Angiogenic factors and ovarian follicle development
Bruno, J B; Matos, M H T; Chaves, R N; Celestino, J J H; Saraiva, M V A; Lima-Verde, I B; Araújo, V R; Fiqueiredo, J R.
Anim. Reprod.;
6(2): 371-379, 2009.
Artigo
em Inglês
| VETINDEX
| ID: vti-9392
Resumo
Ovarian follicles require an adequate blood supply for oxygen, nutrients and hormones, in addition to eliminating CO2 and other metabolites. Acquisition of an adequate vascular supply is probably a limiting step in the selection and maturation of the dominant follicle. In this way, there is a progressive interest in the study of the growth factors involved in the angiogenic process. In addition, a better understanding about the mechanisms that regulate the expression and action of these factors could be a key point to increase the reproductive performance in females. Therefore, this review aims to summarize current data on the importance of the pro- and anti-angiogenic growth factors which regulate angiogenesis in ovarian follicle development.(AU)
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BR68.1
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