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1.
Saudi Med J ; 39(8): 787-791, 2018 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-30106416

RESUMO

OBJECTIVES: To determine the outcomes  of endoscopic dilatation of esophageal strictures in children. METHODS: Children younger than 18 years of age diagnosed with esophageal strictures over a period of 7 years (June 2010 to June 2017) were reviewed and analyzed retrospectively. The study took place at King Khalid University Hospital, Riyadh, Saudi Arabia. The patients' clinical characteristics, endoscopic findings, and details of the strictures, treatment, and outcomes were documented. RESULTS: Forty-three children with esophageal strictures were identified (median age, 8.1 years; range, 2-17 years; 23 [53.5%] boys). The median age at presentation was 2 years (range, 1-16 years), and the median follow-up period was 3 years (range, one month-17 years). Tracheoesophageal fistula (n=14, 32.6%), gastroesophageal reflux disease (n=10, 23.3%) and eosinophilic esophagitis (n=8, 18.6%) were the leading causes of esophageal strictures. Forty-three patients underwent 180 dilatation sessions; the median number of dilatation sessions per patient was 3 (range, 1-48), and the median interval between sessions was 8 weeks (range, 1-24 weeks). Among 180 dilatation sessions, 3 events (1.7%) of esophageal perforation were observed. The outcomes varied depending on the primary cause of the stricture; complete response was achieved the best in eosinophilic esophagitis-related strictures (87.5%), followed by anastomotic strictures post tracheoesophageal fistula repair (71.4%) and gastroesophageal reflux disease-related strictures (70%). CONCLUSION: Endoscopic dilatation is a safe and effective intervention in the management of esophageal strictures in children, with minimal complications when conducted by experts.


Assuntos
Dilatação/métodos , Estenose Esofágica/terapia , Esofagoscopia/métodos , Adolescente , Criança , Pré-Escolar , Dilatação/efeitos adversos , Esofagoscopia/efeitos adversos , Feminino , Humanos , Masculino , Estudos Retrospectivos , Resultado do Tratamento
3.
Saudi Med J ; 34(10): 1068-72, 2013 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-24145943

RESUMO

Basidiobolomycosis is a rare fungal infection caused by basidiobolus ranarum. The vast majority of gastrointestinal basidiobolomycosis cases were reported from tropical and subtropical regions. We report a Saudi pediatric patient with ileal basidiobolomycosis and initial clinical presentation mimicking acute appendicitis before being misdiagnosed as Crohn's disease. Our case is the first to report effective treatment of pediatric gastrointestinal basidiobolomycosis using voriconazole mono-therapy. In addition, we present extensive review of pediatric gastrointestinal basidiobolomycosis in medical literature.


Assuntos
Antifúngicos/uso terapêutico , Doença de Crohn/diagnóstico , Pirimidinas/uso terapêutico , Triazóis/uso terapêutico , Zigomicose/diagnóstico , Pré-Escolar , Doença de Crohn/tratamento farmacológico , Doença de Crohn/fisiopatologia , Diagnóstico Diferencial , Humanos , Masculino , Voriconazol , Zigomicose/tratamento farmacológico , Zigomicose/fisiopatologia
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