Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Integration of Single-Cell Genomics Datasets.

Adey, Andrew C.

Cell ; 177(7): 1677-1679, 2019 06 13.

Artigo em Inglês | MEDLINE | ID: mdl-31199914

2.

High-Throughput Single-Cell Sequencing with Linear Amplification.

Yin, Yi; Jiang, Yue; Lam, Kwan-Wood Gabriel; Berletch, Joel B; Disteche, Christine M; Noble, William S; Steemers, Frank J; Camerini-Otero, R Daniel; Adey, Andrew C; Shendure, Jay.

Mol Cell ; 76(4): 676-690.e10, 2019 11 21.

Artigo em Inglês | MEDLINE | ID: mdl-31495564

3.

Atlas-scale single-cell chromatin accessibility using nanowell-based combinatorial indexing.

O'Connell, Brendan L; Nichols, Ruth V; Pokholok, Dmitry; Thomas, Jerushah; Acharya, Sonia N; Nishida, Andrew; Thornton, Casey A; Co, Marissa; Fields, Andrew J; Steemers, Frank J; Adey, Andrew C.

Genome Res ; 33(2): 208-217, 2023 02.

Artigo em Inglês | MEDLINE | ID: mdl-36792372

4.

The TLK-ASF1 histone chaperone pathway plays a critical role in IL-1b-mediated AML progression.

Lin, Hsin-Yun; M Hosseini, Mona; McClatchy, John; Villamor-Payà, Marina; Jeng, Sophia; Bottomly, Daniel; Tsai, Chia-Feng; Posso, Camilo; Jacobson, Jeremy; Adey, Andrew C; Gosline, Sara J C; Liu, Tao; McWeeney, Shannon K; Stracker, Travis H; Agarwal, Anupriya.

Blood ; 2024 Mar 18.

Artigo em Inglês | MEDLINE | ID: mdl-38498025

5.

Cicero Predicts cis-Regulatory DNA Interactions from Single-Cell Chromatin Accessibility Data.

Pliner, Hannah A; Packer, Jonathan S; McFaline-Figueroa, José L; Cusanovich, Darren A; Daza, Riza M; Aghamirzaie, Delasa; Srivatsan, Sanjay; Qiu, Xiaojie; Jackson, Dana; Minkina, Anna; Adey, Andrew C; Steemers, Frank J; Shendure, Jay; Trapnell, Cole.

Mol Cell ; 71(5): 858-871.e8, 2018 09 06.

Artigo em Inglês | MEDLINE | ID: mdl-30078726

6.

Tagmentation-based single-cell genomics.

Adey, Andrew C.

Genome Res ; 31(10): 1693-1705, 2021 10.

Artigo em Inglês | MEDLINE | ID: mdl-34599003

7.

Shared and Distinct Functional Effects of Patient-Specific Tbr1 Mutations on Cortical Development.

Co, Marissa; Barnard, Rebecca A; Jahncke, Jennifer N; Grindstaff, Sally; Fedorov, Lev M; Adey, Andrew C; Wright, Kevin M; O'Roak, Brian J.

J Neurosci ; 42(37): 7166-7181, 2022 09 14.

Artigo em Inglês | MEDLINE | ID: mdl-35944998

8.

The accessible chromatin landscape of the murine hippocampus at single-cell resolution.

Sinnamon, John R; Torkenczy, Kristof A; Linhoff, Michael W; Vitak, Sarah A; Mulqueen, Ryan M; Pliner, Hannah A; Trapnell, Cole; Steemers, Frank J; Mandel, Gail; Adey, Andrew C.

Genome Res ; 29(5): 857-869, 2019 05.

Artigo em Inglês | MEDLINE | ID: mdl-30936163

9.

Age-dependent transcriptional alterations in cardiac endothelial cells.

Emechebe, Uchenna; Nelson, Jonathan W; Alkayed, Nabil J; Kaul, Sanjiv; Adey, Andrew C; Barnes, Anthony P.

Physiol Genomics ; 53(7): 295-308, 2021 07 01.

Artigo em Inglês | MEDLINE | ID: mdl-34097533

10.

Single-cell multiomics to probe relationships between histone modifications and transcription.

Adey, Andrew C.

Nat Methods ; 18(6): 602-603, 2021 06.

Artigo em Inglês | MEDLINE | ID: mdl-33958789

11.

Haplotype resolution at the single-cell level.

Adey, Andrew C.

Proc Natl Acad Sci U S A ; 114(47): 12362-12364, 2017 11 21.

Artigo em Inglês | MEDLINE | ID: mdl-29114045

12.

txci-ATAC-seq: a massive-scale single-cell technique to profile chromatin accessibility.

Zhang, Hao; Mulqueen, Ryan M; Iannuzo, Natalie; Farrera, Dominique O; Polverino, Francesca; Galligan, James J; Ledford, Julie G; Adey, Andrew C; Cusanovich, Darren A.

Genome Biol ; 25(1): 78, 2024 Mar 22.

Artigo em Inglês | MEDLINE | ID: mdl-38519979

13.

Meet the author: Andrew Adey.

Adey, Andrew C.

Cell Rep Methods ; 3(11): 100648, 2023 Nov 20.

Artigo em Inglês | MEDLINE | ID: mdl-37989084

14.

sciMET-cap: High-throughput single-cell methylation analysis with a reduced sequencing burden.

Acharya, Sonia N; Nichols, Ruth V; Rylaarsdam, Lauren E; O'Connell, Brendan L; Braun, Theodore P; Adey, Andrew C.

bioRxiv ; 2023 Jul 14.

Artigo em Inglês | MEDLINE | ID: mdl-37502923

15.

BET inhibitors rescue anti-PD1 resistance by enhancing TCF7 accessibility in leukemia-derived terminally exhausted CD8⁺ T cells.

