Synergic interaction of aromatic compounds anethol and carvone against nematode Haemonchus / Interação sinérgica dos compostos aromáticos anetol e carvona em nematoide Haemonchus contortus de cepa resistente
Morita Katiki, Luciana; Moraes Evangelista Barbieri, Andiara; Ceneviva Fornazari, Bruno; Canonenco Araújo, Rafael; Louvandini, Helder; Lopes Dias da Costa, Ricardo; Sartori Bueno, Mauro; José Veríssimo, Cecília.
B. Indústr. Anim.;
71: 63-63, 2014.
Artigo
em Inglês
| VETINDEX
| ID: vti-468061
Resumo
The aim of this work was to evaluate the aromatic compounds Anethole and Carvone and its synergic anthelmintic interactions against sheep gastrointestinal nematode Haemonchus contortus multi resistant strain. Anthelmintic resistance has been a hindrance in animal production causing economic losses and consequence of the repetitive use of those ineffective chemicals it is usual to found contamination on meat, milk and environment. New sources of anthelmintic compounds have been investigated. Plant extracts and natural compounds have demonstrated themselves as promising candidates. Eggs were collected from feces of sheep infected with H.contortus. A hundred eggs were exposed to solutions of Anethole and Carvone and half and half Anethole and Carvone diluted in water and solvent Tween 80 in concentrations ranging from 2.08 mg/mL to 0.007mg/mL (decreasing three fold concentrations) with six replicates using a 24 well plate to perform tests. Eggs were incubated for 24 h at 27C and the count of eggs hatched was done using an inverted microscope. Data were analyzed by SAS Probit to estimate LC50 with independent variables (dose) transformed by natural logarithm (log dose). The LC50 (fiducial limits) in mg/mL of Anethole was 0.070 (0.068-0.076), Carvone was 0.085 (0.081-0.088) and the synergic interaction of Anethole+ Carvone was 0.013 (0.012-0.014), according to Table 1. Gas chromatoO artigo não apresenta resumo em português.
Biblioteca responsável:
BR68.1
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