Effects of leptin and adinopectin on cardiovascular, respiratory and haematological systems of healthy dogs
Fernandes de Queiroz, Genilson; Barbalho Macêdo, Luã; Simea de Andrade Chaves, Hildita; Veras de Paula, Valéria; Maria Matera, Julia; Menezes do Vale, André; Modesto Junior, João.
Acta Vet. bras.;
11(3): 145-149, 2017.
Artigo
em Inglês
| VETINDEX
| ID: vti-722235
Resumo
Adipocytokines are substances produced by adipocytes responsible for the regulation of several physiological processes. Among those substances, leptin and adiponectin have been intensively investigated because of their possible effects on metabolism, reproduction, hematopoiesis and cardiovascular system. The current study aimed to assess the effects of adipocytokines, leptin and adiponectin on cardiac and respiratory functions, as well as on the hematological parameters of healthy female dogs of different breeds. Parameters of rectal temperature, diastolic blood pressure, systolic blood pressure, mean arterial pressure, pulse, heart rate and respiratory rate were evaluated in fifty two healthy female dogs. Blood samples were collected for complete blood count and plasma leptin and adiponectin measurement via ELISA technique. There was no difference in circulating levels of adipocytokines among the different breeds (p 0,05). Negative correlation between leptin and mean corpuscular hemoglobin concentration was found, while it was positive regarding systolic blood pressure, heart rate and breathing. Adiponectin was positively correlated with red blood cells and platelets and negatively with heart rate, respiratory rate, diastolic blood pressure and pulse. Adipocytokines, leptin and adiponectin, exert regulatory effects on cardiorespiratory function and hematopoiesis in healthy f
Biblioteca responsável:
BR68.1
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