Detalhe da pesquisa
1.
Development of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13.
Cell
; 170(2): 249-259.e25, 2017 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-28669536
2.
An Antibacterial ß-Lactone Kills Mycobacterium tuberculosis by Disrupting Mycolic Acid Biosynthesis.
Angew Chem Int Ed Engl
; 57(1): 348-353, 2018 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29067779
3.
Selective CK1α degraders exert antiproliferative activity against a broad range of human cancer cell lines.
Nat Commun
; 15(1): 482, 2024 Jan 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38228616
4.
Phenyl Dihydrouracil: An Alternative Cereblon Binder for PROTAC Design.
ACS Med Chem Lett
; 14(2): 141-145, 2023 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36793425
5.
Structural basis of BAK activation in mitochondrial apoptosis initiation.
Nat Commun
; 13(1): 250, 2022 01 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35017502
6.
Optimization of TAM16, a Benzofuran That Inhibits the Thioesterase Activity of Pks13; Evaluation toward a Preclinical Candidate for a Novel Antituberculosis Clinical Target.
J Med Chem
; 65(1): 409-423, 2022 01 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34910486
7.
Mycobacterium tuberculosis acyl carrier protein synthase adopts two different pH-dependent structural conformations.
Acta Crystallogr D Biol Crystallogr
; 67(Pt 7): 657-69, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21697604
8.
A Sec14-like phosphatidylinositol transfer protein paralog defines a novel class of heme-binding proteins.
Elife
; 92020 08 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32780017
9.
Crystal structure of calcium dodecin (Rv0379), from Mycobacterium tuberculosis with a unique calcium-binding site.
Protein Sci
; 20(5): 827-33, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21370306