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Immunohistochemistry of the uterine cervix of rats bearing the Walker 256 tumor treated with copaiba balsam
Botelho, Nara Macedo; Corrêa, Suelen Costa; Lobato, Rodolfo Costa; Teixeira, Renan Kleber Costa; Quaresma, Juarez Antônio Simões.
Afiliação
  • Botelho, Nara Macedo; Universidade do Estado do Pará. Departamento de Saúde Especializada. Pará. Brasil
  • Corrêa, Suelen Costa; Universidade do Estado do Pará. Departamento de Pediatria. Pará. Brasil
  • Lobato, Rodolfo Costa; Universidade do Estado do Pará. Departamento de Cirurgia. Pará. Brasil
  • Teixeira, Renan Kleber Costa; Universidade do Estado do Pará. Pará. Brasil
  • Quaresma, Juarez Antônio Simões; Universidade do Estado do Pará. Núcleo de Medicina Tropical. Laboratório de Imunopatologia. Pará. Brasil
Acta cir. bras. ; 28(3): 185-189, 2013. ilus, tab
Article em En | VETINDEX | ID: vti-8965
Biblioteca responsável: BR1.1
Localização: BR68.1
ABSTRACT

PURPOSE:

To investigate the immunohistochemistry of the uterine cervix of 20 Wistar rats (Rattus norvegicus) bearing the Walker 256 tumor, treated with copaiba oil (Copaifera officinalis).

METHODS:

The animals were grouped into four subgroups, with five rats each the GCT and GCopT received distilled water and topically copaiba, respectively, while the GCG and GCopG received distilled water and copaiba by gavage, respectively. The substances were administered for nine days. On the 12th day, after euthanasia, the tumor pieces were sent to the identification of T CD4+, T CD8+ and Natural Killer cells.

RESULTS:

It was found that the pattern of expression for specific markers of phenotypes of cells involved in tumor immune response was similar in all groups, regardless the administration way of copaiba oil (topical or gavage).

CONCLUSION:

Copaiba balsam, administered either topically or by gavage, did not alter the pattern of tumor immune response in rats bearing Walker 256 Tumor.(AU)
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Texto completo: 1 Base de dados: VETINDEX Idioma: En Revista: Acta cir. bras. Ano de publicação: 2013 Tipo de documento: Article

Texto completo: 1 Base de dados: VETINDEX Idioma: En Revista: Acta cir. bras. Ano de publicação: 2013 Tipo de documento: Article