Avaliação da concentração do lactato desidrogenase em cadelas portadoras de neoplasias mamárias / Evaluation of the concentration of lactate dehydrogenase in bitches with mammary gland tumor
PINHEIRO, Breno Queiroz; BARBOSA, Hélida Tainan Silva; MAGALHÃES, Francisco Felipe de; SOUZA, Carmen Vládia Soares de; ALVES, Francisco Wesley da Silva; SILVA, Isaac Neto Góes da; SILVA, Lúcia Daniel Machado da.
Ci. Anim.;
30(04, Supl. 2): 219-223, 2020. graf, tab
Artigo
em Português
| VETINDEX
| ID: vti-32098
Resumo
The increase in lactate dehydrogenase (LDH) activity is associated with hypoxia due to the rapid proliferation of cancer cells and high metabolic demands. Few studies have evaluated the LDH concentration in canine mammary tumor (CMT). Thus, the objective of this work was to evaluate serum LDH concentrations in CMT and its association with prognostic factors. Thirty bitches participated in the work and were divided equally into two groups, with and without CMT. The average concentration of LDH was significantly higher in CMT (424.9±244.4U / L) compared to the control group (299.0±170.3 U / L) and its values were positively correlated with inflammation and / or macroscopic ulceration (r=0.6), tumor size (r=0.5), histopathological grade (r=0.6), metastatic lymph node (r=0.7) and clinical stage (r=0.5).(AU)
Biblioteca responsável:
BR68.1
Localização: BR68.1
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