Effect of Curcuma zedoaria crude extract against tumor progression and immunomodulation
Carvalho, F. R; Vassão, R. C; Nicoletti, M. A; Maria, D. A.
J. Venom. Anim. Toxins incl. Trop. Dis.;
16(2): 324-341, 2010. ilus, graf
Artigo
em Inglês
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| ID: vti-4278
Resumo
The aim of the present work was to study the effect of the crude extract of Curcuma zedoaria on peripheral blood cells and tumor progression in C57Bl/6J mice injected with B16F10 murine melanoma cells. The intraperitoneal therapy showed a significant increase in total white and red blood cell counts, a decrease in peritoneal cell number and tumor volume reduction, whereas the oral administration revealed a noteworthy augmentation only in total leukocyte count. These results contribute to evaluate the importance of alternative treatments that employ phytotherapic compounds against tumor progression and its possible immunomodulation.(AU)
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