Detalhe da pesquisa
1.
Lactate induces metabolic and epigenetic reprogramming of pro-inflammatory Th17 cells.
EMBO Rep
; 23(12): e54685, 2022 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36215678
2.
KLF4-mediated upregulation of the NKG2D ligand MICA in acute myeloid leukemia: a novel therapeutic target identified by enChIP.
Cell Commun Signal
; 21(1): 94, 2023 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37143070
3.
The mammalian Hedgehog pathway is modulated by ANP32 proteins.
Biochem Biophys Res Commun
; 553: 78-84, 2021 05 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33761414
4.
PPARß/δ recruits NCOR and regulates transcription reinitiation of ANGPTL4.
Nucleic Acids Res
; 47(18): 9573-9591, 2019 10 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31428774
5.
Proteotranscriptomics Reveal Signaling Networks in the Ovarian Cancer Microenvironment.
Mol Cell Proteomics
; 17(2): 270-289, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29141914
6.
Lysophosphatidylcholines activate PPARδ and protect human skeletal muscle cells from lipotoxicity.
Biochim Biophys Acta
; 1861(12 Pt A): 1980-1992, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27697477
7.
Interferon signaling in ascites-associated macrophages is linked to a favorable clinical outcome in a subgroup of ovarian carcinoma patients.
BMC Genomics
; 18(1): 243, 2017 03 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28327095
8.
The transcriptional PPARß/δ network in human macrophages defines a unique agonist-induced activation state.
Nucleic Acids Res
; 43(10): 5033-51, 2015 May 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25934804
9.
Reverse crosstalk of TGFß and PPARß/δ signaling identified by transcriptional profiling.
Nucleic Acids Res
; 39(1): 119-31, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20846954
10.
Tumor-suppressive disruption of cancer subtype-associated super enhancer circuits by small molecule treatment.
NAR Cancer
; 5(1): zcad007, 2023 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-36755960
11.
High-affinity peroxisome proliferator-activated receptor ß/δ-specific ligands with pure antagonistic or inverse agonistic properties.
Mol Pharmacol
; 80(5): 828-38, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21862691
12.
Transcriptional profiling identifies functional interactions of TGF ß and PPAR ß/δ signaling: synergistic induction of ANGPTL4 transcription.
J Biol Chem
; 285(38): 29469-79, 2010 Sep 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-20595396
13.
Activation of Cilia-Independent Hedgehog/GLI1 Signaling as a Novel Concept for Neuroblastoma Therapy.
Cancers (Basel)
; 13(8)2021 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33921042
14.
15-hydroxyeicosatetraenoic acid is a preferential peroxisome proliferator-activated receptor beta/delta agonist.
Mol Pharmacol
; 77(2): 171-84, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19903832
15.
The short-chain fatty acid pentanoate suppresses autoimmunity by modulating the metabolic-epigenetic crosstalk in lymphocytes.
Nat Commun
; 10(1): 760, 2019 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30770822
16.
Regulation of the effector function of CD8+ T cells by gut microbiota-derived metabolite butyrate.
Sci Rep
; 8(1): 14430, 2018 09 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30258117
17.
Chromatin Binding of c-REL and p65 Is Not Limiting for Macrophage IL12B Transcription During Immediate Suppression by Ovarian Carcinoma Ascites.
Front Immunol
; 9: 1425, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29997615
18.
Epigenome-wide DNA methylation profiling in Progressive Supranuclear Palsy reveals major changes at DLX1.
Nat Commun
; 9(1): 2929, 2018 07 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30050033
19.
The Unique Molecular and Cellular Microenvironment of Ovarian Cancer.
Front Oncol
; 7: 24, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28275576
20.
Design and Synthesis of Highly Active Peroxisome Proliferator-Activated Receptor (PPAR) ß/δ Inverse Agonists with Prolonged Cellular Activity.
ChemMedChem
; 11(5): 488-96, 2016 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26864558