Detalhe da pesquisa
1.
Mechanistic Basis for a Connection between the Catalytic Step and Slow Opening Dynamics of Adenylate Kinase.
J Chem Inf Model
; 63(5): 1556-1569, 2023 03 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36802243
2.
The bacterial curli system possesses a potent and selective inhibitor of amyloid formation.
Mol Cell
; 57(3): 445-55, 2015 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25620560
3.
Domain-specific insight into the recognition of BH3-death motifs by the pro-survival Bcl-2 protein.
Biophys J
; 121(23): 4517-4525, 2022 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36325615
4.
Dissociation between the critical role of ClpB of Francisella tularensis for the heat shock response and the DnaK interaction and its important role for efficient type VI secretion and bacterial virulence.
PLoS Pathog
; 16(4): e1008466, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32275693
5.
Tandem Ring Opening/Intramolecular [2 + 2] Cycloaddition Reaction for the Synthesis of Cyclobutane Fused Thiazolino-2-Pyridones.
J Org Chem
; 86(23): 16582-16592, 2021 12 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34767366
6.
K2S2O8-mediated coupling of 6-amino-7-aminomethyl-thiazolino-pyridones with aldehydes to construct amyloid affecting pyrimidine-fused thiazolino-2-pyridones.
Org Biomol Chem
; 19(44): 9758-9772, 2021 11 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34730163
7.
Synthetic NAC 71-82 Peptides Designed to Produce Fibrils with Different Protofilament Interface Contacts.
Int J Mol Sci
; 22(17)2021 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34502242
8.
Insight into Functional Membrane Proteins by Solution NMR: The Human Bcl-2 Protein-A Promising Cancer Drug Target.
Molecules
; 26(5)2021 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33800399
9.
A novel recombinant expression and purification approach for the full-length anti-apoptotic membrane protein Bcl-2.
Protein Expr Purif
; 172: 105628, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32209420
10.
Intramolecular Povarov Reactions for the Synthesis of Chromenopyridine Fused 2-Pyridone Polyheterocycles Binding to α-Synuclein and Amyloid-ß Fibrils.
J Org Chem
; 85(21): 14174-14189, 2020 11 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33099999
11.
Inhibition of curli assembly and Escherichia coli biofilm formation by the human systemic amyloid precursor transthyretin.
Proc Natl Acad Sci U S A
; 114(46): 12184-12189, 2017 11 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29087319
12.
A Capped Peptide of the Aggregation Prone NAC 71-82 Amino Acid Stretch of α-Synuclein Folds into Soluble ß-Sheet Oligomers at Low and Elevated Peptide Concentrations.
Int J Mol Sci
; 21(5)2020 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32120928
13.
Viral mimetic priming enhances α-synuclein-induced degeneration: Implications for Parkinson's disease.
Brain Behav Immun
; 80: 525-535, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31029796
14.
Bax to the future - A novel, high-yielding approach for purification and expression of full-length Bax protein for structural studies.
Protein Expr Purif
; 158: 20-26, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30738180
15.
Pyridine-Fused 2-Pyridones via Povarov and A3 Reactions: Rapid Generation of Highly Functionalized Tricyclic Heterocycles Capable of Amyloid Fibril Binding.
J Org Chem
; 84(7): 3887-3903, 2019 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30862161
16.
Copper binding triggers compaction in N-terminal tail of human copper pump ATP7B.
Biochem Biophys Res Commun
; 470(3): 663-669, 2016 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-26797276
17.
Correlated inter-domain motions in adenylate kinase.
PLoS Comput Biol
; 10(7): e1003721, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25078441
18.
Human cytoplasmic copper chaperones Atox1 and CCS exchange copper ions in vitro.
Biometals
; 28(3): 577-85, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25673218
19.
Macromolecular crowding effects on two homologs of ribosomal protein s16: protein-dependent structural changes and local interactions.
Biophys J
; 107(2): 401-410, 2014 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25028882
20.
Folding of an unfolded protein by macromolecular crowding in vitro.
Biochemistry
; 53(14): 2271-7, 2014 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24665900