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OPHTHALMOLOGICAL AND NEUROLOGICAL MANIFESTATIONS OF A DOG WITH INTRACRANIAL ANAPLASTIC EPENDYMOMA. CASE REPORT
FERRAZ, C.; TORRES NETO, R.; ROMALDINI, A.; CIRIO, S. M.; DEL FAVA, C..
Afiliação
  • FERRAZ, C.; Instituto Qualittas.
  • TORRES NETO, R.; Laboratório VetMol.
  • ROMALDINI, A.; Hospital Veterinário Dr. Hato.
  • CIRIO, S. M.; Instituto Qualittas.
  • DEL FAVA, C.; Instituto Biológico.
Ars vet ; 37(3): 158-165, 2021.
Article em En | VETINDEX | ID: vti-764956
Biblioteca responsável: BR68.1
ABSTRACT
The objective is to report ependymoma associated with uveitis in a four-month-old male boxer crossbreed. The dog initially presented in both eyes conjunctival hyperemia, blepharospasm, projection of the nictitating membrane, and photophobia, characteristic of uveitis.Traumatic uveitis was rejected. Six days after onset of ophthalmic symptoms, vomiting, incoordination, and behavior changes occurred. Neurological symptoms and eyebrow contraction suggesting head pain and brain injury were investigated by computed tomography (CT) nine days after, when the dog showed spasms of the limbs and neck followed by respiratory arrest with reversal and stabilization. The scans revealed extensive amorphic neoformation in the diencephalon, midbrain, and within the right lateral ventricle, along with sinistral displacement of the cerebral sickle. The animal was euthanized, and necropsy of the head revealed hydrocephalus and an intracerebral tumor mass consistent with the CT imaging. Histopathological evaluation by hematoxylin and eosin staining revealed tissue alterations in several CNS segments, showing several pseudorosettes in the neuropil, mitosis, and a high degree of cell atypia, indicating ependymoma.Inflammatory, hemorrhagic, and necrotic tissue lesions were observed in the brainstem and cerebellum due to compression by tumor tissue and hydrocephalus. The neoplasia was phenotyped by Imm
Texto completo: 1 Base de dados: VETINDEX Idioma: En Revista: Ars vet Ano de publicação: 2021 Tipo de documento: Article
Texto completo: 1 Base de dados: VETINDEX Idioma: En Revista: Ars vet Ano de publicação: 2021 Tipo de documento: Article