Atividade inibitória do óleo essencial de orégano em fungos de importância médica e veterinária / Inhibitory activity of origanum essential oil against important fungus in veterinary
Cleff, M. B; Meinerz, A. R; Faria, R. O; Xavier, M. O; Santin, R; Nascente, P. S; Rodrigues, M. R; Meireles, M. C. A.
Arq. bras. med. vet. zootec;
62(5): 1291-1294, out. 2010. graf, tab
Artigo
em Português
| VETINDEX
| ID: vti-6025
Resumo
The in vitro activity of Origanum vulgare essential oil against fungal isolates was evaluated. A total of 27 clinical isolates were used, including: C. albicans, S. schenckii, M. pachydermatis, Aspergillus flavus, and A. fumigatus. Microdilution in broth technique (NCCLS M27-A2 and M-38) was used and susceptibility was expressed as Minimum Inhibitory Concentration (MIC). Essential oil was obtained by hydrodistillation in Clevenger and analyzed by gas chromatography, showing the presence of 4-terpineol, alpha-terpineol, 4-terpinene, thymol and carvacrol, as the main compounds. Origanum oil MIC for C. albicans varied from 125 to 500mL/mL; for S. schenckii, from 250 to 500mL/mL; for M. pachydermatis, from 15 to 30mL/mL; and for Aspergillus, from 30 to 60mL/mL. Isolates sensitivity showed to the origanum oil stimulates the accomplishment of new studies, including in vivo tests, contributing to the search of alternative treatments to mycosis.(AU)
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