Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Mechanisms of microtubule organization in differentiated animal cells.

Akhmanova, Anna; Kapitein, Lukas C.

Nat Rev Mol Cell Biol ; 23(8): 541-558, 2022 08.

Artigo em Inglês | MEDLINE | ID: mdl-35383336

2.

Microtubule-Organizing Centers.

Wu, Jingchao; Akhmanova, Anna.

Annu Rev Cell Dev Biol ; 33: 51-75, 2017 10 06.

Artigo em Inglês | MEDLINE | ID: mdl-28645217

3.

Dynein recruitment to nuclear pores activates apical nuclear migration and mitotic entry in brain progenitor cells.

Hu, Daniel Jun-Kit; Baffet, Alexandre Dominique; Nayak, Tania; Akhmanova, Anna; Doye, Valérie; Vallee, Richard Bert.

Cell ; 154(6): 1300-13, 2013 Sep 12.

Artigo em Inglês | MEDLINE | ID: mdl-24034252

4.

Pharmaceutical-Grade Rigosertib Is a Microtubule-Destabilizing Agent.

Jost, Marco; Chen, Yuwen; Gilbert, Luke A; Horlbeck, Max A; Krenning, Lenno; Menchon, Grégory; Rai, Ankit; Cho, Min Y; Stern, Jacob J; Prota, Andrea E; Kampmann, Martin; Akhmanova, Anna; Steinmetz, Michel O; Tanenbaum, Marvin E; Weissman, Jonathan S.

Mol Cell ; 79(1): 191-198.e3, 2020 07 02.

Artigo em Inglês | MEDLINE | ID: mdl-32619469

5.

Control of microtubule organization and dynamics: two ends in the limelight.

Akhmanova, Anna; Steinmetz, Michel O.

Nat Rev Mol Cell Biol ; 16(12): 711-26, 2015 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-26562752

6.

GelMap: intrinsic calibration and deformation mapping for expansion microscopy.

Damstra, Hugo G J; Passmore, Josiah B; Serweta, Albert K; Koutlas, Ioannis; Burute, Mithila; Meye, Frank J; Akhmanova, Anna; Kapitein, Lukas C.

Nat Methods ; 20(10): 1573-1580, 2023 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-37723243

7.

The Role of MAPRE2 and Microtubules in Maintaining Normal Ventricular Conduction.

Chiang, David Y; Verkerk, Arie O; Victorio, Rachelle; Shneyer, Boris I; van der Vaart, Babet; Jouni, Mariam; Narendran, Nakul; Kc, Ashmita; Sampognaro, James R; Vetrano-Olsen, Franki; Oh, John S; Buys, Eva; de Jonge, Berend; Shah, Disheet A; Kiviniemi, Tuomas; Burridge, Paul W; Bezzina, Connie R; Akhmanova, Anna; MacRae, Calum A.

Circ Res ; 134(1): 46-59, 2024 01 05.

Artigo em Inglês | MEDLINE | ID: mdl-38095085

8.

Kinesins lead aging microtubules to catastrophe.

Akhmanova, Anna; Dogterom, Marileen.

Cell ; 147(5): 966-8, 2011 Nov 23.

Artigo em Inglês | MEDLINE | ID: mdl-22118452

9.

Estimation of microtubule-generated forces using a DNA origami nanospring.

Nick Maleki, Ali; Huis In 't Veld, Pim J; Akhmanova, Anna; Dogterom, Marileen; Volkov, Vladimir A.

J Cell Sci ; 136(5)2023 03 01.

Artigo em Inglês | MEDLINE | ID: mdl-36074043

10.

The centriolar satellite protein Cfap53 facilitates formation of the zygotic microtubule organizing center in the zebrafish embryo.

Willekers, Sven; Tessadori, Federico; van der Vaart, Babet; Henning, Heiko H; Stucchi, Riccardo; Altelaar, Maarten; Roelen, Bernard A J; Akhmanova, Anna; Bakkers, Jeroen.

Development ; 149(16)2022 08 15.

Artigo em Inglês | MEDLINE | ID: mdl-35980365

11.

Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent.

Jost, Marco; Chen, Yuwen; Gilbert, Luke A; Horlbeck, Max A; Krenning, Lenno; Menchon, Grégory; Rai, Ankit; Cho, Min Y; Stern, Jacob J; Prota, Andrea E; Kampmann, Martin; Akhmanova, Anna; Steinmetz, Michel O; Tanenbaum, Marvin E; Weissman, Jonathan S.

Mol Cell ; 68(1): 210-223.e6, 2017 Oct 05.

Artigo em Inglês | MEDLINE | ID: mdl-28985505

12.

Cross-linkers at growing microtubule ends generate forces that drive actin transport.

Alkemade, Celine; Wierenga, Harmen; Volkov, Vladimir A; Preciado López, Magdalena; Akhmanova, Anna; Ten Wolde, Pieter Rein; Dogterom, Marileen; Koenderink, Gijsje H.

Proc Natl Acad Sci U S A ; 119(11): e2112799119, 2022 03 15.

Artigo em Inglês | MEDLINE | ID: mdl-35271394

13.

Angiomotin isoform 2 promotes binding of PALS1 to KIF13B at primary cilia and regulates ciliary length and signaling.

