Experimental models of scald burns. A scope review
Menegat, Taís Amadio; Oliveira, Andrea Fernandes de; Majewski, Michelle Gioia Coiado; Blanes, Leila; Juliano, Yara; Novo, Neil Ferreira; Ferreira, Lydia Masako.
Acta cir. bras.;
34(10): e201901007, 2019. ilus, tab
Artigo
em Inglês
| VETINDEX
| ID: vti-24036
Resumo
Purpose:To conduct a scope review of the experimental model described by Walker and Mason, by identifying and analyzing the details of the method.Methods:The authors searched Pubmed-Medline, Cochrane-Bireme and PEDro databases for articles published between January 2016 and December 2018, using the following search queries: burns, burn injuries, models animal, and animal experimentation. All articles whose authors used Walker and Mason's model - with or without changes to the method in Wistar rats - were included in this study.Results:The search identified 45 mentions of Walker and Mason's model; however, after reading each summary, 20 were excluded (of which 5 due to duplicity). The inconsistencies observed after the scope review were: water temperature, length of time of exposure of the experimental model's skin to water, extent of the burnt area, and the description of the thickness/depth of the injury.Conclusions:Reproducibility of a scientific method is the basis to prove the veracity of the observed results. Thus, it is necessary to have a greater number of publications that adopt a reproducible scientific method, for this review found inconsistencies in the description of Walker and Mason's model.(AU)
Biblioteca responsável:
BR68.1
Localização: BR68.1
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