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Histological evaluation of the effect of low-frequency electric stimulation on healing Achilles tendons in rats

Casagrande, Sharbo Martins; Biondo-Simões, Maria de Lourdes Pessole; Ioshii, Sergio; Robes, Rogério Ribeiro; Biondo-Simões, Rachel; Boeno, Bruno Russiano de Oliveira.
Acta cir. bras.; 36(1): e360103, 2021. ilus, graf, tab
Artigo em Inglês | VETINDEX | ID: vti-30536


Purpose: Histologically evaluate the effects of low frequency electrical stimulation in the treatment of Achilles tendon injuries in rats. Methods: Thirty-four rats underwent Achilles tendon tenotomy and tenorrhaphy. They were randomly allocated in two groups. Half of the sample constituted the experiment group, whose lesions were stimulated with 2 Hz, nonpolarized current and 1 mA, for 14 days. The other animals formed the control group. They were evaluated at 2, 4 and 6 weeks. The histological study was carried out, the collagen density and the wound maturity index were measured. Results: The healing score was higher in the group stimulated at the 6th week (p = 0.018). The density collagen 1 was higher in the group treated at the three times (p = 0.004) and that collagen 3 was higher in the group treated at 6 weeks (p = 0.004). Together, collagen 1 and 3 were higher in the group stimulated at 4 and 6 weeks (p = 0.009, p = 0.004). The maturity index was higher in this group at the three moments (p = 0.017 p = 0.004 and p = 0.009). Conclusion: Low frequency electric stimulation improved healing and increased the quantity of collagen.(AU)
Biblioteca responsável: BR68.1
Localização: BR68.1