Estudo histopatológico dos órgãos reprodutivos de ratos tratados com extrato etanólico de Simarouba versicolor em ensaio de toxicidade sub-crônica / Histopathological study of the reproductive organs of rats treated with ethanol extract of Simarouba versicolor in test sub-chronic toxicity
Cavalcante, Ykro Talvanis Duarte; Cunha, Ana Paula Gomes Pereira; Fontenele, Rayssa Dourado; Fernandes, Mayara De Lima Moreno; Mineiro, Ana Lys Bezerra Barradas; Fernandes, Rozeverter Moreno; Fernandes, Maria Zenaide De Lima Chagas Moreno.
R. bras. Reprod. Anim.;
40(4): 611-612, Out-Dez. 2016. tab
Artigo
em Português
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| ID: vti-24289
Resumo
The aim of this study was to evaluate the reproductive organs on the effect of Simarouba versicolorethanol extract (EEOH-Sv) at a dose of 10mg / kg administered for 60 days / VO. The testes, epididymis,prostate and seminal vesicles were sectioned and placed in vials Boan solution for 24 hours and then preservedin alcohol at 70%. Histopathology of organs were dehydrated in xylol, impregnated and embedded in paraffin.Subsequently cut in the microtome at a thickness of 3 m and subjected to hematoxylin-eosin. The results of thehistopathology of the testis was observed that the EEOH-Sv caused concretions in 100% of animals evaluatedand 20% of the animals showed sharp associated with degeneration of the seminiferous tubules. In theepididymis was observed in 40% epithelial thickening, and there was 100% of benign prostatic hypertrophyassociated in 20% of animals inflammatory infiltrate. Thus, it is concluded that-Sv EEOH was toxic to thisorgans except the seminal vesicle.(AU)
Biblioteca responsável:
BR68.1
Localização: BR68.1
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