Morthorst, Stine Kjær; Nielsen, Camilla; Farinelli, Pietro; Anvarian, Zeinab; Rasmussen, Christina Birgitte R; Serra-Marques, Andrea; Grigoriev, Ilya; Altelaar, Maarten; Fürstenberg, Nicoline; Ludwig, Alexander; Akhmanova, Anna; Christensen, Søren Tvorup; Pedersen, Lotte Bang.

J Cell Sci ; 135(12)2022 06 15.

Artigo em Inglês | MEDLINE | ID: mdl-35673984

14.

Organization and dynamics of the cortical complexes controlling insulin secretion in ß-cells.

Noordstra, Ivar; van den Berg, Cyntha M; Boot, Fransje W J; Katrukha, Eugene A; Yu, Ka Lou; Tas, Roderick P; Portegies, Sybren; Viergever, Bastiaan J; de Graaff, Esther; Hoogenraad, Casper C; de Koning, Eelco J P; Carlotti, Françoise; Kapitein, Lukas C; Akhmanova, Anna.

J Cell Sci ; 135(3)2022 02 01.

Artigo em Inglês | MEDLINE | ID: mdl-35006275

15.

Compressive forces stabilize microtubules in living cells.

Li, Yuhui; Kucera, Ondrej; Cuvelier, Damien; Rutkowski, David M; Deygas, Mathieu; Rai, Dipti; Pavlovic, Tonja; Vicente, Filipe Nunes; Piel, Matthieu; Giannone, Grégory; Vavylonis, Dimitrios; Akhmanova, Anna; Blanchoin, Laurent; Théry, Manuel.

Nat Mater ; 22(7): 913-924, 2023 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-37386067

16.

An EB1-binding motif acts as a microtubule tip localization signal.

Honnappa, Srinivas; Gouveia, Susana Montenegro; Weisbrich, Anke; Damberger, Fred F; Bhavesh, Neel S; Jawhari, Hatim; Grigoriev, Ilya; van Rijssel, Frederik J A; Buey, Ruben M; Lawera, Aleksandra; Jelesarov, Ilian; Winkler, Fritz K; Wüthrich, Kurt; Akhmanova, Anna; Steinmetz, Michel O.

Cell ; 138(2): 366-76, 2009 Jul 23.

Artigo em Inglês | MEDLINE | ID: mdl-19632184

17.

Lattice defects induced by microtubule-stabilizing agents exert a long-range effect on microtubule growth by promoting catastrophes.

Rai, Ankit; Liu, Tianyang; Katrukha, Eugene A; Estévez-Gallego, Juan; Manka, Szymon W; Paterson, Ian; Díaz, J Fernando; Kapitein, Lukas C; Moores, Carolyn A; Akhmanova, Anna.

Proc Natl Acad Sci U S A ; 118(51)2021 12 21.

Artigo em Inglês | MEDLINE | ID: mdl-34916292

18.

Organizing junctions at the cell-cell interface.

Akhmanova, Anna; Yap, Alpha S.

Cell ; 135(5): 791-3, 2008 Nov 28.

Artigo em Inglês | MEDLINE | ID: mdl-19041742

19.

In Vivo Photocontrol of Microtubule Dynamics and Integrity, Migration and Mitosis, by the Potent GFP-Imaging-Compatible Photoswitchable Reagents SBTubA4P and SBTub2M.

Gao, Li; Meiring, Joyce C M; Varady, Adam; Ruider, Iris E; Heise, Constanze; Wranik, Maximilian; Velasco, Cecilia D; Taylor, Jennifer A; Terni, Beatrice; Weinert, Tobias; Standfuss, Jörg; Cabernard, Clemens C; Llobet, Artur; Steinmetz, Michel O; Bausch, Andreas R; Distel, Martin; Thorn-Seshold, Julia; Akhmanova, Anna; Thorn-Seshold, Oliver.

J Am Chem Soc ; 144(12): 5614-5628, 2022 03 30.

Artigo em Inglês | MEDLINE | ID: mdl-35290733

20.

A drug discovery platform to identify compounds that inhibit EGFR triple mutants.

Saraon, Punit; Snider, Jamie; Kalaidzidis, Yannis; Wybenga-Groot, Leanne E; Weiss, Konstantin; Rai, Ankit; Radulovich, Nikolina; Drecun, Luka; Vuckovic, Nika; Vucetic, Adriana; Wong, Victoria; Thériault, Brigitte; Pham, Nhu-An; Park, Jin H; Datti, Alessandro; Wang, Jenny; Pathmanathan, Shivanthy; Aboualizadeh, Farzaneh; Lyakisheva, Anna; Yao, Zhong; Wang, Yuhui; Joseph, Babu; Aman, Ahmed; Moran, Michael F; Prakesch, Michael; Poda, Gennady; Marcellus, Richard; Uehling, David; Samarzija, Miroslav; Jakopovic, Marko; Tsao, Ming-Sound; Shepherd, Frances A; Sacher, Adrian; Leighl, Natasha; Akhmanova, Anna; Al-Awar, Rima; Zerial, Marino; Stagljar, Igor.

Nat Chem Biol ; 16(5): 577-586, 2020 05.

Artigo em Inglês | MEDLINE | ID: mdl-32094923

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