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Andrologia ; 51(10): e13403, 2019 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-31434165

RESUMO

The most recent technologies for sperm sorting involve microfluidics. However, the most important question whether their use is of any advantage in terms of laboratory and clinical IVF/ICSI outcomes still remains controversy. In this study, we aimed to investigate whether a microfluidic sperm sorting device (Fertile Plus® ) has a positive add-on effect on laboratory and clinical outcomes. Sibling oocytes of 81 patients were assigned to two sperm sorting groups including swim up and Fertile Plus® . All embryos were cultured until day 5/6. Fertilisation, embryo quality and blastocyst development were assessed as primary outcomes among 81 patients; clinical pregnancy, implantation and live birth rates were analysed as secondary outcomes as a subgroup analysis due to transfer cancellations. No statistically significant differences were found between groups in terms of all outcomes analysed in laboratory and clinical terms (p > .05 for all). The results of this study suggest that sorting spermatozoa through Fertile chip does not improve laboratory outcomes significantly and does not seem to have a positive contribution to clinical outcomes.


Assuntos
Separação Celular/instrumentação , Infertilidade Masculina/terapia , Dispositivos Lab-On-A-Chip , Injeções de Esperma Intracitoplásmicas/métodos , Espermatozoides , Adulto , Coeficiente de Natalidade , Separação Celular/métodos , Feminino , Humanos , Masculino , Oócitos , Gravidez , Taxa de Gravidez , Irmãos , Resultado do Tratamento , Adulto Jovem
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