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Comparison of the effects of epidurally administered bupivacaine and levobupivacaine in conscious dogs / Comparison of the effects of epidurally administered bupivacaine and levobupivacaine in conscious dogs

Korkmaz, Musa; Kadir Saritas, Zulfikar.
Acta Sci. vet.; 41: 01-09, 2013.
Artigo em Inglês | VETINDEX-Express | ID: vti-480132

Resumo

Background: The epidural administration of local anaesthetic agents was advocated for use in any surgical procedure caudal to the diaphragm in dogs but was superior for procedures involving the pelvis, hind limbs, and perineal area. The aim of this study was to determine anaesthetic profiles of bupivacaine (BP) and levobupivacaine (LP) in epidural anaesthesia (EA) and to compare their effects on hemodynamics, blood gases, hematological and biochemical parameters in conscious dogs. Materials, Methods & Results: In this study, a total of 20 adult male dogs from different breeds referred to our clinics for castration purposes were used and allocated into two groups; 10 dogs in BP and 10 dogs in LP groups. In this study, each animal received a 0.5% of either BP or LP epidurally, (a fixed total volume of 0.2 mL/kg) followed by 0.3 mL saline solution to flush the dead space in the valve and catheter. Throughout the epidural anaesthesia, heart rate, respiratory rate, systolic and diastolic blood pressure, mean arterial blood pressure, and body temperature were monitored. Similarly, during the study, haematological measurements at 0th, 2nd, 4th, 6th, and 8th h and biochemical measurements at 0th, 2nd, 4th, 6th, 8th and 24th h in blood samples were examined. Simultaneously, blood gases, and Na+ and K+ levels in arterial blood samples were measured at 0th, 30th, 60th, 120th and 240th
Background: The epidural administration of local anaesthetic agents was advocated for use in any surgical procedure caudal to the diaphragm in dogs but was superior for procedures involving the pelvis, hind limbs, and perineal area. The aim of this study was to determine anaesthetic profiles of bupivacaine (BP) and levobupivacaine (LP) in epidural anaesthesia (EA) and to compare their effects on hemodynamics, blood gases, hematological and biochemical parameters in conscious dogs. Materials, Methods & Results: In this study, a total of 20 adult male dogs from different breeds referred to our clinics for castration purposes were used and allocated into two groups; 10 dogs in BP and 10 dogs in LP groups. In this study, each animal received a 0.5% of either BP or LP epidurally, (a fixed total volume of 0.2 mL/kg) followed by 0.3 mL saline solution to flush the dead space in the valve and catheter. Throughout the epidural anaesthesia, heart rate, respiratory rate, systolic and diastolic blood pressure, mean arterial blood pressure, and body temperature were monitored. Similarly, during the study, haematological measurements at 0th, 2nd, 4th, 6th, and 8th h and biochemical measurements at 0th, 2nd, 4th, 6th, 8th and 24th h in blood samples were examined. Simultaneously, blood gases, and Na+ and K+ levels in arterial blood samples were measured at 0th, 30th, 60th, 120th and 240th
Biblioteca responsável: BR68.1