Romine, Kyle A; MacPherson, Kevin; Cho, Hyun-Jun; Kosaka, Yoko; Flynn, Patrick A; Byrd, Kaelan H; Coy, Jesse L; Newman, Matthew T; Pandita, Ravina; Loo, Christopher P; Scott, Jaime; Adey, Andrew C; Lind, Evan F.

Leukemia ; 37(3): 580-592, 2023 03.

Artigo em Inglês | MEDLINE | ID: mdl-36681742

16.

Supervised learning of high-confidence phenotypic subpopulations from single-cell data.

Ren, Tao; Chen, Canping; Danilov, Alexey V; Liu, Susan; Guan, Xiangnan; Du, Shunyi; Wu, Xiwei; Sherman, Mara H; Spellman, Paul T; Coussens, Lisa M; Adey, Andrew C; Mills, Gordon B; Wu, Ling-Yun; Xia, Zheng.

bioRxiv ; 2023 Mar 25.

Artigo em Inglês | MEDLINE | ID: mdl-36993424

17.

Accessible high-throughput single-cell whole-genome sequencing with paired chromatin accessibility.

Queitsch, Konstantin; Moore, Travis W; O'Connell, Brendan L; Nichols, Ruth V; Muschler, John L; Keith, Dove; Lopez, Charles; Sears, Rosalie C; Mills, Gordon B; Yardimci, Galip Gürkan; Adey, Andrew C.

Cell Rep Methods ; 3(11): 100625, 2023 Nov 20.

Artigo em Inglês | MEDLINE | ID: mdl-37918402

18.

Systematic benchmarking of single-cell ATAC-sequencing protocols.

De Rop, Florian V; Hulselmans, Gert; Flerin, Chris; Soler-Vila, Paula; Rafels, Albert; Christiaens, Valerie; González-Blas, Carmen Bravo; Marchese, Domenica; Caratù, Ginevra; Poovathingal, Suresh; Rozenblatt-Rosen, Orit; Slyper, Michael; Luo, Wendy; Muus, Christoph; Duarte, Fabiana; Shrestha, Rojesh; Bagdatli, S Tansu; Corces, M Ryan; Mamanova, Lira; Knights, Andrew; Meyer, Kerstin B; Mulqueen, Ryan; Taherinasab, Akram; Maschmeyer, Patrick; Pezoldt, Jörn; Lambert, Camille Lucie Germaine; Iglesias, Marta; Najle, Sebastián R; Dossani, Zain Y; Martelotto, Luciano G; Burkett, Zach; Lebofsky, Ronald; Martin-Subero, José Ignacio; Pillai, Satish; Sebé-Pedrós, Arnau; Deplancke, Bart; Teichmann, Sarah A; Ludwig, Leif S; Braun, Theodore P; Adey, Andrew C; Greenleaf, William J; Buenrostro, Jason D; Regev, Aviv; Aerts, Stein; Heyn, Holger.

Nat Biotechnol ; 2023 Aug 03.

Artigo em Inglês | MEDLINE | ID: mdl-37537502

19.

High-throughput robust single-cell DNA methylation profiling with sciMETv2.

Nichols, Ruth V; O'Connell, Brendan L; Mulqueen, Ryan M; Thomas, Jerushah; Woodfin, Ashley R; Acharya, Sonia; Mandel, Gail; Pokholok, Dmitry; Steemers, Frank J; Adey, Andrew C.

Nat Commun ; 13(1): 7627, 2022 Dec 09.

Artigo em Inglês | MEDLINE | ID: mdl-36494343

20.

Identifying phenotype-associated subpopulations by integrating bulk and single-cell sequencing data.

Sun, Duanchen; Guan, Xiangnan; Moran, Amy E; Wu, Ling-Yun; Qian, David Z; Schedin, Pepper; Dai, Mu-Shui; Danilov, Alexey V; Alumkal, Joshi J; Adey, Andrew C; Spellman, Paul T; Xia, Zheng.

Nat Biotechnol ; 40(4): 527-538, 2022 04.

Artigo em Inglês | MEDLINE | ID: mdl-34764492

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Integration of Single-Cell Genomics Datasets.

High-Throughput Single-Cell Sequencing with Linear Amplification.

Atlas-scale single-cell chromatin accessibility using nanowell-based combinatorial indexing.

The TLK-ASF1 histone chaperone pathway plays a critical role in IL-1b-mediated AML progression.

Cicero Predicts cis-Regulatory DNA Interactions from Single-Cell Chromatin Accessibility Data.

Tagmentation-based single-cell genomics.

Shared and Distinct Functional Effects of Patient-Specific Tbr1 Mutations on Cortical Development.

The accessible chromatin landscape of the murine hippocampus at single-cell resolution.

Age-dependent transcriptional alterations in cardiac endothelial cells.

Single-cell multiomics to probe relationships between histone modifications and transcription.

Haplotype resolution at the single-cell level.

txci-ATAC-seq: a massive-scale single-cell technique to profile chromatin accessibility.

Meet the author: Andrew Adey.

sciMET-cap: High-throughput single-cell methylation analysis with a reduced sequencing burden.

BET inhibitors rescue anti-PD1 resistance by enhancing TCF7 accessibility in leukemia-derived terminally exhausted CD8⁺ T cells.

Supervised learning of high-confidence phenotypic subpopulations from single-cell data.

Accessible high-throughput single-cell whole-genome sequencing with paired chromatin accessibility.

Systematic benchmarking of single-cell ATAC-sequencing protocols.

High-throughput robust single-cell DNA methylation profiling with sciMETv2.

Identifying phenotype-associated subpopulations by integrating bulk and single-cell sequencing data.