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Suíno como modelo experimental na pesquisa biomédica: valores fisiológicos normais

Cabral Gianotti, Giordano; Krüger Beheregaray, Wanessa; Passos Bianchi, Simone; Santos Mombach, Verônica; Bonfim Carregaro, Adriano; Antonio Contesini, Emerson.
Acta Sci. vet.; 38(2): 133-137, 2010.
Artigo em Português | VETINDEX-Express | ID: vti-733370

Resumo

Background:   The use of animals in biomedical research is of great importance. It is fundamental for the development and improvement of new practices and technologies. The selection of the species must take into consideration the practicality of handling and the suitability for the experiment, and it must have low operational costs. Swine are important as an experimental model in several experiment areas, because the functionality of many of their organic systems is developed similarly as it is in humans. Swine are animals that become easily stressed. For that reason, their conditioning is necessary to allow the obtainment of data that is closer to normal parameters. This study aims at reporting the physiological values obtained from awake swine, under normal conditions and minimum stress. Materials, Methods & Results: The animals were maintained under ideal environmental conditions, and they were always handled and conditioned by the same persons. Twenty crossbred swine were evaluated, aged between 60 and 90 days and with a body mass ranging between 17 and 25 kg. The parameters considered were cardiac frequency (FC),  emoglobin oxygen saturation (pulse oxymetry SPO2), respiratory frequency (fR), end tidal carbon dioxide (ETCO2), systolic (PAM), diastolic (PAD) and mean (PAM) arterial pressure and arterial blood gas values pH, arterial pressure of CO2 (PACO2), arterial
Biblioteca responsável: BR68.1