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Whole cells in enantioselective reduction of benzyl acetoacetate

Ribeiro, Joyce Benzaquem; Ramos, Aline de Souza; Lopes, Raquel de Oliveira; Silva, Gabriela Veloso Vieira da; Souza, Rodrigo Octavio Mendonça Alves de.
Braz. J. Microbiol.; 45(3): 929-932, July-Sept. 2014. ilus, tab
Artigo em Inglês | VETINDEX | ID: vti-29127

Resumo

The β-ketoester benzyl acetoacetate was enantioselectively reduced to benzyl (S)-3-hydroxybutanoate by seven microorganism species. The best result using free cells was obtained with the yeast Hansenula sp., which furnished 97% ee and 85% of conversion within 24 h. After immobilization in calcium alginate spheres, K.marxianus showed to be more stable after 2 cycles of reaction.
Biblioteca responsável: BR68.1
Localização: BR68.1