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Association of porcine circovirus infection with mycotoxicosis: a case report
Acta Vet. bras. ; 16(1)2022.
Article em En | VETINDEX | ID: vti-32952
Biblioteca responsável: BR68.1
ABSTRACT
Circovirus is widespread in pig farming, and mainly affects piglets increasing morbidity and mortality rates, being vaccination the most effective strategy to control one. However, for an effective vaccine response, certain factors must be considered, such as the adoption of good practices during the conservation and handling of vaccines, environmental challenges, nutritional and health status of the animals, and presence of immunosuppressive agents, such as mycotoxins, in the feed. Here, we describe a circovirus outbreak associated with mycotoxin immunosuppression that occurred in the piglets during the nursery phase at a commercial farm, which initiated with a sudden increase in the mortality of vaccinated piglets. Blood samples were collected and analyzed using RT-PCR, while the feed was subjected to mycotoxicological analysis. RT-PCR analysis revealed the presence of porcine circovirus type 2 (PCV-2) in the blood serum samples, thereby confirming the circovirus outbreak. The feed analysis revealed elevated levels of mycotoxins (deoxynivalenol, aflatoxins, and fumonisins), which were above the levels tolerated by the piglets during the nursery phase. Therefore, the contaminated feed was discarded, and a new ration was made available. Concurrently, the vaccination program was amended to normalize the mortality rate. The presence of mycotoxins in the feed could be the predispo
Texto completo: 1 Base de dados: VETINDEX Idioma: En Revista: Acta Vet. bras. Ano de publicação: 2022 Tipo de documento: Article
Texto completo: 1 Base de dados: VETINDEX Idioma: En Revista: Acta Vet. bras. Ano de publicação: 2022 Tipo de documento: Article