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Comparação entre o efeito do Piroxicam e do Trocoxil, no controle da inflamação em neoplasias mamárias de cadelas utilizando a termografia / Thermographic comparison between piroxicam and trocoxil anti inflammatory effects in canine mammary tumors

GREGHI, Julia Rodrigues; FERNANDES, Maíra Planzo; SCHINITZER, Josiana de Fátima; YOKOMIZO, Débora Nakayama; DI SANTIS, Giovana Wingeter; MARTINS, Maria Isabel Mello.
Ci. Anim.; 30(04, Supl. 2): 239-242, 2020.
Artigo em Português | VETINDEX | ID: vti-32094

Resumo

Malignant mammary tumors are most prevalent neoplasms in bitches. Currently, it is known the influence of several factors and biological markers involved in tumors development, such as cyclooxygenase-2. Use of non-steroidal anti-inflammatory drugs appears as a promising adjuvant treatment. The aim of this study was to evaluate and to compare the effectiveness of piroxicam and Trocoxil® (mavacoxib) in reduce the peritumoral temperature. At random, it was selected 16 middle-aged bitches presenting mammary tumor according the routine of the Veterinary Hospital. On day 0, after clinical examination and thermography of both mammary chains, piroxicam was prescribed to group 1 (n=12) (0.3mg/kg, VO, SID, 10 days) and to group 2 (n=4) was prescribed Trocoxil® (2mg/kg, VO, single dose). After 10 days, the animals returned for further evaluation and the second thermography. The images were analyzed, tabulated and submitted to statistical analysis by the SigmaPlot® program in a simple t-test, considering p<0.05. The results indicated that Trocoxil® showed a better ability to reduce peritumoral temperature than piroxicam after 10 days of treatment (p=0.041), suggesting this drug with better efficiency in the adjuvant treatment of mammary neoplasms in bitches.(AU)
Biblioteca responsável: BR68.1
Localização: BR68.1