Detalhe da pesquisa
1.
Bi-allelic JAM2 Variants Lead to Early-Onset Recessive Primary Familial Brain Calcification.
Am J Hum Genet
; 106(3): 412-421, 2020 03 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32142645
2.
The translocator protein (TSPO) is prodromal to mitophagy loss in neurotoxicity.
Mol Psychiatry
; 26(7): 2721-2739, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33664474
3.
Hsp90 Inhibition: A Promising Therapeutic Approach for ARSACS.
Int J Mol Sci
; 22(21)2021 Oct 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34769152
4.
A reduction in Drp1-mediated fission compromises mitochondrial health in autosomal recessive spastic ataxia of Charlevoix Saguenay.
Hum Mol Genet
; 25(15): 3232-3244, 2016 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27288452
5.
Mitochondrial Ca(2+) in neurodegenerative disorders.
Pharmacol Res
; 99: 377-81, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26013908
6.
Targeting lipid peroxidation and mitochondrial imbalance in Friedreich's ataxia.
Pharmacol Res
; 99: 344-50, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26141703
7.
Inhibition of LRRK2 kinase activity stimulates macroautophagy.
Biochim Biophys Acta
; 1833(12): 2900-2910, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23916833
8.
Activation of PARP by oxidative stress induced by ß-amyloid: implications for Alzheimer's disease.
Neurochem Res
; 37(11): 2589-96, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23076628
9.
Beta-amyloid activates PARP causing astrocytic metabolic failure and neuronal death.
Brain
; 134(Pt 6): 1658-72, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21616968
10.
A Drug Combination Rescues Frataxin-Dependent Neural and Cardiac Pathophysiology in FA Models.
Front Mol Biosci
; 9: 830650, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35664670
11.
NH-sulfoximine: A novel pharmacological inhibitor of the mitochondrial F1 Fo -ATPase, which suppresses viability of cancerous cells.
Br J Pharmacol
; 178(2): 298-311, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33037618
12.
IF1, the endogenous regulator of the F(1)F(o)-ATPsynthase, defines mitochondrial volume fraction in HeLa cells by regulating autophagy.
Biochim Biophys Acta
; 1787(5): 393-401, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19269273
13.
Mitochondria form contact sites with the nucleus to couple prosurvival retrograde response.
Sci Adv
; 6(51)2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33355129
14.
CLIC1 function is required for beta-amyloid-induced generation of reactive oxygen species by microglia.
J Neurosci
; 28(45): 11488-99, 2008 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-18987185
15.
Xeroderma pigmentosum: overview of pharmacology and novel therapeutic strategies for neurological symptoms.
Br J Pharmacol
; 176(22): 4293-4301, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30499105
16.
Blockade of chloride intracellular ion channel 1 stimulates Abeta phagocytosis.
J Neurosci Res
; 86(11): 2488-98, 2008 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18438938
17.
Novel Nrf2-Inducer Prevents Mitochondrial Defects and Oxidative Stress in Friedreich's Ataxia Models.
Front Cell Neurosci
; 12: 188, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30065630
18.
Calcium Deregulation: Novel Insights to Understand Friedreich's Ataxia Pathophysiology.
Front Cell Neurosci
; 12: 264, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30333728
19.
mTOR independent alteration in ULK1 Ser758 phosphorylation following chronic LRRK2 kinase inhibition.
Biosci Rep
; 38(2)2018 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29563162
20.
Complexity of the Genetics and Clinical Presentation of Spinocerebellar Ataxia 17.
Front Cell Neurosci
; 12: 429, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30532692