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Piometra em cadela possivelmente causada pelo uso simultâneo de levonorgestrel e cipionato de estradiol / Pyometra in a bitch possibly caused by simultaneous administration of levonorgestrel and estradiol cypionate

Silva, Filipi Alexandre do Nascimento; Franciscato, Caroline Sestito; Sala, Pollyana Linhares; Sá, Thaís Camaso de; Trentim, Mayara da Silva; Zaniolo, Melissa Marchi; Costa, Icaro Mateus Cosmo de Moura; Quessada, Ana Maria.
Acta sci. vet. (Online); 47(suppl.1): Pub. 428, Oct. 11, 2019. ilus
Artigo em Português | VETINDEX | ID: vti-25729


Background: Toxicological events in animals may be accidental or intentional and could occur in the home environment.These events could involve different agents such as pesticides, rodenticides, medicines, foods, and plants. Indiscriminateuse of medication in pets by their owners is common. Self-medication of animals with drugs for human use can cause irreversible damage to their health. The emergency contraceptive pill (morning-after pill), comprising concentrated hormonalcompounds, is sold freely in Brazil. The objective of this article was to report a case of pyometra in a bitch possibly causedby simultaneous administration of human emergency contraceptive pill along with a veterinary contraceptive medication.Case: A 6-year-old bitch was referred to a Veterinary Medical Teaching Hospital for abdominal enlargement. Accordingto the guardian, during estrus (30 days before the consultation) the female dog was covered. After intercourse, the owneradministered a human emergency contraceptive pill (morning-after pill - Levonorgestrel) and a veterinary contraceptive(Estradiol Cypionate). Physical examination revealed severe dehydration (10%) and high temperature, besides the abdominalenlargement. The hemogram revealed leukocytosis with a left shift, characteristic of infection. After clinical examination,closed pyometra was suspected, and later confirmed by ultrasonography. Due to the poor clinical condition, fluid therapywas performed, and a systemic antibiotic was administered. After stabilization, the patient underwent ovariohysterectomy.In the postoperative period, the fluid therapy was continued, and antibiotic and anti-inflammatory drugs were administered.Two days after surgery, the patient was discharged for home recovery.Discussion: Most cases of drug poisoning in animals involve female dogs, similar to the patient in this report. There isno theory elucidating the same, but the rate of incidence in female dogs has been reported to be higher...(AU)
Biblioteca responsável: BR68.1
Localização: BR68.1