysis and the tissue morphology was compatible with osteochondroma...(AU)
Biblioteca responsável: BR68.1