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Regulation of ovarian folliculogenesis by Kit Ligand and the c-Kit system in mammals
Celestino, J J H; Matos, M H T; Saraiva, M V A; Figueiredo, J R.
Afiliação
  • Celestino, J J H; Universidade Estadual do Ceará. Faculdade de Medicina Veterinária. Fortaleza. Brasil
  • Matos, M H T; Universidade Estadual do Ceará. Faculdade de Medicina Veterinária. Fortaleza. Brasil
  • Saraiva, M V A; Universidade Estadual do Ceará. Faculdade de Medicina Veterinária. Fortaleza. Brasil
  • Figueiredo, J R; Universidade Estadual do Ceará. Faculdade de Medicina Veterinária. Fortaleza. Brasil
Anim. Reprod. ; 6(3): 431-439, 2009. ilus
Article em En | VETINDEX | ID: vti-9491
Biblioteca responsável: BR68.1
Localização: BR68.1
ABSTRACT
The system comprised of Kit Ligand (KL) and its receptor c-Kit has proven to play a role in normal female reproduction and fertility in mammals. Gene expression studies have revealed that biological activities of ligands and receptors of the KL/c-Kit system are important in controlling apoptosis and cellular proliferation in reproductive tissues. Collectively, these studies have provided a better understanding of ovarian physiology and female fertility through the establishment of the concept that the KL/c-Kit system regulates the viability of primordial germ cells and follicles, initiation of primordial follicle growth, and further oocyte and follicular development through different signaling proteins. The purpose of this article is to review the importance of the KL/c-Kit system in ovarian follicular development, especially in the preantral phase of folliculogenesis.(AU)
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Texto completo: 1 Base de dados: VETINDEX Idioma: En Revista: Anim. Reprod. / Anim. Reprod. (Online) Ano de publicação: 2009 Tipo de documento: Article
Texto completo: 1 Base de dados: VETINDEX Idioma: En Revista: Anim. Reprod. / Anim. Reprod. (Online) Ano de publicação: 2009 Tipo de documento: Article