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Chronic kidney failure following lancehead bite envenoming: a clinical report from the Amazon region

Pucca, Manuela B.; Franco, Michelle V. S.; Medeiros, Jilvando M.; Oliveira, Isadora S.; Ahmadi, Shirin; Cerni, Felipe A.; Zottich, Umberto; Bassoli, Bruna K.; Monteiro, Wuelton M.; Laustsen, Andreas H..
Artigo em Inglês | VETINDEX-Express | ID: vti-760230


Abstract Background: Snakebite envenoming can be a life-threatening condition, for which emergency care is essential. The Bothrops (lancehead) genus is responsible for most snakebite-related deaths and permanent loss of function in human victims in Latin America. Bothrops spp. venom is a complex mixture of different proteins that are known to cause local necrosis, coagulopathy, and acute kidney injury. However, the long-term effects of these viper envenomings have remained largely understudied. Case presentation: Here, we present a case report of a 46-years old female patient from Las Claritas, Venezuela, who was envenomed by a snake from the Bothrops genus. The patient was followed for a 10-year period, during which she presented oliguric renal failure, culminating in kidney failure 60 months after the envenoming. Conclusion: In Latin America, especially in Brazil, where there is a high prevalence of Bothrops envenoming, it may be relevant to establish long-term outpatient programs. This would reduce late adverse events, such as chronic kidney disease, and optimize public financial resources by avoiding hemodialysis and consequently kidney transplantation.
Biblioteca responsável: BR68.1